6DLW
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COMPLEMENT COMPONENT POLYC9
Descriptor:Complement component C9, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE
Authors:Dunstone, M.A., Spicer, B.A., Law, R.H.P.
Deposit date:2018-06-03
Release date:2018-09-12
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:The first transmembrane region of complement component-9 acts as a brake on its self-assembly.
Nat Commun, 9, 2018
6CXO
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COMPLEMENT COMPONENT-9
Descriptor:Complement component C9, ZINC ION, CALCIUM ION, ...
Authors:Law, R.H.P., Spicer, B.A., Caradoc-Davies, T.T.
Deposit date:2018-04-03
Release date:2018-09-05
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The first transmembrane region of complement component-9 acts as a brake on its self-assembly.
Nat Commun, 9, 2018
6BYV
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SOLUTION NMR STRUCTURE OF CYSTEINE-RICH CALCIUM BOUND DOMAINS OF VERY LOW DENSITY LIPOPROTEIN RECEPTOR
Descriptor:Very low-density lipoprotein receptor, CALCIUM ION
Authors:Banerjee, K., Gruschus, J.M., Tjandra, N., Yakovlev, S., Medved, L.
Deposit date:2017-12-21
Release date:2018-07-18
Last modified:2018-08-08
Method:SOLUTION NMR
Cite:Nuclear Magnetic Resonance Solution Structure of the Recombinant Fragment Containing Three Fibrin-Binding Cysteine-Rich Domains of the Very Low Density Lipoprotein Receptor.
Biochemistry, 57, 2018
5OYL
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VSV G CR2
Descriptor:Glycoprotein, Low-density lipoprotein receptor, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Albertini, A.A., Belot, L., Legrand, P., Gaudin, Y.
Deposit date:2017-09-11
Release date:2018-03-21
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for the recognition of LDL-receptor family members by VSV glycoprotein.
Nat Commun, 9, 2018
5M3L
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SINGLE-PARTICLE CRYO-EM USING ALIGNMENT BY CLASSIFICATION (ABC): THE STRUCTURE OF LUMBRICUS TERRESTRIS HEMOGLOBIN
Descriptor:Extracellular globin-4, Extracellular globin-2, Extracellular globin-3, ...
Authors:Afanasyev, P., Linnemayr-Seer, C., Ravelli, R.B.G., Matadeen, R., De Carlo, S., Alewijnse, B., Portugal, R.V., Pannu, N.S., Schatz, M., van Heel, M.
Deposit date:2016-10-15
Release date:2017-09-13
Last modified:2018-10-17
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Single-particle cryo-EM using alignment by classification (ABC): the structure of Lumbricus terrestris haemoglobin.
IUCrJ, 4, 2017
5O32
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THE STRUCTURE OF COMPLEMENT COMPLEX
Descriptor:Complement C3, Complement factor H,Complement factor H, Complement factor I, ...
Authors:Xue, X., Wu, J., Forneris, F., Gros, P.
Deposit date:2017-05-23
Release date:2017-06-28
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (4.206209 Å)
Cite:Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses.
Nat. Struct. Mol. Biol., 24, 2017
5B4X
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CRYSTAL STRUCTURE OF THE APOER2 ECTODOMAIN IN COMPLEX WITH THE REELIN R56 FRAGMENT
Descriptor:Reelin, Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor, ...
Authors:Yasui, N., Hirai, H., Yamashita, K., Takagi, J., Nogi, T.
Deposit date:2016-04-20
Release date:2017-04-26
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of the ectodomain from a LDLR close homologue in complex with its physiological ligand.
To Be Published
5B4Y
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CRYSTAL STRUCTURE OF THE LA12 FRAGMENT OF APOER2
Descriptor:Low-density lipoprotein receptor-related protein 8, CALCIUM ION
Authors:Nogi, T., Tabata, S., Hirai, H., Yasui, N., Takagi, J.
Deposit date:2016-04-20
Release date:2017-04-26
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the ectodomain from a LDLR close homologue in complex with its physiological ligand.
To Be Published
5H7V
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STRUCTURE OF FULL-LENGTH EXTRACELLULAR DOMAIN OF HAI-1 AT PH 4.6
Descriptor:Kunitz-type protease inhibitor 1
Authors:Liu, M., Huang, M.
