PDB: 287 resultsInfo pagesStatus searchChemie searchBIRD

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5E6Q	Importin alpha binding to XRCC1 NLS peptide Descriptor: CHLORIDE ION, DNA repair protein XRCC1 NLS peptide, GLYCEROL, ... Authors: Pedersen, L.C, Kirby, T.W, Gassman, N.R, Smith, C.E, Gabel, S.A, Sobhany, M, Wilson, S.H, London, R.E. Deposit date: 2015-10-10 Release date: 2015-10-28 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.305 Å) Cite: Nuclear Localization of the DNA Repair Scaffold XRCC1: Uncovering the Functional Role of a Bipartite NLS. Sci Rep, 5, 2015
5EKF	Crystallization and X-ray Diffraction Data Collection of Importin-alpha from Mus musculus Complexed with a XPG NLS Peptide, fragment 1 Descriptor: DNA repair protein complementing XP-G cells, Importin subunit alpha-1 Authors: Barros, A.C, Takeda, A.A.S, Fontes, M.R.M. Deposit date: 2015-11-03 Release date: 2016-02-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural and Calorimetric Studies Demonstrate that Xeroderma Pigmentosum Type G (XPG) Can Be Imported to the Nucleus by a Classical Nuclear Import Pathway via a Monopartite NLS Sequence. J.Mol.Biol., 428, 2016
5EKG	Crystallization and X-ray Diffraction Data Collection of Importin-alpha from Mus musculus Complexed with a XPG NLS Peptide, fragment 2 Descriptor: Importin subunit alpha-1, XPG2 peptide Authors: Barros, A.C, Takeda, A.A.S, Fontes, M.R.M. Deposit date: 2015-11-03 Release date: 2016-02-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural and Calorimetric Studies Demonstrate that Xeroderma Pigmentosum Type G (XPG) Can Be Imported to the Nucleus by a Classical Nuclear Import Pathway via a Monopartite NLS Sequence. J.Mol.Biol., 428, 2016
7VPS	Crystal structure of the ARM domain of C. glabrata importin alpha Descriptor: Importin subunit alpha Authors: Tan, L, Im, Y.J. Deposit date: 2021-10-17 Release date: 2022-09-07 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Structural basis for activation of fungal sterol receptor Upc2 and azole resistance. Nat.Chem.Biol., 18, 2022
7VPT	Structure of the C. glabrata importin alpha ARM domain - Upc2 NLS fusion Descriptor: C. glabrata importin alpha ARM domain - Upc2 NLS fusion Authors: Tan, L, Im, Y.J. Deposit date: 2021-10-18 Release date: 2022-09-07 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural basis for activation of fungal sterol receptor Upc2 and azole resistance. Nat.Chem.Biol., 18, 2022
5FC8	Mouse importin alpha: Dengue 3 NS5 C-terminal NLS peptide complex Descriptor: Importin subunit alpha-1, Nonstructural protein 5 Authors: Smith, K.M, Forwood, J.K. Deposit date: 2015-12-15 Release date: 2016-05-18 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production. PLoS Pathog., 12, 2016
3LWW	Structure of an open and closed conformation of Human Importin Beta bound to the Snurportin1 IBB-domain trapped in the same crystallographic asymmetric unit Descriptor: Importin subunit beta-1, Snurportin-1 Authors: Bhardwaj, A, Cingolani, G. Deposit date: 2010-02-24 Release date: 2010-06-02 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Conformational selection in the recognition of the snurportin importin beta binding domain by importin beta. Biochemistry, 49, 2010
6IWA	Crystal structure of Importin-alpha and phosphoserine GM130 Descriptor: Importin subunit alpha-1, PHOSPHOSERINE GM130 Authors: Chang, C.-C, Chen, C.-J, Pien, Y.-C, Tsai, S.-Y, Hsia, K.-C. Deposit date: 2018-12-05 Release date: 2019-10-02 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Ran pathway-independent regulation of mitotic Golgi disassembly by Importin-alpha. Nat Commun, 10, 2019
1O6P	Importin Beta bound to a GLFG Nucleoporin peptide Descriptor: IMPORTIN BETA-1 SUBUNIT, SYNTHETIC GLFG PEPTIDE Authors: Bayliss, R, Stewart, M. Deposit date: 2002-10-10 Release date: 2003-04-24 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Glfg and Fxfg Nucleoporins Bind to Overlapping Sites on Importin-Beta J.Biol.Chem., 277, 2002
1O6O	Importin Beta aa1-442 bound to five FxFG repeats from yeast Nsp1p. Second crystal form Descriptor: IMPORTIN BETA-1 SUBUNIT, NUCLEOPORIN NSP1 Authors: Bayliss, R, Stewart, M. Deposit date: 2002-10-10 Release date: 2003-10-17 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Glfg and Fxfg Nucleoporins Bind to Overlapping Sites on Importin-Beta J.Biol.Chem., 277, 2002
6IU7	Crystal structure of importin-alpha1 bound to the 53BP1 nuclear localization signal (wild-type) Descriptor: Importin subunit alpha-1, Peptide from TP53-binding protein 1 Authors: Matsuura, Y. Deposit date: 2018-11-27 Release date: 2019-01-30 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural and biochemical characterization of the recognition of the 53BP1 nuclear localization signal by importin-alpha. Biochem. Biophys. Res. Commun., 510, 2019
6IUA	Crystal structure of importin-alpha1 bound to the 53BP1 nuclear localization signal (S1678D) Descriptor: Importin subunit alpha-1, Peptide from TP53-binding protein 1 Authors: Matsuura, Y. Deposit date: 2018-11-27 Release date: 2019-01-30 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural and biochemical characterization of the recognition of the 53BP1 nuclear localization signal by importin-alpha. Biochem. Biophys. Res. Commun., 510, 2019
