121P | | STRUKTUR UND GUANOSINTRIPHOSPHAT-HYDROLYSEMECHANISMUS DES C-TERMINAL VERKUERZTEN MENSCHLICHEN KREBSPROTEINS P21-H-RAS | | Descriptor: | H-RAS P21 PROTEIN, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | | Authors: | Krengel, U., Scheffzek, K., Scherer, A., Kabsch, W., Wittinghofer, A., Pai, E.F. | | Deposit date: | 1991-06-06 | | Release date: | 1994-01-31 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | Struktur Und Guanosintriphosphat-Hydrolysemechanismus Des C-Terminal Verkuerzten Menschlichen Krebsproteins P21-H-Ras
Thesis, 1991
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1A2B | | HUMAN RHOA COMPLEXED WITH GTP ANALOGUE | | Descriptor: | TRANSFORMING PROTEIN RHOA, MAGNESIUM ION, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE | | Authors: | Ihara, K., Muraguchi, S., Kato, M., Shimizu, T., Shirakawa, M., Kuroda, S., Kaibuchi, K., Hakoshima, T. | | Deposit date: | 1997-12-26 | | Release date: | 1998-06-17 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue.
J.Biol.Chem., 273, 1998
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1A4R | | G12V MUTANT OF HUMAN PLACENTAL CDC42 GTPASE IN THE GDP FORM | | Descriptor: | G25K GTP-BINDING PROTEIN, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Rudolph, M.G., Vetter, I.R., Wittinghofer, A. | | Deposit date: | 1998-02-02 | | Release date: | 1999-03-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Nucleotide binding to the G12V-mutant of Cdc42 investigated by X-ray diffraction and fluorescence spectroscopy: two different nucleotide states in one crystal.
Protein Sci., 8, 1999
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1AA9 | | HUMAN C-HA-RAS(1-171)(DOT)GDP, NMR, MINIMIZED AVERAGE STRUCTURE | | Descriptor: | C-HA-RAS, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE | | Authors: | Ito, Y., Yamasaki, Y., Muto, Y., Kawai, G., Nishimura, S., Miyazawa, T., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 1997-01-27 | | Release date: | 1997-07-29 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Regional polysterism in the GTP-bound form of the human c-Ha-Ras protein.
Biochemistry, 36, 1997
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1AGP | | THREE-DIMENSIONAL STRUCTURES AND PROPERTIES OF A TRANSFORMING AND A NONTRANSFORMING GLY-12 MUTANT OF P21-H-RAS | | Descriptor: | C-H-RAS P21 PROTEIN, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | | Authors: | Franken, S.M., Scheidig, A.J., Wittinghofer, A., Goody, R.S. | | Deposit date: | 1993-03-29 | | Release date: | 1994-04-30 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Three-dimensional structures and properties of a transforming and a nontransforming glycine-12 mutant of p21H-ras.
Biochemistry, 32, 1993
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1AJE | | CDC42 FROM HUMAN, NMR, 20 STRUCTURES | | Descriptor: | CDC42HS | | Authors: | Feltham, J.L., Dotsch, V., Raza, S., Manor, D., Cerione, R.A., Sutcliffe, M.J., Wagner, G., Oswald, R.E. | | Deposit date: | 1997-05-02 | | Release date: | 1997-11-12 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Definition of the switch surface in the solution structure of Cdc42Hs.
Biochemistry, 36, 1997
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1AN0 | | CDC42HS-GDP COMPLEX | | Descriptor: | CDC42HS-GDP, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE | | Authors: | Kongsaeree, P., Cerione, R., Clardy, J. | | Deposit date: | 1997-06-26 | | Release date: | 1999-01-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The Structure Determination of Cdc42Hs and Gdp Complex
To be Published
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1BYU | | CANINE GDP-RAN | | Descriptor: | PROTEIN (GTP-BINDING PROTEIN RAN), MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE | | Authors: | Stewart, M., Kent, H.M., Mccoy, A.J. | | Deposit date: | 1998-10-18 | | Release date: | 1998-12-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | The structure of the Q69L mutant of GDP-Ran shows a major conformational change in the switch II loop that accounts for its failure to bind nuclear transport factor 2 (NTF2).
J.Mol.Biol., 284, 1998
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1CEE | | SOLUTION STRUCTURE OF CDC42 IN COMPLEX WITH THE GTPASE BINDING DOMAIN OF WASP | | Descriptor: | GTP-BINDING RHO-LIKE PROTEIN, WISKOTT-ALDRICH SYNDROME PROTEIN WASP, MAGNESIUM ION, ... | | Authors: | Abdul-Manan, N., Aghazadeh, B., Liu, G.A., Majumdar, A., Ouerfelli, O., Rosen, M.K. | | Deposit date: | 1999-03-08 | | Release date: | 1999-06-30 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' protein.
