2BJC
| NMR structure of a protein-DNA complex of an altered specificity mutant of the lac repressor headpiece that mimics the gal repressor | Descriptor: | 5'-D(*GP*AP*AP*TP*TP*GP*TP*AP*AP*GP *CP*GP*CP*TP*TP*AP*CP*AP*AP*TP*TP*C)-3', LACTOSE OPERON REPRESSOR | Authors: | Salinas, R.K, Folkers, G.E, Bonvin, A.M.J.J, Das, D, Boelens, R, Kaptein, R. | Deposit date: | 2005-02-01 | Release date: | 2005-10-18 | Last modified: | 2020-01-15 | Method: | SOLUTION NMR | Cite: | Altered Specificity in DNA Binding by the Lac Repressor: A Mutant Lac Headpiece that Mimics the Gal Repressor Chembiochem, 6, 2005
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1CJG
| NMR STRUCTURE OF LAC REPRESSOR HP62-DNA COMPLEX | Descriptor: | DNA (5'-D(*GP*AP*AP*TP*TP*GP*TP*GP*AP*GP*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*TP*C)-3'), PROTEIN (LAC REPRESSOR) | Authors: | Spronk, C.A.E.M, Bonvin, A.M.J.J, Radha, P.K, Melacini, G, Boelens, R, Kaptein, R. | Deposit date: | 1999-04-14 | Release date: | 2000-01-01 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | The solution structure of Lac repressor headpiece 62 complexed to a symmetrical lac operator. Structure Fold.Des., 7, 1999
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2KEJ
| Solution structure of a dimer of LAC repressor DNA-binding domain complexed to its natural operator O2 | Descriptor: | DNA (5'-D(*GP*AP*AP*AP*TP*GP*TP*GP*AP*GP*CP*GP*AP*GP*TP*AP*AP*CP*AP*AP*CP*CP*G)-3'), DNA (5'-D(P*CP*GP*GP*TP*TP*GP*TP*TP*AP*CP*TP*CP*GP*CP*TP*CP*AP*CP*AP*TP*TP*TP*C)-3'), Lactose operon repressor | Authors: | Romanuka, J, Folkers, G, Biris, N, Tishchenko, E, Wienk, H, Kaptein, R, Boelens, R. | Deposit date: | 2009-01-30 | Release date: | 2009-05-19 | Last modified: | 2021-10-20 | Method: | SOLUTION NMR | Cite: | Specificity and affinity of Lac repressor for the auxiliary operators O2 and O3 are explained by the structures of their protein-DNA complexes. J.Mol.Biol., 390, 2009
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2LCV
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1UXD
| Fructose repressor DNA-binding domain, NMR, 34 structures | Descriptor: | FRUCTOSE REPRESSOR | Authors: | Penin, F, Geourjon, C, Montserret, R, Bockmann, A, Lesage, A, Yang, Y, Bonod-Bidaud, C, Cortay, J.C, Negre, D, Cozzone, A.J, Deleage, G. | Deposit date: | 1996-12-26 | Release date: | 1997-04-01 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Three-dimensional structure of the DNA-binding domain of the fructose repressor from Escherichia coli by 1H and 15N NMR. J.Mol.Biol., 270, 1997
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1UXC
| FRUCTOSE REPRESSOR DNA-BINDING DOMAIN, NMR, MINIMIZED STRUCTURE | Descriptor: | FRUCTOSE REPRESSOR | Authors: | Penin, F, Geourjon, C, Montserret, R, Bockmann, A, Lesage, A, Yang, Y, Bonod-Bidaud, C, Cortay, J.C, Negre, D, Cozzone, A.J, Deleage, G. | Deposit date: | 1996-12-26 | Release date: | 1997-04-21 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Three-dimensional structure of the DNA-binding domain of the fructose repressor from Escherichia coli by 1H and 15N NMR. J.Mol.Biol., 270, 1997
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2KEI
| Refined Solution Structure of a Dimer of LAC repressor DNA-Binding domain complexed to its natural operator O1 | Descriptor: | DNA (5'-D(*GP*AP*AP*TP*TP*GP*TP*GP*AP*GP*CP*GP*GP*AP*TP*AP*AP*CP*AP*AP*TP*TP*T)-3'), DNA (5'-D(P*AP*AP*AP*TP*TP*GP*TP*TP*AP*TP*CP*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*TP*C)-3'), Lactose operon repressor | Authors: | Romanuka, J, Folkers, G, Biris, N, Tishchenko, E, Wienk, H, Kaptein, R, Boelens, R. | Deposit date: | 2009-01-30 | Release date: | 2009-05-19 | Last modified: | 2021-10-20 | Method: | SOLUTION NMR | Cite: | Specificity and affinity of Lac repressor for the auxiliary operators O2 and O3 are explained by the structures of their protein-DNA complexes. J.Mol.Biol., 390, 2009
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2KEK
| Solution structure of a dimer of LAC repressor DNA-binding domain complexed to its natural operator O3 | Descriptor: | DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*GP*AP*GP*CP*GP*CP*AP*AP*CP*GP*CP*AP*AP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*TP*TP*GP*CP*GP*TP*TP*GP*CP*GP*CP*TP*CP*AP*CP*TP*GP*CP*CP*G)-3'), Lactose operon repressor | Authors: | Romanuka, J, Folkers, G, Biris, N, Tishchenko, E, Wienk, H, Kaptein, R, Boelens, R. | Deposit date: | 2009-01-30 | Release date: | 2009-05-19 | Last modified: | 2021-10-20 | Method: | SOLUTION NMR | Cite: | Specificity and affinity of Lac repressor for the auxiliary operators O2 and O3 are explained by the structures of their protein-DNA complexes. J.Mol.Biol., 390, 2009
