PDB: 109 件ウェブページステータス検索Chemie searchBIRD

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2Q3Z	Transglutaminase 2 undergoes large conformational change upon activation 分子名称: Polypeptide, SULFATE ION, Transglutaminase 2 著者 Strop, P, Pinkas, D.M, Brunger, A.T, Khosla, C. 登録日 2007-05-30 公開日 2007-10-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Transglutaminase 2 undergoes a large conformational change upon activation Plos Biol., 5, 2007
3TW5	Crystal structure of the GP42 transglutaminase from Phytophthora sojae 分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Transglutaminase elicitor 著者 Reiss, K, Kirchner, E, Zocher, G, Stehle, T. 登録日 2011-09-21 公開日 2011-10-12 最終更新日 2020-10-21 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Structural and Phylogenetic Analyses of the GP42 Transglutaminase from Phytophthora sojae Reveal an Evolutionary Relationship between Oomycetes and Marine Vibrio Bacteria. J.Biol.Chem., 286, 2011
8OXW	Transglutaminase 3 in complex with DH patient-derived Fab DH63-B02 分子名称: 1,2-ETHANEDIOL, Antibody fab fragment heavy chain, Antibody fab fragment light chain, ... 著者 Heggelund, J.E, Sollid, L.M. 登録日 2023-05-02 公開日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Autoantibody binding and unique enzyme-substrate intermediate conformation of human transglutaminase 3. Nat Commun, 14, 2023
8OXX	Transglutaminase 3 in complex with inhibitor Z-don and DH patient-derived Fab DH63-B02 分子名称: 1,2-ETHANEDIOL, 5-OXO-L-NORLEUCINE, Antibody fab fragment heavy chain, ... 著者 Heggelund, J.E, Sollid, L.M. 登録日 2023-05-02 公開日 2023-10-18 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Autoantibody binding and unique enzyme-substrate intermediate conformation of human transglutaminase 3. Nat Commun, 14, 2023
8OXV	Transglutaminase 3 zymogen in complex with DH patient-derived Fab DH63-B02 分子名称: 1,2-ETHANEDIOL, Antibody Fab fragment Heavy chain, Antibody Fab fragment light chain, ... 著者 Heggelund, J.E, Sollid, L.M. 登録日 2023-05-02 公開日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Autoantibody binding and unique enzyme-substrate intermediate conformation of human transglutaminase 3. Nat Commun, 14, 2023
8OXY	Transglutaminase 3 without calcium in complex with DH patient-derived Fab DH63-B02 分子名称: 1,2-ETHANEDIOL, Antibody fab fragment heavy chain, Antibody fab fragment light chain, ... 著者 Heggelund, J.E, Sollid, L.M. 登録日 2023-05-02 公開日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Autoantibody binding and unique enzyme-substrate intermediate conformation of human transglutaminase 3. Nat Commun, 14, 2023
1IU4	Crystal Structure Analysis of the Microbial Transglutaminase 分子名称: microbial transglutaminase 著者 Kashiwagi, T, Yokoyama, K, Ishikawa, K, Ono, K, Ejima, D, Matsui, H, Suzuki, E. 登録日 2002-02-27 公開日 2002-08-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of microbial transglutaminase from Streptoverticillium mobaraense J.Biol.Chem., 277, 2002
6A8P	Transglutaminase 2 mutant G224V in complex with GTP 分子名称: GUANOSINE-5'-TRIPHOSPHATE, Protein-glutamine gamma-glutamyltransferase 2 著者 Park, H.H, Ha, H.J, Kwon, S. 登録日 2018-07-09 公開日 2018-09-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.537 Å) 主引用文献 Structure of natural variant transglutaminase 2 reveals molecular basis of gaining stability and higher activity. PLoS ONE, 13, 2018