Nature, 399, 1999
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1CF4 | | CDC42/ACK GTPASE-BINDING DOMAIN COMPLEX | | Descriptor: | PROTEIN (CDC42 HOMOLOG), PROTEIN (ACTIVATED P21CDC42HS KINASE), MAGNESIUM ION, ... | | Authors: | Mott, H.R., Owen, D., Nietlispach, D., Lowe, P.N., Lim, L., Laue, E.D. | | Deposit date: | 1999-03-23 | | Release date: | 1999-06-18 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK.
Nature, 399, 1999
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1CLU | | H-RAS COMPLEXED WITH DIAMINOBENZOPHENONE-BETA,GAMMA-IMIDO-GTP | | Descriptor: | TRANSFORMING PROTEIN P21/H-RAS-1, MAGNESIUM ION, 3-AMINOBENZOPHENONE-4-YL-AMINOHYDROXYPHOSPHINYLAMINOPHOSPHONIC ACID-GUANYLATE ESTER | | Authors: | Ahmadian, M.R., Zor, T., Vogt, D., Kabsch, W., Selinger, Z., Wittinghofer, A., Scheffzek, K. | | Deposit date: | 1999-05-03 | | Release date: | 1999-05-28 | | Last modified: | 2019-11-27 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Guanosine triphosphatase stimulation of oncogenic Ras mutants.
Proc.Natl.Acad.Sci.USA, 96, 1999
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1CRP | | THE SOLUTION STRUCTURE AND DYNAMICS OF RAS P21. GDP DETERMINED BY HETERONUCLEAR THREE AND FOUR DIMENSIONAL NMR SPECTROSCOPY | | Descriptor: | C-H-RAS P21 PROTEIN, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE | | Authors: | Kraulis, P.J., Domaille, P.J., Campbell-Burk, S.L., Van Aken, T., Laue, E.D. | | Deposit date: | 1993-11-24 | | Release date: | 1994-07-31 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution structure and dynamics of ras p21.GDP determined by heteronuclear three- and four-dimensional NMR spectroscopy.
Biochemistry, 33, 1994
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1CRQ | | THE SOLUTION STRUCTURE AND DYNAMICS OF RAS P21. GDP DETERMINED BY HETERONUCLEAR THREE AND FOUR DIMENSIONAL NMR SPECTROSCOPY | | Descriptor: | C-H-RAS P21 PROTEIN, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE | | Authors: | Kraulis, P.J., Domaille, P.J., Campbell-Burk, S.L., Van Aken, T., Laue, E.D. | | Deposit date: | 1993-11-24 | | Release date: | 1994-07-31 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution structure and dynamics of ras p21.GDP determined by heteronuclear three- and four-dimensional NMR spectroscopy.
Biochemistry, 33, 1994
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1CRR | | THE SOLUTION STRUCTURE AND DYNAMICS OF RAS P21. GDP DETERMINED BY HETERONUCLEAR THREE AND FOUR DIMENSIONAL NMR SPECTROSCOPY | | Descriptor: | C-H-RAS P21 PROTEIN, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE | | Authors: | Kraulis, P.J., Domaille, P.J., Campbell-Burk, S.L., Van Aken, T., Laue, E.D. | | Deposit date: | 1993-11-24 | | Release date: | 1994-07-31 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution structure and dynamics of ras p21.GDP determined by heteronuclear three- and four-dimensional NMR spectroscopy.
Biochemistry, 33, 1994
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1CTQ | | STRUCTURE OF P21RAS IN COMPLEX WITH GPPNHP AT 100 K | | Descriptor: | PROTEIN (TRANSFORMING PROTEIN P21/H-RAS-1), MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | | Authors: | Scheidig, A., Burmester, C., Goody, R.S. | | Deposit date: | 1999-08-20 | | Release date: | 1999-11-15 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (1.26 Å) | | Cite: | The pre-hydrolysis state of p21(ras) in complex with GTP: new insights into the role of water molecules in the GTP hydrolysis reaction of ras-like proteins.
Structure Fold.Des., 7, 1999
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1CXZ | | CRYSTAL STRUCTURE OF HUMAN RHOA COMPLEXED WITH THE EFFECTOR DOMAIN OF THE PROTEIN KINASE PKN/PRK1 | | Descriptor: | PROTEIN (HIS-TAGGED TRANSFORMING PROTEIN RHOA(0-181)), PROTEIN (PKN), MAGNESIUM ION, ... | | Authors: | Maesaki, R., Ihara, K., Shimizu, T., Kuroda, S., Kaibuchi, K., Hakoshima, T. | | Deposit date: | 1999-08-31 | | Release date: | 1999-10-08 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1.
