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2WA6
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BU of 2wa6 by Molmil
Structure of the W148R mutant of human filamin b actin binding domain at 1.95 Angstrom resolution
Descriptor: CARBONATE ION, FILAMIN-B
Authors:Sawyer, G.M, Clark, A.R, Robertson, S.P, Sutherland-Smith, A.J.
Deposit date:2009-02-03
Release date:2009-06-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Disease-Associated Substitutions in the Filamin B Actin Binding Domain Confer Enhanced Actin Binding Affinity in the Absence of Major Structural Disturbance: Insights from the Crystal Structures of Filamin B Actin Binding Domains.
J.Mol.Biol., 390, 2009
2WFN
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BU of 2wfn by Molmil
Filamin A actin binding domain
Descriptor: FILAMIN-A, SULFATE ION
Authors:Ruskamo, S, Ylanne, J.
Deposit date:2009-04-09
Release date:2009-10-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of the Human Filamin a Actin-Binding Domain
Acta Crystallogr.,Sect.D, 65, 2009
3REP
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BU of 3rep by Molmil
Crystal structure of the ILK/alpha-parvin core complex (MnATP)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Alpha-parvin, Integrin-linked kinase, ...
Authors:Fukuda, K, Qin, J.
Deposit date:2011-04-04
Release date:2011-04-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the ILK/alpha-parvin core complex (MnATP)
To be Published
6ICI
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BU of 6ici by Molmil
Crystal structure of human MICAL3
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, [F-actin]-monooxygenase MICAL3
Authors:Hwang, K.Y, Kim, J.S.
Deposit date:2018-09-06
Release date:2020-03-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and kinetic insights into flavin-containing monooxygenase and calponin-homology domains in human MICAL3.
Iucrj, 7, 2020
7ANK
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BU of 7ank by Molmil
Crystal structure of sarcomeric protein FATZ-1 (d91-FATZ-1 construct) in complex with half dimer of alpha-actinin-2
Descriptor: Alpha-actinin-2, Myozenin-1
Authors:Sponga, A, Arolas, J.L, Rodriguez Chamorro, A, Mlynek, G, Hollerl, E, Schreiner, C, Pedron, M, Kostan, J, Ribeiro, E.A, Djinovic-Carugo, K.
Deposit date:2020-10-12
Release date:2021-06-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.204 Å)
Cite:Order from disorder in the sarcomere: FATZ forms a fuzzy but tight complex and phase-separated condensates with alpha-actinin.
Sci Adv, 7, 2021
6ZSH
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BU of 6zsh by Molmil
The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members
Descriptor: EH domain-binding protein 1
Authors:Rai, A, Bleimling, N, Vetter, I.R, Goody, R.S.
Deposit date:2020-07-15
Release date:2020-09-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members.
Nat Commun, 11, 2020
8Y6K
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BU of 8y6k by Molmil
Cryo-EM structure of full-length MICAL1 in the autoinhibited state
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, ZINC ION, [F-actin]-monooxygenase MICAL1
Authors:Niu, F, Wei, Z.
Deposit date:2024-02-02
Release date:2024-08-28
Method:ELECTRON MICROSCOPY (3.94 Å)
Cite:Autoinhibition and relief mechanisms for MICAL monooxygenases in F-actin disassembly.
Nat Commun, 15, 2024
4B7L
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BU of 4b7l by Molmil
Crystal Structure of Human Filamin B Actin Binding Domain with 1st Filamin Repeat
Descriptor: FILAMIN-B
Authors:Sawyer, G.M, Sutherland-Smith, A.J.
Deposit date:2012-08-20
Release date:2012-10-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal Structure of the Filamin N-Terminal Region Reveals a Hinge between the Actin Binding and First Repeat Domains
J.Mol.Biol., 424, 2012
6MIB
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BU of 6mib by Molmil
Crystal structure of the ILK ATP-binding deficient mutant (L207W)/alpha-parvin core complex
Descriptor: Alpha-parvin, Integrin-linked protein kinase
Authors:Fukuda, K, Qin, J.