Deposit date:2016-11-21
Release date:2017-03-29
Last modified:2017-05-31
Method:X-RAY DIFFRACTION (3.82 Å)
Cite:The crystal structure of a multidomain protease inhibitor (HAI-1) reveals the mechanism of its auto-inhibition
J. Biol. Chem., 292, 2017
4ZRP
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TC:CD320
Descriptor:Transcobalamin-2, CD320 antigen, CO-CYANOCOBALAMIN, ...
Authors:Alam, A., Locher, K.P.
Deposit date:2015-05-12
Release date:2016-07-20
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of transcobalamin recognition by human CD320 receptor.
Nat Commun, 7, 2016
4ZRQ
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E88 DELETION MUTANT OF CD320 IN COMPLEX WITH TC2
Descriptor:Transcobalamin-2, CD320 antigen, CO-CYANOCOBALAMIN, ...
Authors:Alam, A., Locher, K.P.
Deposit date:2015-05-12
Release date:2016-07-20
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of transcobalamin recognition by human CD320 receptor.
Nat Commun, 7, 2016
5FMW
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THE POLY-C9 COMPONENT OF THE COMPLEMENT MEMBRANE ATTACK COMPLEX
Descriptor:POLYC9
Authors:Dudkina, N.V., Spicer, B.A., Reboul, C.F., Conroy, P.J., Lukoyanova, N., Elmlund, H., Law, R.H.P., Ekkel, S.M., Kondos, S.C., Goode, R.J.A., Ramm, G., Whisstock, J.C., Saibil, H.R., Dunstone, M.A.
Deposit date:2015-11-10
Release date:2016-02-17
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Structure of the Poly-C9 Component of the Complement Membrane Attack Complex
Nat.Commun., 7, 2016
4U8U
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THE CRYSTALLOGRAPHIC STRUCTURE OF THE GIANT HEMOGLOBIN FROM GLOSSOSCOLEX PAULISTUS AT 3.2 A RESOLUTION.
Descriptor:Globin a chain, Globin b Chain, Globin c Chain, ...
Authors:Bachega, J.F.R., Maluf, F.V., Andi, B., D'Muniz Pereira, H., Carazzollea, M.F., Orville, A., Tabak, M., Garratt, R.C., Horjales, E.
Deposit date:2014-08-04
Release date:2015-06-10
Last modified:2016-09-07
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The structure of the giant haemoglobin from Glossoscolex paulistus.
Acta Crystallogr.,Sect.D, 71, 2015
4V93
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FITTED COORDINATES FOR LUMBRICUS TERRESTRIS HEMOGLOBIN CRYO-EM COMPLEX (EMD-2627)
Descriptor:EXTRACELLULAR GLOBIN-3, HEMOGLOBIN CHAIN D1, EXTRACELLULAR GLOBIN-4, ...
Authors:Chen, W.T., Chen, Y.C., Liou, H.H., Chao, C.Y.
Deposit date:2014-04-16
Release date:2014-07-09
Last modified:2014-12-10
Method:ELECTRON MICROSCOPY (8.1 Å)
Cite:Structural Basis for Cooperative Oxygen Binding and Bracelet-Assisted Assembly of Lumbricus Terrestris Hemoglobin
To be Published
2M96
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SOLUTION NMR STRUCTURE OF THE RXFP2 LDLA MODULE
Descriptor:Relaxin receptor 2, CALCIUM ION
Authors:Petrie, E.J., Gooley, P.R., Bathgate, A.D.
Deposit date:2013-06-03
Release date:2014-06-04
Method:SOLUTION NMR
Cite:Solution NMR structure of the RXFP2 LDLa module
To be Published
2M0P
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SOLUTION STRUCTURE OF THE TENTH COMPLEMENT TYPE REPEAT OF HUMAN MEGALIN
Descriptor:Low-density lipoprotein receptor-related protein 2, CALCIUM ION
Authors:Dagil, R., Kragelund, B.
Deposit date:2012-11-01
Release date:2013-01-09
Last modified:2013-06-19
Method:SOLUTION NMR
Cite:Gentamicin binds to the megalin receptor as a competitive inhibitor using the common ligand binding motif of complement type repeats: insight from the nmr structure of the 10th complement type repeat domain alone and in complex with gentamicin.
J.Biol.Chem., 288, 2013
4E0S
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CRYSTAL STRUCTURE OF C5B-6
Descriptor:Complement C5, Complement component C6, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Aleshin, A.E., Stec, B., DiScipio, R., Liddington, R.C.
Deposit date:2012-03-05
Release date:2012-04-18
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (4.21 Å)
Cite:Crystal structure of c5b-6 suggests structural basis for priming assembly of the membrane attack complex.
J.Biol.Chem., 287, 2012
4A5W
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CRYSTAL STRUCTURE OF C5B6
Descriptor:COMPLEMENT C5, COMPLEMENT COMPONENT C6, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Hadders, M.A., Bubeck, D., Forneris, F., Pangburn, M., Llorca, O., Lea, S.M., Gros, P.
Deposit date:2011-10-28
Release date:2012-03-14
Last modified:2012-10-31
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5B6 and Sc5B9.
Cell Rep., 1, 2012
3T5O
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CRYSTAL STRUCTURE OF HUMAN COMPLEMENT COMPONENT C6
Descriptor:Complement component C6, CADMIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Aleshin, A.E., Stec, B., Bankston, L.A., DiScipio, R.G., Liddington, R.C.
Deposit date:2011-07-27
Release date:2012-02-01
Last modified:2012-04-11
Method:X-RAY DIFFRACTION (2.869 Å)
Cite:Structure of Complement C6 Suggests a Mechanism for Initiation and Unidirectional, Sequential Assembly of Membrane Attack Complex (MAC).
J.Biol.Chem., 287, 2012
2LGP
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SOLUTION STRUCTURE OF LA45 FROM LDLR
Descriptor:Low-density lipoprotein receptor, CALCIUM ION
Authors:Guttman, M., Komives, E.A.
Deposit date:2011-08-01
Release date:2011-11-30
Last modified:2012-01-04
Method:SOLUTION NMR
Cite:The Structure, Dynamics, and Binding of the LA45 Module Pair of the Low-Density Lipoprotein Receptor Suggest an Important Role for LA4 in Ligand Release.
Biochemistry, 50, 2011
2XRC
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HUMAN COMPLEMENT FACTOR I
Descriptor:HUMAN COMPLEMENT FACTOR I, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE
Authors:Roversi, P., Johnson, S., Lea, S.M.
Deposit date:2010-09-13
Release date:2011-07-13
Last modified:2011-08-17
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Structural Basis for Complement Factor I Control and its Disease-Associated Sequence Polymorphisms.
Proc.Natl.Acad.Sci.USA, 108, 2011
3OJY
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CRYSTAL STRUCTURE OF HUMAN COMPLEMENT COMPONENT C8
Descriptor:Complement component C8 alpha chain, Complement component C8 beta chain, Complement component C8 gamma chain, ...
Authors:Lovelace, L.L., Cooper, C.L., Sodetz, J.M., Lebioda, L.
Deposit date:2010-08-23
Release date:2011-04-13
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement.
J.Biol.Chem., 286, 2011
3M0C
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THE X-RAY CRYSTAL STRUCTURE OF PCSK9 IN COMPLEX WITH THE LDL RECEPTOR
Descriptor:Proprotein convertase subtilisin/kexin type 9, Low-density lipoprotein receptor, CALCIUM ION
Authors:Spraggon, G., Hampton, E.N.
Deposit date:2010-03-02
Release date:2011-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (7.01 Å)
Cite:The X-ray Crystal Structure of PCSK9 in Complex with the LDL receptor
To be Published
2KNX
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SOLUTION STRUCTURE OF COMPLEMENT REPEAT CR17 FROM LRP-1
Descriptor:Prolow-density lipoprotein receptor-related protein 1, CALCIUM ION
Authors:Guttman, M., Komives, E.
Deposit date:2009-09-07
Release date:2010-04-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the minimal interface between ApoE and LRP.
J.Mol.Biol., 398, 2010
2KNY
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FUSION CONSTRUCT OF CR17 FROM LRP-1 AND APOE RESIDUES 130-149
Descriptor:LRP-1, linker, Apo-E, ...
Authors:Guttman, M., Komives, E.A.
Deposit date:2009-09-08
Release date:2010-04-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the minimal interface between ApoE and LRP.
J.Mol.Biol., 398, 2010
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