4B7L

Crystal Structure of Human Filamin B Actin Binding Domain with 1st Filamin Repeat

Summary for 4B7L

Entry DOI	10.2210/pdb4b7l/pdb
Related	2DI8 2DI9 2DIA 2DIB 2DIC 2DJ4 2WA5 2WA6 2WA7
Descriptor	FILAMIN-B (2 entities in total)
Functional Keywords	structural protein, fr 1 filamin hinge abd-1
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Isoform 1: Cytoplasm, cell cortex. Isoform 2: Cytoplasm, cytoskeleton. Isoform 3: Cytoplasm, cytoskeleton. Isoform 6: Cytoplasm, cytoskeleton: O75369
Total number of polymer chains	2
Total formula weight	78571.66
Authors	Sawyer, G.M.,Sutherland-Smith, A.J. (deposition date: 2012-08-20, release date: 2012-10-10, Last modification date: 2023-12-20)
Primary citation	Sawyer, G.M.,Sutherland-Smith, A.J. Crystal Structure of the Filamin N-Terminal Region Reveals a Hinge between the Actin Binding and First Repeat Domains J.Mol.Biol., 424:240-, 2012 Cited by PubMed: 23036857 DOI: 10.1016/J.JMB.2012.09.016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation