Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6RVQ
DownloadVisualize
BU of 6rvq by Molmil
SaFtsz-GDP-EthGLy
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Cell division protein FtsZ, ...
Authors:Fernandez-Tornero, C, Andreu, J.M.
Deposit date:2019-05-31
Release date:2020-02-19
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.136 Å)
Cite:Nucleotide-induced folding of cell division protein FtsZ from Staphylococcus aureus.
Febs J., 287, 2020
6RVP
DownloadVisualize
BU of 6rvp by Molmil
SaFtsz-GDP-MetPyr
Descriptor: 1-methylpyrrolidin-2-one, CALCIUM ION, Cell division protein FtsZ, ...
Authors:Fernandez-Tornero, C, Andreu, J.M.
Deposit date:2019-05-31
Release date:2020-02-19
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Nucleotide-induced folding of cell division protein FtsZ from Staphylococcus aureus.
Febs J., 287, 2020
6RVN
DownloadVisualize
BU of 6rvn by Molmil
aFtsz-GDP-Wat
Descriptor: CALCIUM ION, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE
Authors:Fernandez-Tornero, C, Andreu, J.M.
Deposit date:2019-05-31
Release date:2020-02-19
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.242 Å)
Cite:Nucleotide-induced folding of cell division protein FtsZ from Staphylococcus aureus.
Febs J., 287, 2020
5XDT
DownloadVisualize
BU of 5xdt by Molmil
Staphylococcus aureus FtsZ 12-316 complexed with TXA707
Descriptor: 1-methylpyrrolidin-2-one, 2,6-bis(fluoranyl)-3-[[6-(trifluoromethyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]methoxy]benzamide, CALCIUM ION, ...
Authors:Fujita, J, Maeda, Y, Mizohata, E, Inoue, T, Kaul, M, Parhi, A.K, LaVoie, E.J, Pilch, D.S, Matsumura, H.
Deposit date:2017-03-30
Release date:2017-08-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural Flexibility of an Inhibitor Overcomes Drug Resistance Mutations in Staphylococcus aureus FtsZ
ACS Chem. Biol., 12, 2017
8HTB
DownloadVisualize
BU of 8htb by Molmil
Staphylococcus aureus FtsZ 12-316 complexed with TXH9179
Descriptor: 3-[(6-ethynyl-[1,3]thiazolo[5,4-b]pyridin-2-yl)methoxy]-2,6-bis(fluoranyl)benzamide, CALCIUM ION, Cell division protein FtsZ, ...
Authors:Bryan, E, Ferrer-Gonzalez, E, Sagong, H.Y, Fujita, J, Mark, L, Kaul, M, LaVoie, E.J, Matsumura, H, Pilch, D.S.
Deposit date:2022-12-21
Release date:2023-09-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural and Antibacterial Characterization of a New Benzamide FtsZ Inhibitor with Superior Bactericidal Activity and In Vivo Efficacy Against Multidrug-Resistant Staphylococcus aureus.
Acs Chem.Biol., 18, 2023
6UMK
DownloadVisualize
BU of 6umk by Molmil
Structure of E. coli FtsZ(L178E)-GDP complex
Descriptor: Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE
Authors:Schumacher, M.A.
Deposit date:2019-10-09
Release date:2020-02-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:High-resolution crystal structures of Escherichia coli FtsZ bound to GDP and GTP.
Acta Crystallogr.,Sect.F, 76, 2020
6KVP
DownloadVisualize
BU of 6kvp by Molmil
S. aureus FtsZ in complex with 3-(1-(5-bromo-4-(4-(trifluoromethyl)phenyl)oxazol-2-yl)ethoxy)-2,6-difluorobenzamide (compound 2)
Descriptor: 3-[(1R)-1-[5-bromanyl-4-[4-(trifluoromethyl)phenyl]-1,3-oxazol-2-yl]ethoxy]-2,6-bis(fluoranyl)benzamide, CALCIUM ION, Cell division protein FtsZ, ...
Authors:Ferrer-Gonzalez, E, Fujita, J, Yoshizawa, T, Nelson, J.M, Pilch, A.J, Hillman, E, Ozawa, M, Kuroda, N, Parhi, A.K, LaVoie, E.J, Matsumura, H, Pilch, D.S.
