4B7L

Crystal Structure of Human Filamin B Actin Binding Domain with 1st Filamin Repeat

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0030036	biological_process	actin cytoskeleton organization
A	0051015	molecular_function	actin filament binding
B	0030036	biological_process	actin cytoskeleton organization
B	0051015	molecular_function	actin filament binding

Functional Information from PROSITE/UniProt

site_id	PS00019
Number of Residues	10
Details	ACTININ_1 Actinin-type actin-binding domain signature 1. QQnTFTRWCN

Chain	Residue	Details
A	GLN18-ASN27

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site_id	PS00020
Number of Residues	25
Details	ACTININ_2 Actinin-type actin-binding domain signature 2. LvSIDSkAIvDgnlkLiLGLVWtLI

Chain	Residue	Details
A	LEU94-ILE118

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	212
Details	Domain: {"description":"Calponin-homology (CH) 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00044","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	206
Details	Domain: {"description":"Calponin-homology (CH) 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00044","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	196
Details	Repeat: {"description":"Filamin 1"}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	46
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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