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8TE1
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BU of 8te1 by Molmil
Crystal structure of the methyltransferase domain of R882H/R676K DNMT3A homotetramer
Descriptor: DNA (cytosine-5)-methyltransferase 3A, GLYCEROL, L(+)-TARTARIC ACID, ...
Authors:Lu, J.W, Song, J.K.
Deposit date:2023-07-05
Release date:2024-03-13
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Crystal structure of the methyltransferase domain of R882H/R676K DNMT3A homotetramer
To Be Published
6U8X
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BU of 6u8x by Molmil
Crystal structure of DNMT3B-DNMT3L in complex with CpApG DNA
Descriptor: CpApG DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ...
Authors:Gao, L, Song, J.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.95063877 Å)
Cite:Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms.
Nat Commun, 11, 2020
8TE4
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BU of 8te4 by Molmil
Crystal structure of the methyltransferase domain of R882H/N879A DNMT3A homotetramer
Descriptor: DNA (cytosine-5)-methyltransferase 3A, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Lu, J.W, Song, J.K.
Deposit date:2023-07-05
Release date:2024-03-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structure of the methyltransferase domain of R882H/N879A DNMT3A homotetramer
To Be Published
6U91
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BU of 6u91 by Molmil
Crystal structure of DNMT3B(Q772R)-DNMT3L in complex with CpGpT DNA
Descriptor: CpGpT DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ...
Authors:Gao, L, Song, J.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.99998879 Å)
Cite:Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms
To Be Published
8TCI
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BU of 8tci by Molmil
Crystal structure of DNMT3C-DNMT3L in complex with CGG DNA
Descriptor: (5'-D(P*CP*AP*TP*G)-R(P*(PYO))-D(P*GP*GP*TP*CP*TP*AP*AP*TP*TP*AP*GP*AP*CP*CP*GP*CP*AP*TP*G)-3'), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3C, ...
Authors:Khudaverdyan, N, Song, J.
Deposit date:2023-07-01
Release date:2024-08-14
Last modified:2024-09-11
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:The structure of DNA methyltransferase DNMT3C reveals an activity-tuning mechanism for DNA methylation.
J.Biol.Chem., 300, 2024
6U8P
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BU of 6u8p by Molmil
Crystal structure of DNMT3B-DNMT3L in complex with CpGpA DNA
Descriptor: CpGpA DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ...
Authors:Gao, L, Song, J.
Deposit date:2019-09-05
Release date:2020-06-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms.
Nat Commun, 11, 2020
6U90
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BU of 6u90 by Molmil
Crystal structure of DNMT3B(N779A)-DNMT3L in complex with CpGpT DNA
Descriptor: CpGpT DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ...
Authors:Gao, L, Song, J.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.00081754 Å)
Cite:Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms
To Be Published
6U8V
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BU of 6u8v by Molmil
Crystal structure of DNMT3B-DNMT3L in complex with CpGpT DNA
Descriptor: CpGpT DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ...
Authors:Gao, L, Zhang, Z.M, Song, J.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms.
Nat Commun, 11, 2020
6U8W
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BU of 6u8w by Molmil
Crystal structure of DNMT3B(K777A)-DNMT3L in complex with CpGpT DNA
Descriptor: CpGpT DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ...
Authors:Gao, L, Zhang, Z.M, Song, J.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.94891548 Å)
Cite:Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms.
Nat Commun, 11, 2020
6KDL
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BU of 6kdl by Molmil
Crystal structure of human DNMT3B-DNMT3L complex (I)
Descriptor: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S.
Deposit date:2019-07-02
Release date:2020-02-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.274 Å)
Cite:Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B.
Nucleic Acids Res., 48, 2020
6KDP
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BU of 6kdp by Molmil
Crystal structure of human DNMT3B-DNMT3L complex (II)
Descriptor: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, FORMIC ACID, ...
Authors:Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S.