Deposit date:2019-09-05
Release date:2020-01-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure-Guided Design of a Fluorescent Probe for the Visualization of FtsZ in Clinically Important Gram-Positive and Gram-Negative Bacterial Pathogens.
Sci Rep, 9, 2019
6UNX
DownloadVisualize
BU of 6unx by Molmil
Structure of E. coli FtsZ(L178E)-GTP complex
Descriptor: Cell division protein FtsZ, GUANOSINE-5'-TRIPHOSPHATE
Authors:Schumacher, M.A.
Deposit date:2019-10-13
Release date:2020-02-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:High-resolution crystal structures of Escherichia coli FtsZ bound to GDP and GTP.
Acta Crystallogr.,Sect.F, 76, 2020
2R75
DownloadVisualize
BU of 2r75 by Molmil
Aquifex aeolicus FtsZ with 8-morpholino-GTP
Descriptor: 8-morpholin-4-ylguanosine 5'-(tetrahydrogen triphosphate), Cell division protein ftsZ, MAGNESIUM ION
Authors:Lappchen, T, Pinas, V.A, Hartog, A.F, Koomen, G.J, Schaffner-Barbero, C, Andreu, J.M, Trambaiolo, D, Lowe, J, Juhem, A, Popov, A.V, den Blaauwen, T.
Deposit date:2007-09-07
Release date:2008-07-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.402 Å)
Cite:Probing FtsZ and tubulin with C8-substituted GTP analogs reveals differences in their nucleotide binding sites
Chem.Biol., 15, 2008
4M8I
DownloadVisualize
BU of 4m8i by Molmil
1.43 Angstrom resolution crystal structure of cell division protein FtsZ (ftsZ) from Staphylococcus epidermidis RP62A in complex with GDP
Descriptor: Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, SULFATE ION
Authors:Halavaty, A.S, Minasov, G, Winsor, J, Dubrovska, I, Filippova, E.V, Olsen, D.B, Therien, A, Shuvalova, L, Young, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-08-13
Release date:2013-09-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:1.43 Angstrom resolution crystal structure of cell division protein FtsZ (ftsZ) from Staphylococcus epidermidis RP62A in complex with GDP
To be Published
7OHH
DownloadVisualize
BU of 7ohh by Molmil
SaFtsZ complexed with GDP and BeF3-
Descriptor: BERYLLIUM TRIFLUORIDE ION, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2021-05-11
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
7OMQ
DownloadVisualize
BU of 7omq by Molmil
SaFtsZ complexed with GDPPCP and Mn2+
Descriptor: 1,2-ETHANEDIOL, Cell division protein FtsZ, MANGANESE (II) ION, ...
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2021-05-24
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
5MN4
DownloadVisualize
BU of 5mn4 by Molmil
S. aureus FtsZ 12-316 F138A GDP Open form (1FOf)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE
Authors:Wagstaff, J.M, Tsim, M, Kureisaite-Ciziene, D, Lowe, J.
Deposit date:2016-12-12
Release date:2016-12-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A Polymerization-Associated Structural Switch in FtsZ That Enables Treadmilling of Model Filaments.
MBio, 8, 2017
7OMP
DownloadVisualize
BU of 7omp by Molmil
SaFtsZ complexed with GDPPCP and Mg2+
Descriptor: 1,2-ETHANEDIOL, Cell division protein FtsZ, MAGNESIUM ION, ...
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2021-05-24
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
6S8K
DownloadVisualize
BU of 6s8k by Molmil
Structure, Thermodynamics, and Kinetics of Plinabulin Binding to two Tubulin Isotypes
Descriptor: (3Z,6Z)-3-benzylidene-6-[(5-tert-butyl-1H-imidazol-4-yl)methylidene]piperazine-2,5-dione, Designed ankyrin repeat protein (DARPIN) D1, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Sharma, A, Olieric, N, Steinmetz, M.
Deposit date:2019-07-10
Release date:2019-11-27
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Structure, Thermodynamics, and Kinetics of Plinabulin Binding to Two Tubulin Isotypes
Chem, 5, 2019
6YD5
DownloadVisualize
BU of 6yd5 by Molmil
SaFtsZ-UCM151 (comp. 18)
Descriptor: 1,2-ETHANEDIOL, 1-methylpyrrolidin-2-one, 3-[(3-chlorophenyl)methoxy]-2,6-bis(fluoranyl)benzamide, ...