3LY6	Crystal structure of human transglutaminase 2 complex with adenosine 5' Triphosphate 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Protein-glutamine gamma-glutamyltransferase 2 著者 Han, B.G, Lee, B.I. 登録日 2010-02-26 公開日 2010-08-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.14 Å) 主引用文献 Crystal structure of human transglutaminase 2 in complex with adenosine triphosphate Int.J.Biol.Macromol., 47, 2010
7C9J	Transglutaminase from Geobacillus stearothermophilus (without C-terminal extension) 分子名称: 1,2-ETHANEDIOL, CITRIC ACID, Protein-glutamine gamma-glutamyltransferase 著者 Takita, T, Mikami, B, Lei, Y, Jing, Y, Yamada, A, Yasukawa, K. 登録日 2020-06-06 公開日 2021-06-09 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Transglutaminase from Geobacillus stearothermophilus (without C-terminal extension) To be published
4P8I	Tgl - a bacterial spore coat transglutaminase 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Brito, J.A, Placido, D, Fernandes, C, Lousa, D, Isidro, A, Soares, C.M, Pohl, J, Carrondo, M.A, Henriques, A.O, Archer, M. 登録日 2014-03-31 公開日 2015-09-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural and Functional Characterization of an Ancient Bacterial Transglutaminase Sheds Light on the Minimal Requirements for Protein Cross-Linking. Biochemistry, 54, 2015
4PA5	Tgl - a bacterial spore coat transglutaminase - cystamine complex 分子名称: 1,2-ETHANEDIOL, 2-AMINO-ETHANETHIOL, CITRATE ANION, ... 著者 Brito, J.A, Placido, D, Fernandes, C.G, Lousa, D, Isidro, A, Soares, C.M, Pohl, J, Carrondo, M.A, Henriques, A.O, Archer, M. 登録日 2014-04-07 公開日 2015-09-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Structural and Functional Characterization of an Ancient Bacterial Transglutaminase Sheds Light on the Minimal Requirements for Protein Cross-Linking. Biochemistry, 54, 2015
3S3P	Transglutaminase 2 in complex with a novel inhibitor 分子名称: Peptide inhibitor, Protein-glutamine gamma-glutamyltransferase 2, SULFATE ION 著者 Lindemann, I, Heine, A, Klebe, G. 登録日 2011-05-18 公開日 2012-06-06 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Transglutaminase 2 in complex with a novel inhibitor To be Published
1L9N	Three-dimensional structure of the human transglutaminase 3 enzyme: binding of calcium ions change structure for activation 分子名称: 2-O-octyl-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... 著者 Ahvazi, B. 登録日 2002-03-26 公開日 2002-05-29 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Three-dimensional structure of the human transglutaminase 3 enzyme: binding of calcium ions changes structure for activation. EMBO J., 21, 2002
1L9M	Three-dimensional structure of the human transglutaminase 3 enzyme: binding of calcium ions change structure for activation 分子名称: BROMIDE ION, CALCIUM ION, CHLORIDE ION, ... 著者 Ahvazi, B. 登録日 2002-03-26 公開日 2002-05-29 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Three-dimensional structure of the human transglutaminase 3 enzyme: binding of calcium ions changes structure for activation. EMBO J., 21, 2002
6I0I	Structure of the streptomyces subtilisin and TAMP inhibitor (SSTI) 分子名称: Transglutaminase-activating metalloprotease inhibitor 著者 Schmelz, S, Juettner, N.E, Fuchsbauer, H.L, Scrima, A. 登録日 2018-10-26 公開日 2019-09-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.448 Å) 主引用文献 The N-terminal peptide of the transglutaminase-activating metalloprotease inhibitor from Streptomyces mobaraensis accommodates both inhibition and glutamine cross-linking sites. Febs J., 287, 2020
