5XDT

Staphylococcus aureus FtsZ 12-316 complexed with TXA707

Summary for 5XDT

Entry DOI	10.2210/pdb5xdt/pdb
Related	5XDU 5XDV 5XDW
Descriptor	Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... (6 entities in total)
Functional Keywords	cell division, gtpase, inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Staphylococcus aureus (strain MRSA252)
Cellular location	Cytoplasm : Q6GHP9
Total number of polymer chains	1
Total formula weight	32923.87
Authors	Fujita, J.,Maeda, Y.,Mizohata, E.,Inoue, T.,Kaul, M.,Parhi, A.K.,LaVoie, E.J.,Pilch, D.S.,Matsumura, H. (deposition date: 2017-03-30, release date: 2017-08-02, Last modification date: 2023-11-22)
Primary citation	Fujita, J.,Maeda, Y.,Mizohata, E.,Inoue, T.,Kaul, M.,Parhi, A.K.,LaVoie, E.J.,Pilch, D.S.,Matsumura, H. Structural Flexibility of an Inhibitor Overcomes Drug Resistance Mutations in Staphylococcus aureus FtsZ ACS Chem. Biol., 12:1947-1955, 2017 Cited by PubMed: 28621933 DOI: 10.1021/acschembio.7b00323 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.3 Å)

Structure validation