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1OSL
| Solution structure of a dimeric lactose DNA-binding domain complexed to a nonspecific DNA sequence | Descriptor: | 5'-D(*CP*GP*AP*TP*AP*AP*GP*AP*TP*AP*TP*CP*TP*TP*AP*TP*CP*G)-3', Lactose operon repressor | Authors: | Kalodimos, C.G, Bonvin, A.M.J.J, Boelens, R, Kaptein, R. | Deposit date: | 2003-03-20 | Release date: | 2004-05-04 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | Structure and flexibility adaptation in nonspecific and specific protein-DNA complexes. Science, 305, 2004
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1PRU
| PURINE REPRESSOR DNA-BINDING DOMAIN DNA BINDING | Descriptor: | PURINE REPRESSOR | Authors: | Nagadoi, A, Morikawa, S, Nakamura, H, Enari, M, Kobayashi, K, Yamamoto, H, Sampei, G, Mizobuchi, K, Schumacher, M.A, Brennan, R.G, Nishimura, Y. | Deposit date: | 1995-05-08 | Release date: | 1996-03-08 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural comparison of the free and DNA-bound forms of the purine repressor DNA-binding domain. Structure, 3, 1995
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1PRV
| PURINE REPRESSOR DNA-BINDING DOMAIN DNA BINDING | Descriptor: | PURINE REPRESSOR | Authors: | Nagadoi, A, Morikawa, S, Nakamura, H, Enari, M, Kobayashi, K, Yamamoto, H, Sampei, G, Mizobuchi, K, Schumacher, M.A, Brennan, R.G, Nishimura, Y. | Deposit date: | 1995-05-08 | Release date: | 1996-03-08 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural comparison of the free and DNA-bound forms of the purine repressor DNA-binding domain. Structure, 3, 1995
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1L1M
| SOLUTION STRUCTURE OF A DIMER OF LAC REPRESSOR DNA-BINDING DOMAIN COMPLEXED TO ITS NATURAL OPERATOR O1 | Descriptor: | 5'-D(*AP*AP*AP*TP*TP*GP*TP*TP*AP*TP*CP*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*TP*C)-3', 5'-D(*GP*AP*AP*TP*TP*GP*TP*GP*AP*GP*CP*GP*GP*AP*TP*AP*AP*CP*AP*AP*TP*TP*T)-3', Lactose operon repressor | Authors: | Kalodimos, C.G, Bonvin, A.M.J.J, Salinas, R.K, Wechselberger, R, Boelens, R, Kaptein, R. | Deposit date: | 2002-02-19 | Release date: | 2002-06-26 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | Plasticity in protein-DNA recognition: lac repressor interacts with its natural operator 01 through alternative conformations of its DNA-binding domain. EMBO J., 21, 2002
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1LQC
| LAC REPRESSOR HEADPIECE (RESIDUES 1-56), NMR, 32 STRUCTURES | Descriptor: | LAC REPRESSOR | Authors: | Slijper, M, Bonvin, A.M.J.J, Boelens, R, Kaptein, R. | Deposit date: | 1996-08-13 | Release date: | 1997-02-12 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Refined structure of lac repressor headpiece (1-56) determined by relaxation matrix calculations from 2D and 3D NOE data: change of tertiary structure upon binding to the lac operator. J.Mol.Biol., 259, 1996
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1LCC
| STRUCTURE OF THE COMPLEX OF LAC REPRESSOR HEADPIECE AND AN 11 BASE-PAIR HALF-OPERATOR DETERMINED BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND RESTRAINED MOLECULAR DYNAMICS | Descriptor: | DNA (5'-D(*AP*AP*TP*TP*GP*TP*GP*AP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*T)-3'), Lac Repressor, ... | Authors: | Chuprina, V.P, Rullmann, J.A.C, Lamerichs, R.M.J.N, Van Boom, J.H, Boelens, R, Kaptein, R. | Deposit date: | 1993-03-25 | Release date: | 1994-01-31 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of the complex of lac repressor headpiece and an 11 base-pair half-operator determined by nuclear magnetic resonance spectroscopy and restrained molecular dynamics. J.Mol.Biol., 234, 1993
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1LCD
