8TE1

Crystal structure of the methyltransferase domain of R882H/R676K DNMT3A homotetramer

Summary for 8TE1

Entry DOI	10.2210/pdb8te1/pdb
Descriptor	DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE, GLYCEROL, ... (5 entities in total)
Functional Keywords	dna metyltransferase, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	8
Total formula weight	265202.98
Authors	Lu, J.W.,Song, J.K. (deposition date: 2023-07-05, release date: 2024-03-13)
Primary citation	Lu, J.W.,Song, J.K. Crystal structure of the methyltransferase domain of R882H/R676K DNMT3A homotetramer To Be Published,
Experimental method	X-RAY DIFFRACTION (2.48 Å)

Structure validation