6IW8	Crystal structure of Importin-alpha and wild-type GM130 Descriptor: Importin subunit alpha-1, Peptide from Golgin subfamily A member 2 Authors: Chang, C.-C, Chen, C.-J, Pien, Y.-C, Tsai, S.-Y, Hsia, K.-C. Deposit date: 2018-12-04 Release date: 2019-10-02 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Ran pathway-independent regulation of mitotic Golgi disassembly by Importin-alpha. Nat Commun, 10, 2019
3NMW	Crystal structure of armadillo repeats domain of APC Descriptor: APC variant protein, SULFATE ION Authors: Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G. Deposit date: 2010-06-22 Release date: 2011-07-06 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural basis for the recognition of Asef by adenomatous polyposis coli. Cell Res., 22, 2012
3NMX	Crystal structure of APC complexed with Asef Descriptor: APC variant protein, Rho guanine nucleotide exchange factor 4 Authors: Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G. Deposit date: 2010-06-22 Release date: 2011-07-06 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural basis for the recognition of Asef by adenomatous polyposis coli. Cell Res., 22, 2012
1PJN	Mouse Importin alpha-bipartite NLS N1N2 from Xenopus laevis phosphoprotein Complex Descriptor: Histone-binding protein N1/N2, Importin alpha-2 subunit Authors: Fontes, M.R.M, Teh, T, Jans, D, Brinkworth, R.I, Kobe, B. Deposit date: 2003-06-03 Release date: 2003-08-19 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha J.Biol.Chem., 278, 2003
1PJM	Mouse Importin alpha-bipartite NLS from human retinoblastoma protein Complex Descriptor: Importin alpha-2 subunit, Retinoblastoma-associated protein Authors: Fontes, M.R.M, Teh, T, Jans, D, Brinkworth, R.I, Kobe, B. Deposit date: 2003-06-03 Release date: 2003-08-19 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha J.Biol.Chem., 278, 2003
6K06	Crystal structure of Importin-alpha and phosphomimetic GM130 Descriptor: Importin subunit alpha-1, Peptide from Golgin subfamily A member 2 Authors: Chang, C.-C, Chen, C.-J, Pien, Y.-C, Tsai, S.-Y, Hsia, K.-C. Deposit date: 2019-05-05 Release date: 2019-10-02 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Ran pathway-independent regulation of mitotic Golgi disassembly by Importin-alpha. Nat Commun, 10, 2019
1Q1S	Mouse Importin alpha- phosphorylated SV40 CN peptide complex Descriptor: Importin alpha-2 subunit, Large T antigen Authors: Fontes, M.R.M, Teh, T, Toth, G, John, A, Pavo, I, Jans, D.A, Kobe, B. Deposit date: 2003-07-22 Release date: 2004-03-30 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha Biochem.J., 375, 2003
1Q1T	Mouse Importin alpha: non-phosphorylated SV40 CN peptide complex Descriptor: Importin alpha-2 subunit, Large T antigen Authors: Fontes, M.R.M, Teh, T, Toth, G, John, A, Pavo, I, Jans, D.A, Kobe, B. Deposit date: 2003-07-22 Release date: 2004-03-30 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha Biochem.J., 375, 2003
3OQS	Crystal structure of importin-alpha bound to a CLIC4 NLS peptide Descriptor: Importin subunit alpha-2, peptide of Chloride intracellular channel protein 4 Authors: Mynott, A.V, Brown, L.J, Harrop, S.J, Curmi, P.M.G. Deposit date: 2010-09-03 Release date: 2011-07-27 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of importin-alpha bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4 Febs J., 278, 2011
1QGR	STRUCTURE OF IMPORTIN BETA BOUND TO THE IBB DOMAIN OF IMPORTIN ALPHA (II CRYSTAL FORM, GROWN AT LOW PH) Descriptor: PROTEIN (IMPORTIN ALPHA-2 SUBUNIT), PROTEIN (IMPORTIN BETA SUBUNIT) Authors: Cingolani, G, Petosa, C, Weis, K, Muller, C.W. Deposit date: 1999-05-04 Release date: 1999-05-24 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure of importin-beta bound to the IBB domain of importin-alpha. Nature, 399, 1999
1QGK	STRUCTURE OF IMPORTIN BETA BOUND TO THE IBB DOMAIN OF IMPORTIN ALPHA Descriptor: PROTEIN (IMPORTIN ALPHA-2 SUBUNIT), PROTEIN (IMPORTIN BETA SUBUNIT) Authors: Cingolani, G, Petosa, C, Weis, K, Muller, C.W. Deposit date: 1999-04-29 Release date: 1999-05-24 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure of importin-beta bound to the IBB domain of importin-alpha. Nature, 399, 1999
1QZ7	Beta-catenin binding domain of Axin in complex with beta-catenin Descriptor: Axin, Beta-catenin Authors: Xing, Y, Clements, W.K, Kimelman, D, Xu, W. Deposit date: 2003-09-15 Release date: 2003-11-18 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of a beta-catenin/Axin complex suggests a mechanism for the {beta}-catenin destruction complex GENES DEV., 17, 2003
3Q5U	A minimal NLS from human scramblase 4 complexed with importin alpha Descriptor: Importin subunit alpha-2, Phospholipid scramblase 4 Authors: Bhardwaj, A, Cingolani, G. Deposit date: 2010-12-29 Release date: 2011-06-29 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: A Minimal Nuclear Localization Signal (NLS) in Human Phospholipid Scramblase 4 That Binds Only the Minor NLS-binding Site of Importin {alpha}1. J.Biol.Chem., 286, 2011

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