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2020-03-20
Release date:2021-07-28
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery.
J.Med.Chem., 64, 2021
7OMJ
DownloadVisualize
BU of 7omj by Molmil
SaFtsZ complexed with GDPPCP
Descriptor: Cell division protein FtsZ, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, POTASSIUM ION
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2021-05-24
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
6KVQ
DownloadVisualize
BU of 6kvq by Molmil
S. aureus FtsZ in complex with BOFP (compound 3)
Descriptor: CALCIUM ION, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Ferrer-Gonzalez, E, Fujita, J, Yoshizawa, T, Nelson, J.M, Pilch, A.J, Hillman, E, Ozawa, M, Kuroda, N, Parhi, A.K, LaVoie, E.J, Matsumura, H, Pilch, D.S.
Deposit date:2019-09-05
Release date:2020-01-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure-Guided Design of a Fluorescent Probe for the Visualization of FtsZ in Clinically Important Gram-Positive and Gram-Negative Bacterial Pathogens.
Sci Rep, 9, 2019
7OHN
DownloadVisualize
BU of 7ohn by Molmil
SaFtsZ complexed with GDP, AlF4- and Mg2+
Descriptor: Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2021-05-11
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
7OJZ
DownloadVisualize
BU of 7ojz by Molmil
SaFtsZ complexed with GMPCP
Descriptor: 1,2-ETHANEDIOL, Cell division protein FtsZ, PHOSPHOMETHYLPHOSPHONIC ACID GUANOSYL ESTER, ...
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2021-05-17
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
6Y1U
DownloadVisualize
BU of 6y1u by Molmil
Mycobacterium tuberculosis FtsZ-GDP in complex with 4-hydroxycoumarin
Descriptor: 4-HYDROXY-2H-CHROMEN-2-ONE, Cell division protein FtsZ, DIMETHYL SULFOXIDE, ...
Authors:Alnami, A.T, Norton, R.S, Pena, H.P, Haider, M, kozielski, F.
Deposit date:2020-02-13
Release date:2021-06-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Conformational Flexibility of A Highly Conserved Helix Controls Cryptic Pocket Formation in FtsZ.
J.Mol.Biol., 433, 2021
7ON2
DownloadVisualize
BU of 7on2 by Molmil
SaFtsZ complexed with GDP (soaking in 10 mM CyDTA)
Descriptor: 1,2-ETHANEDIOL, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2021-05-25
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
7YYQ
DownloadVisualize
BU of 7yyq by Molmil
Molecular snapshots of drug release from tubulin: Dark state
Descriptor: Azo-Combretastatin A4 (cis), CALCIUM ION, Designed Ankyrin Repeat Protein (DARPIN) D1, ...
Authors:Wranik, M, Weinert, T, Standfuss, J.
Deposit date:2022-02-18
Release date:2023-02-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Watching the release of a photopharmacological drug from tubulin using time-resolved serial crystallography.
Nat Commun, 14, 2023
5XDV
DownloadVisualize
BU of 5xdv by Molmil
Staphylococcus aureus FtsZ 12-316 G196S complexed with TXA6101
Descriptor: 3-[[5-bromanyl-4-[4-(trifluoromethyl)phenyl]-1,3-oxazol-2-yl]methoxy]-2,6-bis(fluoranyl)benzamide, CALCIUM ION, Cell division protein FtsZ, ...
Authors:Fujita, J, Maeda, Y, Mizohata, E, Inoue, T, Kaul, M, Parhi, A.K, LaVoie, E.J, Pilch, D.S, Matsumura, H.
Deposit date:2017-03-30
Release date:2017-08-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Flexibility of an Inhibitor Overcomes Drug Resistance Mutations in Staphylococcus aureus FtsZ
ACS Chem. Biol., 12, 2017
5H5H
DownloadVisualize
BU of 5h5h by Molmil
Staphylococcus aureus FtsZ-GDP R29A mutant in T state
Descriptor: CALCIUM ION, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE
Authors:Fujita, J, Harada, R, Maeda, Y, Saito, Y, Mizohata, E, Inoue, T, Shigeta, Y, Matsumura, H.
Deposit date:2016-11-05
Release date:2017-05-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Identification of the key interactions in structural transition pathway of FtsZ from Staphylococcus aureus
J. Struct. Biol., 198, 2017

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon