8JXE

rat megalin RAP complex head

Summary for 8JXE

Entry DOI	10.2210/pdb8jxe/pdb
EMDB information	36663 36698
Descriptor	LDL receptor related protein 2, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (14 entities in total)
Functional Keywords	endocytosis receptor, endocytosis
Biological source	Rattus norvegicus (Norway rat) More
Total number of polymer chains	10
Total formula weight	1056166.78
Authors	Goto, S.,Tsutsumi, A.,Lee, Y.,Hosojima, M.,Kabasawa, H.,Komochi, K.,Yun-san, L.,Nagatoshi, S.,Tsumoto, K.,Nishizawa, T.,Kikkawa, M.,Saito, A. (deposition date: 2023-06-30, release date: 2024-06-19)
Primary citation	Goto, S.,Tsutsumi, A.,Lee, Y.,Hosojima, M.,Kabasawa, H.,Komochi, K.,Nagatoishi, S.,Takemoto, K.,Tsumoto, K.,Nishizawa, T.,Kikkawa, M.,Saito, A. Cryo-EM structures elucidate the multiligand receptor nature of megalin. Proc.Natl.Acad.Sci.USA, 121:e2318859121-e2318859121, 2024 Cited by PubMed: 38771880 DOI: 10.1073/pnas.2318859121 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation