PDB: 293 件ウェブページステータス検索Chemie searchBIRD

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6PFJ	Structure of S. venezuelae RsiG-WhiG-(ci-di-GMP) complex, P64 crystal form 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), AmfC protein, RNA polymerase sigma factor 著者 Schumacher, M.A. 登録日 2019-06-21 公開日 2019-11-13 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 c-di-GMP Arms an Anti-sigma to Control Progression of Multicellular Differentiation in Streptomyces. Mol.Cell, 77, 2020
6PFV	Structure of S. venezuelae RisG-WhiG-c-di-GMP complex: orthorhombic crystal form 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), AmfC protein, RNA polymerase sigma factor 著者 Schumacher, M.A. 登録日 2019-06-22 公開日 2019-11-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 c-di-GMP Arms an Anti-sigma to Control Progression of Multicellular Differentiation in Streptomyces. Mol.Cell, 77, 2020
3WOD	RNA polymerase-gp39 complex 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Tagami, S, Sekine, S, Minakhin, L, Esyunina, D, Akasaka, R, Shirouzu, M, Kulbachinskiy, A, Severinov, K, Yokoyama, S. 登録日 2013-12-26 公開日 2014-03-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structural basis for promoter specificity switching of RNA polymerase by a phage factor. Genes Dev., 28, 2014
4Q4Z	Thermus thermophilus RNA polymerase de novo transcription initiation complex 分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, ADENOSINE-5'-TRIPHOSPHATE, DNA (25-MER), ... 著者 Murakami, K.S. 登録日 2014-04-15 公開日 2014-07-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis of transcription initiation by bacterial RNA polymerase holoenzyme. J.Biol.Chem., 289, 2014
7P5X	Mycobacterial RNAP with transcriptional activator PafBC 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Mueller, A.U, Kummer, E, Schilling, C.M, Ban, N, Weber-Ban, E. 登録日 2021-07-15 公開日 2021-12-22 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Transcriptional control of mycobacterial DNA damage response by sigma adaptation. Sci Adv, 7, 2021
8FTD	Structure of Escherichia coli CedA in complex with transcription initiation complex 分子名称: CHAPSO, Cell division activator CedA, DNA-directed RNA polymerase subunit alpha, ... 著者 Liu, M, Vassyliev, N, Nudler, E. 登録日 2023-01-11 公開日 2024-01-10 最終更新日 2024-01-31 実験手法 ELECTRON MICROSCOPY (2.76 Å) 主引用文献 General transcription factor from Escherichia coli with a distinct mechanism of action. Nat.Struct.Mol.Biol., 31, 2024
3IYD	Three-dimensional EM structure of an intact activator-dependent transcription initiation complex 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, DNA (98-MER), ... 著者 Hudson, B.P, Quispe, J, Lara, S, Kim, Y, Berman, H, Arnold, E, Ebright, R.H, Lawson, C.L. 登録日 2009-08-01 公開日 2009-11-10 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (19.799999 Å) 主引用文献 Three-dimensional EM structure of an intact activator-dependent transcription initiation complex Proc.Natl.Acad.Sci.USA, 106, 2009
5TMF	Re-refinement of thermus thermophilus RNA polymerase 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Wang, J. 登録日 2016-10-12 公開日 2016-11-23 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 On the validation of crystallographic symmetry and the quality of structures. Protein Sci., 24, 2015
4LJZ	Crystal Structure Analysis of the E.coli holoenzyme 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Bae, B, Darst, S.A. 登録日 2013-07-05 公開日 2013-11-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.5871 Å) 主引用文献 Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1. Proc.Natl.Acad.Sci.USA, 110, 2013
6EYD	Structure of Mycobacterium smegmatis RNA polymerase Sigma-A holoenzyme 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Kouba, T, Barvik, I, Krasny, L. 登録日 2017-11-11 公開日 2018-12-12 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.22 Å) 主引用文献 The Core and Holoenzyme Forms of RNA Polymerase fromMycobacterium smegmatis. J. Bacteriol., 201, 2019
5X21	Crystal structure of Thermus thermophilus transcription initiation complex with GpA and pseudouridimycin (PUM) 分子名称: (1S)-1,4-anhydro-5-[(N-carbamimidoylglycyl-N~2~-hydroxy-L-glutaminyl)amino]-5-deoxy-1-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-ribitol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Zhang, Y, Ebright, R. 登録日 2017-01-29 公開日 2017-07-05 最終更新日 2022-10-12 実験手法 X-RAY DIFFRACTION (3.323 Å) 主引用文献 Antibacterial Nucleoside-Analog Inhibitor of Bacterial RNA Polymerase. Cell, 169, 2017
5X22	Crystal structure of Thermus thermophilus transcription initiation complex with GpA and CMPcPP 分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Zhang, Y, Ebright, R. 登録日 2017-01-29 公開日 2017-07-05 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Antibacterial Nucleoside-Analog Inhibitor of Bacterial RNA Polymerase. Cell, 169, 2017
4LK0	Crystal Structure Analysis of the E.coli holoenzyme/T7 Gp2 complex 分子名称: Bacterial RNA polymerase inhibitor, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Bae, B, Darst, S.A. 登録日 2013-07-05 公開日 2013-11-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.9103 Å) 主引用文献 Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1. Proc.Natl.Acad.Sci.USA, 110, 2013