Deposit date:2018-09-19
Release date:2018-11-07
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Non-catalytic signaling by pseudokinase ILK for regulating cell adhesion.
Nat Commun, 9, 2018
4Q57
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BU of 4q57 by Molmil
Crystal structure of the plectin 1a actin-binding domain/N-terminal domain of calmodulin complex
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
Authors:Song, J.-G, Kostan, J, Grishkovskaya, I, Djinovic-Carugo, K.
Deposit date:2014-04-16
Release date:2014-07-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the plectin 1a actin-binding domain/N-terminal domain of calmodulin complex
To be Published
4TXI
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BU of 4txi by Molmil
Construct of MICAL-1 containing the monooxygenase and calponin homology domains
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Alqassim, S.S, Amzel, L.M, Bianchet, M.A.
Deposit date:2014-07-03
Release date:2016-01-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.309 Å)
Cite:Modulation of MICAL Monooxygenase Activity by its Calponin Homology Domain: Structural and Mechanistic Insights.
Sci Rep, 6, 2016
4TXK
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BU of 4txk by Molmil
Construct of MICAL-1 containing the monooxygenase and calponin homology domains
Descriptor: DI(HYDROXYETHYL)ETHER, FLAVIN-ADENINE DINUCLEOTIDE, Protein-methionine sulfoxide oxidase MICAL1
Authors:Alqassim, S.S, Amzel, L.M, Bianchet, M.A.
Deposit date:2014-07-03
Release date:2015-12-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.878 Å)
Cite:Structural insights into modulation of MICAL activity by its Calponin Homology (CH) domain
To Be Published
2K3S
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BU of 2k3s by Molmil
HADDOCK-derived structure of the CH-domain of the smoothelin-like 1 complexed with the C-domain of apocalmodulin
Descriptor: Calmodulin, Smoothelin-like protein 1
Authors:Ishida, H, Borman, M.A, Ostrander, J, Vogel, H.J, MacDonald, J.A.
Deposit date:2008-05-15
Release date:2008-05-27
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the calponin homology (CH) domain from the smoothelin-like 1 protein: a unique apocalmodulin-binding mode and the possible role of the C-terminal type-2 CH-domain in smooth muscle relaxation.
J.Biol.Chem., 283, 2008
3KMW
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BU of 3kmw by Molmil
Crystal structure of the ILK/alpha-parvin core complex (MgATP)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Alpha-parvin, Integrin-linked kinase, ...
Authors:Fukuda, K, Qin, J.
Deposit date:2009-11-11
Release date:2009-12-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:The pseudoactive site of ILK is essential for its binding to alpha-Parvin and localization to focal adhesions.
Mol.Cell, 36, 2009
3KMU
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BU of 3kmu by Molmil
Crystal structure of the ILK/alpha-parvin core complex (apo)
Descriptor: Alpha-parvin, Integrin-linked kinase
Authors:Fukuda, K, Qin, J.
Deposit date:2009-11-11
Release date:2009-12-29
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The pseudoactive site of ILK is essential for its binding to alpha-Parvin and localization to focal adhesions.
Mol.Cell, 36, 2009
4D1E
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BU of 4d1e by Molmil
THE CRYSTAL STRUCTURE OF HUMAN MUSCLE ALPHA-ACTININ-2
Descriptor: ALPHA-ACTININ-2
Authors:Pinotsis, N, Salmazo, A, Sjoeblom, B, Gkougkoulia, E, Djinovic-Carugo, K.
Deposit date:2014-05-01
Release date:2014-12-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The Structure and Regulation of Human Muscle Alpha-Actinin
Cell(Cambridge,Mass.), 159, 2014
1SJJ
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BU of 1sjj by Molmil
Cryo-EM Structure of Chicken Gizzard Smooth Muscle alpha-Actinin
Descriptor: actinin
Authors:Liu, J, Taylor, D.W, Taylor, K.A.