Deposit date:2019-07-02
Release date:2020-02-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B.
Nucleic Acids Res., 48, 2020
6KDB
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BU of 6kdb by Molmil
Crystal structure of human DNMT3B-DNMT3L in complex with DNA containing CpGpT site
Descriptor: DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ...
Authors:Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S.
Deposit date:2019-07-01
Release date:2020-02-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.862 Å)
Cite:Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B.
Nucleic Acids Res., 48, 2020
6KDT
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BU of 6kdt by Molmil
Crystal structure of human DNMT3B (Q772R)-DNMT3L complex
Descriptor: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, FORMIC ACID, ...
Authors:Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S.
Deposit date:2019-07-02
Release date:2020-02-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B.
Nucleic Acids Res., 48, 2020
6KDA
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BU of 6kda by Molmil
Crystal structure of human DNMT3B-DNMT3L in complex with DNA containing CpGpG site
Descriptor: DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ...
Authors:Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S.
Deposit date:2019-07-01
Release date:2020-02-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.909 Å)
Cite:Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B.
Nucleic Acids Res., 48, 2020
6MHT
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BU of 6mht by Molmil
TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH ADOHCY AND DNA CONTAINING 4'-THIO-2'DEOXYCYTIDINE AT THE TARGET
Descriptor: CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, DNA (5'-D(P*CP*CP*AP*TP*GP*(5CM)P*GP*CP*TP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*AP*GP*(4SC)P*GP*CP*AP*TP*GP*G)-3'), ...
Authors:Cheng, X.
Deposit date:1998-08-05
Release date:1998-08-12
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:DNA containing 4'-thio-2'-deoxycytidine inhibits methylation by HhaI methyltransferase.
Nucleic Acids Res., 25, 1997
6W89
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BU of 6w89 by Molmil
Structure of DNMT3A (R882H) in complex with CGA DNA
Descriptor: CGA DNA (25-MER), CITRIC ACID, DNA (cytosine-5)-methyltransferase 3-like, ...
Authors:Anteneh, H, Song, J.
Deposit date:2020-03-20
Release date:2020-04-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.499 Å)
Cite:Structural basis for impairment of DNA methylation by the DNMT3A R882H mutation.
Nat Commun, 11, 2020
6W8J
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BU of 6w8j by Molmil
Structure of DNMT3A (R882H) in complex with CAG DNA
Descriptor: CAG DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, ...
Authors:Anteneh, H, Song, J.
Deposit date:2020-03-20
Release date:2020-04-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.445 Å)
Cite:Structural basis for impairment of DNA methylation by the DNMT3A R882H mutation.
Nat Commun, 11, 2020
6W8D
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BU of 6w8d by Molmil
Structure of DNMT3A (R882H) in complex with CGT DNA
Descriptor: CGT DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, ...
Authors:Anteneh, H, Song, J.
Deposit date:2020-03-20
Release date:2020-04-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.598 Å)
Cite:Structural basis for impairment of DNA methylation by the DNMT3A R882H mutation.
Nat Commun, 11, 2020
7L4C
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BU of 7l4c by Molmil
Crystal structure of the DRM2-CTT DNA complex
Descriptor: DNA (5'-D(*AP*TP*TP*AP*TP*TP*AP*AP*TP*(C49)P*TP*TP*AP*AP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*TP*TP*AP*AP*GP*AP*TP*TP*AP*AP*TP*AP*AP*T)-3'), DNA (cytosine-5)-methyltransferase DRM2, ...
Authors:Fang, J, Song, J.
Deposit date:2020-12-18
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Substrate deformation regulates DRM2-mediated DNA methylation in plants.
Sci Adv, 7, 2021
7L4H
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BU of 7l4h by Molmil
Crystal structure of the DRM2-CTG DNA complex
Descriptor: DNA (5'-D(*AP*TP*TP*CP*CP*TP*AP*AP*TP*(C49)P*TP*GP*AP*AP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*TP*TP*CP*AP*GP*AP*TP*TP*AP*GP*GP*AP*AP*T)-3'), DNA (cytosine-5)-methyltransferase DRM2, ...