Mol.Cell, 4, 1999
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1DPF | | CRYSTAL STRUCTURE OF A MG-FREE FORM OF RHOA COMPLEXED WITH GDP | | Descriptor: | RHOA, GUANOSINE-5'-DIPHOSPHATE | | Authors: | Shimizu, T., Ihara, K., Maesaki, R., Kuroda, S., Kaibuchi, K., Hakoshima, T. | | Deposit date: | 1999-12-27 | | Release date: | 2000-06-21 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | An open conformation of switch I revealed by the crystal structure of a Mg2+-free form of RHOA complexed with GDP. Implications for the GDP/GTP exchange mechanism.
J.Biol.Chem., 275, 2000
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1DS6 | | CRYSTAL STRUCTURE OF A RAC-RHOGDI COMPLEX | | Descriptor: | RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2, RHO GDP-DISSOCIATION INHIBITOR 2, MAGNESIUM ION, ... | | Authors: | Scheffzek, K., Stephan, I., Jensen, O.N., Illenberger, D., Gierschik, P. | | Deposit date: | 2000-01-07 | | Release date: | 2000-07-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | The Rac-RhoGDI complex and the structural basis for the regulation of Rho proteins by RhoGDI.
Nat.Struct.Biol., 7, 2000
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1E0A | | CDC42 COMPLEXED WITH THE GTPASE BINDING DOMAIN OF P21 ACTIVATED KINASE | | Descriptor: | Cell division control protein 42 homolog, Serine/threonine-protein kinase PAK 1, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | Authors: | Morreale, A., Venkatesan, M., Mott, H.R., Owen, D., Nietlispach, D., Lowe, P.N., Laue, E.D. | | Deposit date: | 2000-03-16 | | Release date: | 2000-04-18 | | Last modified: | 2019-09-25 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of Cdc42 Bound to the Gtpase Binding Domian of Pak
Nat.Struct.Biol., 7, 2000
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1EES | | SOLUTION STRUCTURE OF CDC42HS COMPLEXED WITH A PEPTIDE DERIVED FROM P-21 ACTIVATED KINASE, NMR, 20 STRUCTURES | | Descriptor: | GTP-BINDING PROTEIN, P21-ACTIVATED KINASE | | Authors: | Gizachew, D., Guo, W., Chohan, K.C., Sutcliffe, M.J., Oswald, R.E. | | Deposit date: | 2000-02-02 | | Release date: | 2000-03-29 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Structure of the complex of Cdc42Hs with a peptide derived from P-21 activated kinase.
Biochemistry, 39, 2000
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1EK0 | | GPPNHP-BOUND YPT51 AT 1.48 A RESOLUTION | | Descriptor: | PROTEIN (GTP-BINDING PROTEIN YPT51), MAGNESIUM ION, NICKEL (II) ION, ... | | Authors: | Esters, H., Scheidig, A.J. | | Deposit date: | 2000-03-06 | | Release date: | 2000-04-17 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (1.48 Å) | | Cite: | High-resolution crystal structure of S. cerevisiae Ypt51(DeltaC15)-GppNHp, a small GTP-binding protein involved in regulation of endocytosis.
J.Mol.Biol., 298, 2000
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1FTN | | CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX | | Descriptor: | TRANSFORMING PROTEIN RHOA (H12), MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE | | Authors: | Wei, Y., Zhang, Y., Derewenda, U., Liu, X., Minor, W., Nakamoto, R.K., Somlyo, A.V., Somlyo, A.P., Derewenda, Z.S. | | Deposit date: | 1997-03-13 | | Release date: | 1998-03-18 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of RhoA-GDP and its functional implications.
Nat.Struct.Biol., 4, 1997
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1G16 | | CRYSTAL STRUCTURE OF SEC4-GDP | | Descriptor: | RAS-RELATED PROTEIN SEC4, COBALT (II) ION, GUANOSINE-5'-DIPHOSPHATE | | Authors: | Stroupe, C., Brunger, A.T. | | Deposit date: | 2000-10-10 | | Release date: | 2000-12-11 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structures of a Rab protein in its inactive and active conformations.
J.Mol.Biol., 304, 2000
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1G17 | |
1GNP | | X-RAY CRYSTAL STRUCTURE ANALYSIS OF THE CATALYTIC DOMAIN OF THE ONCOGENE PRODUCT P21H-RAS COMPLEXED WITH CAGED GTP AND MANT DGPPNHP | | Descriptor: | C-H-RAS P21 PROTEIN, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID 3'-O-(N-METHYLANTHRANILOYL-2'-DEOXYGUANYLATE ESTER | | Authors: | Scheidig, A., Franken, S.M., Corrie, J.E.T., Reid, G.P., Wittinghofer, A., Pai, E.F., Goody, R.S. | | Deposit date: | 1995-05-11 | | Release date: | 1995-07-31 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | X-ray crystal structure analysis of the catalytic domain of the oncogene product p21H-ras complexed with caged GTP and mant dGppNHp.
J.Mol.Biol., 253, 1995
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