| STRUCTURE OF THE COMPLEX OF LAC REPRESSOR HEADPIECE AND AN 11 BASE-PAIR HALF-OPERATOR DETERMINED BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND RESTRAINED MOLECULAR DYNAMICS | Descriptor: | DNA (5'-D(*AP*AP*TP*TP*GP*TP*GP*AP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*T)-3'), Lac Repressor, ... | Authors: | Chuprina, V.P, Rullmann, J.A.C, Lamerichs, R.M.J.N, Van Boom, J.H, Boelens, R, Kaptein, R. | Deposit date: | 1993-03-25 | Release date: | 1994-01-31 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of the complex of lac repressor headpiece and an 11 base-pair half-operator determined by nuclear magnetic resonance spectroscopy and restrained molecular dynamics. J.Mol.Biol., 234, 1993
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1ZVV
| Crystal structure of a ccpa-crh-dna complex | Descriptor: | DNA recognition strand CRE, Glucose-resistance amylase regulator, HPr-like protein crh, ... | Authors: | Schumacher, M.A, Brennan, R.G, Hillen, W, Seidel, G. | Deposit date: | 2005-06-02 | Release date: | 2006-02-07 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | Phosphoprotein Crh-Ser46-P displays altered binding to CcpA to effect carbon catabolite regulation. J.Biol.Chem., 281, 2006
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3KJX
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5UFH
| The crystal structure of a LacI-type transcription regulator from Bifidobacterium animalis subsp. lactis DSM 10140 | Descriptor: | GLYCEROL, LacI-type transcriptional regulator, NITRATE ION | Authors: | Tan, K, Li, H, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2017-01-04 | Release date: | 2017-01-18 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | The crystal structure of a LacI-type transcription regulator from Bifidobacterium animalis subsp. lactis DSM 10140 To Be Published
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5YSZ
| transcriptional regulator CelR-cellobiose complex | Descriptor: | GLYCEROL, Transcriptional regulator, LacI family, ... | Authors: | Fu, Y, Yeom, S.Y, Lee, D.H, Lee, S.G. | Deposit date: | 2017-11-16 | Release date: | 2018-08-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.631 Å) | Cite: | Structural and functional analyses of the cellulase transcription regulator CelR FEBS Lett., 592, 2018
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7FF4
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6NDI
| Crystal Structure of the Sugar Binding Domain of LacI Family Protein from Klebsiella pneumoniae | Descriptor: | Transcriptional regulator | Authors: | Minasov, G, Shuvalova, L, Wawrzak, Z, Kiryukhina, O, Dubrovska, I, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2018-12-13 | Release date: | 2018-12-26 | Last modified: | 2023-06-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A Structural Systems Biology Approach to High-Risk CG23 Klebsiella pneumoniae. Microbiol Resour Announc, 12, 2023
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7X7H
| Crystal structure of Fructose regulator/Histidine phosphocarrier protein complex from Vibrio cholerae | Descriptor: | CALCIUM ION, Catabolite repressor/activator, HPr family phosphocarrier protein | Authors: | Kim, M.-K, Zhang, J, Yoon, C.-K, Seok, Y.-J. | Deposit date: | 2022-03-09 | Release date: | 2023-03-15 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | HPr prevents FruR-mediated facilitation of RNA polymerase binding to the fru promoter in Vibrio cholerae. Nucleic Acids Res., 51, 2023
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3BIL
| Crystal structure of a probable LacI family transcriptional regulator from Corynebacterium glutamicum | Descriptor: | Probable LacI-family transcriptional regulator | Authors: | Bonanno, J.B, Freeman, J, Bain, K.T, Mendoza, M, Ozyurt, S, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-11-30 | Release date: | 2007-12-11 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of a probable LacI family transcriptional regulator from Corynebacterium glutamicum. To be Published
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8JFV
| Crystal structure of Catabolite repressor acivator from E. coli in complex with sulisobenzone | Descriptor: | 1,2-ETHANEDIOL, 2-methoxy-4-oxidanyl-5-(phenylcarbonyl)benzenesulfonic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Neetu, N, Sharma, M, Mahto, J.K, Kumar, P. | Deposit date: | 2023-05-19 | Release date: | 2024-04-24 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Sulisobenzone is a potent inhibitor of the global transcription factor Cra. J.Struct.Biol., 215, 2023
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8JFF
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