Authors:Fang, J, Song, J.
Deposit date:2020-12-19
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Substrate deformation regulates DRM2-mediated DNA methylation in plants.
Sci Adv, 7, 2021
7L4K
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BU of 7l4k by Molmil
Crystal structure of the DRM2-CCG DNA complex
Descriptor: DNA (5'-D(*AP*TP*TP*CP*CP*TP*AP*AP*TP*(C49)P*CP*GP*AP*AP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*TP*TP*CP*GP*GP*AP*TP*TP*AP*GP*GP*AP*AP*T)-3'), DNA (cytosine-5)-methyltransferase DRM2, ...
Authors:Fang, J, Song, J.
Deposit date:2020-12-19
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Substrate deformation regulates DRM2-mediated DNA methylation in plants.
Sci Adv, 7, 2021
7L4N
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BU of 7l4n by Molmil
Crystal structure of the DRM2 (C397R)-CCG DNA complex
Descriptor: DNA (5'-D(*AP*TP*TP*CP*CP*TP*AP*AP*TP*(C49)P*CP*GP*AP*AP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*TP*TP*CP*GP*GP*AP*TP*TP*AP*GP*GP*AP*AP*T)-3'), DNA (cytosine-5)-methyltransferase DRM2, ...
Authors:Fang, J, Song, J.
Deposit date:2020-12-19
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.247 Å)
Cite:Substrate deformation regulates DRM2-mediated DNA methylation in plants.
Sci Adv, 7, 2021
7L4M
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BU of 7l4m by Molmil
Crystal structure of the DRM2-CCT DNA complex
Descriptor: DNA (5'-D(*TP*AP*AP*AP*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*AP*AP*T)-3'), DNA (5'-D(P*AP*TP*TP*CP*CP*TP*CP*CP*TP*(C49)P*CP*TP*CP*CP*TP*TP*TP*A)-3'), DNA (cytosine-5)-methyltransferase DRM2, ...
Authors:Fang, J, Song, J.
Deposit date:2020-12-19
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.805 Å)
Cite:Substrate deformation regulates DRM2-mediated DNA methylation in plants.
Sci Adv, 7, 2021
7L4F
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BU of 7l4f by Molmil
Crystal structure of the DRM2-CAT DNA complex
Descriptor: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, DNA (5'-D(*AP*TP*TP*CP*CP*TP*CP*CP*TP*(C49)P*AP*TP*CP*CP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*GP*GP*AP*TP*GP*AP*GP*GP*AP*GP*GP*AP*AP*T)-3'), ...
Authors:Fang, J, Song, J.
Deposit date:2020-12-19
Release date:2021-08-04
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Substrate deformation regulates DRM2-mediated DNA methylation in plants.
Sci Adv, 7, 2021
2ZCJ
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BU of 2zcj by Molmil
Ternary structure of the Glu119Gln M.HhaI, C5-Cytosine DNA methyltransferase, with unmodified DNA and AdoHcy
Descriptor: DNA (5'-D(*DGP*DAP*DTP*DAP*DGP*DCP*DGP*DCP*DTP*DAP*DTP*DC)-3'), DNA (5'-D(*DTP*DGP*DAP*DTP*DAP*DGP*DCP*DGP*DCP*DTP*DAP*DTP*DC)-3'), Modification methylase HhaI, ...
Authors:Shieh, F.K, Reich, N.O.
Deposit date:2007-11-09
Release date:2007-12-04
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:AdoMet-dependent Methyl-transfer: Glu(119) Is Essential for DNA C5-Cytosine Methyltransferase M.HhaI
J.Mol.Biol., 373, 2007

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PDB entries from 2024-09-18

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