5XDV
Staphylococcus aureus FtsZ 12-316 G196S complexed with TXA6101
Summary for 5XDV
| Entry DOI | 10.2210/pdb5xdv/pdb |
| Related | 5XDT 5XDU 5XDW |
| Descriptor | Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... (5 entities in total) |
| Functional Keywords | cell division, gtpase, inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Staphylococcus aureus (strain MRSA252) |
| Cellular location | Cytoplasm : Q6GHP9 |
| Total number of polymer chains | 1 |
| Total formula weight | 32843.51 |
| Authors | Fujita, J.,Maeda, Y.,Mizohata, E.,Inoue, T.,Kaul, M.,Parhi, A.K.,LaVoie, E.J.,Pilch, D.S.,Matsumura, H. (deposition date: 2017-03-30, release date: 2017-08-02, Last modification date: 2023-11-22) |
| Primary citation | Fujita, J.,Maeda, Y.,Mizohata, E.,Inoue, T.,Kaul, M.,Parhi, A.K.,LaVoie, E.J.,Pilch, D.S.,Matsumura, H. Structural Flexibility of an Inhibitor Overcomes Drug Resistance Mutations in Staphylococcus aureus FtsZ ACS Chem. Biol., 12:1947-1955, 2017 Cited by PubMed: 28621933DOI: 10.1021/acschembio.7b00323 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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