1NUG	Role of Calcium Ions in the Activation and Activity of the Transglutaminase 3 Enzyme (2 calciums, 1 Mg, inactive form) 分子名称: CALCIUM ION, CHLORIDE ION, MAGNESIUM ION, ... 著者 Ahvazi, B. 登録日 2003-01-31 公開日 2003-04-22 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Roles of Calcium Ions in the Activation and Activity of the Transglutaminase 3 Enzyme J.Biol.Chem., 278, 2003
1NUD	Role of Calcium Ions in the Activation and Activity of the Transglutaminase 3 Enzyme (3 calciums, active form) 分子名称: BROMIDE ION, CALCIUM ION, CHLORIDE ION, ... 著者 Ahvazi, B. 登録日 2003-01-31 公開日 2003-04-22 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Roles of Calcium Ions in the Activation and Activity of the Transglutaminase 3 Enzyme J.Biol.Chem., 278, 2003
1NUF	Role of Calcium Ions in the Activation and Activity of the Transglutaminase 3 Enzyme 分子名称: BROMIDE ION, CALCIUM ION, CHLORIDE ION, ... 著者 Ahvazi, B. 登録日 2003-01-31 公開日 2003-04-22 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Roles of Calcium Ions in the Activation and Activity of the Transglutaminase 3 Enzyme J.Biol.Chem., 278, 2003
4ZD3	Structure of a transglutaminase 2-specific autoantibody Fab fragment 分子名称: 679-14-14E06 Fab fragment heavy chain, 679-14-14E06 Fab fragment light chain 著者 Chen, X, Dalhus, B, Hnida, K, Iversen, R, Sollid, L.M. 登録日 2015-04-16 公開日 2015-07-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural Basis for Antigen Recognition by Transglutaminase 2-specific Autoantibodies in Celiac Disease. J.Biol.Chem., 290, 2015
1G0D	CRYSTAL STRUCTURE OF RED SEA BREAM TRANSGLUTAMINASE 分子名称: PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE, SULFATE ION 著者 Noguchi, K, Ishikawa, K, Yokoyama, K, Ohtsuka, T, Nio, N, Suzuki, E. 登録日 2000-10-06 公開日 2001-05-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of red sea bream transglutaminase. J.Biol.Chem., 276, 2001
6GMG	Structure of a glutamine donor mimicking inhibitory peptide shaped by the catalytic cleft of microbial transglutaminase 分子名称: CITRATE ANION, DI(HYDROXYETHYL)ETHER, PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE, ... 著者 Schmelz, S, Juettner, N.E, Fuchsbauer, H.L, Scrima, A. 登録日 2018-05-25 公開日 2018-10-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure of a glutamine donor mimicking inhibitory peptide shaped by the catalytic cleft of microbial transglutaminase. FEBS J., 285, 2018
1KV3	HUMAN TISSUE TRANSGLUTAMINASE IN GDP BOUND FORM 分子名称: GUANOSINE-5'-DIPHOSPHATE, Protein-glutamine gamma-glutamyltransferase 著者 Liu, S, Cerione, R.A, Clardy, J. 登録日 2002-01-24 公開日 2002-03-13 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for the guanine nucleotide-binding activity of tissue transglutaminase and its regulation of transamidation activity. Proc.Natl.Acad.Sci.USA, 99, 2002
1GGT	THREE-DIMENSIONAL STRUCTURE OF A TRANSGLUTAMINASE: HUMAN BLOOD COAGULATION FACTOR XIII 分子名称: COAGULATION FACTOR XIII 著者 Yee, V.C, Pedersen, L.C, Trong, I.L, Bishop, P.D, Stenkamp, R.E, Teller, D.C. 登録日 1994-01-25 公開日 1995-07-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Three-dimensional structure of a transglutaminase: human blood coagulation factor XIII. Proc.Natl.Acad.Sci.USA, 91, 1994
5IT2	Structure of a transglutaminase 2-specific autoantibody 693-10-B06 Fab fragment 分子名称: heavy chain, light chain 著者 Chen, X, Dalhus, B, Hnida, K, Iversen, R, Sollid, L.M. 登録日 2016-03-16 公開日 2017-03-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 High abundance of plasma cells secreting transglutaminase 2-specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions Nat. Med., 18, 2012

 

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