Deposit date:2004-03-03
Release date:2004-03-23
Last modified:2024-02-14
Method:ELECTRON CRYSTALLOGRAPHY (20 Å)
Cite:A 3-D Reconstruction of Smooth Muscle alpha-Actinin by CryoEm Reveals Two Different Conformations at the Actin-binding Region.
J.Mol.Biol., 338, 2004
2R8U
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BU of 2r8u by Molmil
Structure of fragment of human end-binding protein 1 (EB1) containing the N-terminal domain at 1.35 A resolution
Descriptor: MOLYBDATE ION, Microtubule-associated protein RP/EB family member 1
Authors:Huang, X, Lovelace, L.L, Smith, D, Lebioda, L.
Deposit date:2007-09-11
Release date:2008-09-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure of fragment of human end-binding protein 1 (EB1) containing the N-terminal domain at 1.35 A resolution
To be Published
7SJ9
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BU of 7sj9 by Molmil
13pf E254A microtubule from recombinant human tubulin decorated with EB3
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Microtubule-associated protein RP/EB family member 3, ...
Authors:LaFrance, B.J, Greber, B.J, Zhang, R, McCollum, C, Nogales, E.
Deposit date:2021-10-16
Release date:2022-01-19
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural transitions in the GTP cap visualized by cryo-electron microscopy of catalytically inactive microtubules.
Proc.Natl.Acad.Sci.USA, 119, 2022
6D8C
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BU of 6d8c by Molmil
Cryo-EM structure of FLNaABD E254K bound to phalloidin-stabilized F-actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Iwamoto, D.V, Huehn, A.R, Simon, B, Huet-Calderwood, C, Baldassarre, M, Sindelar, C.V, Calderwood, D.A.
Deposit date:2018-04-26
Release date:2018-09-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Structural basis of the filamin A actin-binding domain interaction with F-actin.
Nat. Struct. Mol. Biol., 25, 2018
7R94
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BU of 7r94 by Molmil
T-Plastin-F-actin complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Mei, L, Alushin, G.M.
Deposit date:2021-06-28
Release date:2022-07-06
Last modified:2022-09-21
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural mechanism for bidirectional actin cross-linking by T-plastin.
Proc.Natl.Acad.Sci.USA, 119, 2022
6ANU
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BU of 6anu by Molmil
Cryo-EM structure of F-actin complexed with the beta-III-spectrin actin-binding domain
Descriptor: Actin, cytoplasmic 1, Spectrin beta chain, ...
Authors:Wang, F, Orlova, A, Avery, A.W, Hays, T.S, Egelman, E.H.
Deposit date:2017-08-14
Release date:2017-11-22
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Structural basis for high-affinity actin binding revealed by a beta-III-spectrin SCA5 missense mutation.
Nat Commun, 8, 2017
7N6G
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BU of 7n6g by Molmil
C1 of central pair
Descriptor: CPC1, Calmodulin, DPY30, ...
Authors:Han, L, Zhang, K.
Deposit date:2021-06-08
Release date:2022-05-18
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of an active central apparatus.
Nat.Struct.Mol.Biol., 29, 2022
8IAH
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BU of 8iah by Molmil
Structure of mammalian spectrin-actin junctional complex of membrane skeleton, State I, Global map
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ...
Authors:Li, N, Chen, S, Gao, N.
Deposit date:2023-02-08
Release date:2023-05-03
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis of membrane skeleton organization in red blood cells.
Cell, 186, 2023
8IAI
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BU of 8iai by Molmil
Structure of mammalian spectrin-actin junctional complex of membrane skeleton, State II, Global map
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ...
Authors:Li, N, Chen, S, Gao, N.
Deposit date:2023-02-08
Release date:2023-05-03
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of membrane skeleton organization in red blood cells.
Cell, 186, 2023

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