6FBV	Single particle cryo em structure of Mycobacterium tuberculosis RNA polymerase in complex with Fidaxomicin 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Das, K, Lin, W, Ebright, E. 登録日 2017-12-19 公開日 2018-02-28 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.52 Å) 主引用文献 Structural Basis of Transcription Inhibition by Fidaxomicin (Lipiarmycin A3). Mol. Cell, 70, 2018
7ZF2	Protomeric substructure from an octameric assembly of M. tuberculosis RNA polymerase in complex with sigma-b initiation factor 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Trapani, S, Bron, P, Lai Kee Him, J, Brodolin, K, Morichaud, Z, Vishwakarma, R. 登録日 2022-03-31 公開日 2023-02-08 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.86 Å) 主引用文献 Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization. Nat Commun, 14, 2023
3UGO	Crystal structure of RNA-polymerase sigma subunit domain 2 complexed with -10 promoter element ssDNA oligo (TACAAT) 分子名称: 5'-D(*TP*GP*TP*AP*CP*AP*AP*TP*GP*GP*G)-3', POTASSIUM ION, RNA polymerase sigma factor 著者 Feklistov, A, Darst, S.A. 登録日 2011-11-02 公開日 2011-12-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.096 Å) 主引用文献 Structural basis for promoter-10 element recognition by the bacterial RNA polymerase sigma subunit. Cell(Cambridge,Mass.), 147, 2011
8AD1	RNA polymerase at U-rich pause bound to RNA putL triple mutant - pause prone, closed clamp state 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Dey, S, Weixlbaumer, A. 登録日 2022-07-07 公開日 2022-10-19 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural insights into RNA-mediated transcription regulation in bacteria. Mol.Cell, 82, 2022
8DY7	Streptomyces venezuelae RNAP transcription open promoter complex with WhiA and WhiB transcription factors 分子名称: DNA (71-MER), DNA (78-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Lilic, M, Campbell, E.A. 登録日 2022-08-03 公開日 2023-03-01 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.18 Å) 主引用文献 Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB. Proc.Natl.Acad.Sci.USA, 120, 2023
8DY9	Streptomyces venezuelae RNAP unconstrained open promoter complex with WhiA and WhiB transcription factors 分子名称: DNA (38-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Lilic, M, Campbell, E.A. 登録日 2022-08-03 公開日 2023-03-01 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.12 Å) 主引用文献 Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB. Proc.Natl.Acad.Sci.USA, 120, 2023
5XJ0	T. thermophilus RNA polymerase holoenzyme bound with gp39 and gp76 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Ooi, W.Y, Murayama, Y, Mekler, V, Minakhin, L, Severinov, K, Yokoyama, S, Sekine, S. 登録日 2017-04-28 公開日 2017-12-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (4.004 Å) 主引用文献 A Thermus phage protein inhibits host RNA polymerase by preventing template DNA strand loading during open promoter complex formation Nucleic Acids Res., 46, 2018
3DXJ	Crystal structure of thermus thermophilus rna polymerase holoenzyme in complex with the antibiotic myxopyronin 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, BACTERIAL RNA POLYMERASE BETA SUBUNIT; CHAIN C, M, ... 著者 Das, K, Arnold, E. 登録日 2008-07-24 公開日 2008-10-14 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The RNA polymerase "switch region" is a target for inhibitors. Cell(Cambridge,Mass.), 135, 2008
2BE5	Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with inhibitor tagetitoxin 分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... 著者 Vassylyev, D.G, Svetlov, V, Vassylyeva, M.N, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Artsimovitch, I, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-10-22 公開日 2005-11-08 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for transcription inhibition by tagetitoxin Nat.Struct.Mol.Biol., 12, 2005
3EQL	Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with antibiotic myxopyronin 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Vassylyev, D.G, Vassylyeva, M.N, Artsimovitch, I. 登録日 2008-09-30 公開日 2008-10-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Transcription inactivation through local refolding of the RNA polymerase structure. Nature, 457, 2009
3UGP	Crystal structure of RNA-polymerase sigma subunit domain 2 complexed with -10 promoter element ssDNA oligo (TATAAT) 分子名称: 5'-D(*TP*GP*TP*AP*TP*AP*AP*TP*GP*GP*G)-3', POTASSIUM ION, RNA polymerase sigma factor 著者 Feklistov, A, Darst, S.A. 登録日 2011-11-02 公開日 2011-12-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.697 Å) 主引用文献 Structural basis for promoter-10 element recognition by the bacterial RNA polymerase sigma subunit. Cell(Cambridge,Mass.), 147, 2011
6B6H	The cryo-EM structure of a bacterial class I transcription activation complex 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Liu, B, Hong, C, Huang, R, Yu, Z, Steitz, T.A. 登録日 2017-10-02 公開日 2017-11-15 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis of bacterial transcription activation. Science, 358, 2017

 

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