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5O0T
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CRYSTAL STRUCTURE OF TRANS-MEMBRANE DOMAIN OF Cylindrospermum stagnale NADPH-OXIDASE 5 (NOX5)
分子名称: DECANE, DI(HYDROXYETHYL)ETHER, EICOSANE, ...
著者Magnani, F, Nenci, S, Mattevi, A.
登録日2017-05-17
公開日2017-06-28
最終更新日2017-07-05
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structures and atomic model of NADPH oxidase.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6Y9B
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BU of 6y9b by Molmil
Cryo-EM structure of trimeric human STEAP1 bound to three Fab120.545 fragments
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, Fab120.545 heavy chain, Fab120.545 light chain, ...
著者Oosterheert, W, Gros, P.
登録日2020-03-06
公開日2020-05-20
最終更新日2020-07-22
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Cryo-electron microscopy structure and potential enzymatic function of human six-transmembrane epithelial antigen of the prostate 1 (STEAP1).
J.Biol.Chem., 295, 2020
8UCD
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BU of 8ucd by Molmil
Cryo-EM structure of human STEAP1 in complex with AMG 509 Fab
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, AMG 509 anti-STEAP1 Fab, heavy chain, ...
著者Li, F, Bailis, J.M, Zhang, H.
登録日2023-09-26
公開日2023-11-22
最終更新日2024-01-24
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献AMG 509 (Xaluritamig), an Anti-STEAP1 XmAb 2+1 T-cell Redirecting Immune Therapy with Avidity-Dependent Activity against Prostate Cancer.
Cancer Discov, 14, 2024
6HD1
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BU of 6hd1 by Molmil
human STEAP4 bound to NADPH, FAD and heme.
分子名称: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Oosterheert, W, van Bezouwen, L.S, Rodenburg, R.N.P, Forster, F, Mattevi, A, Gros, P.
登録日2018-08-17
公開日2018-10-24
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-EM structures of human STEAP4 reveal mechanism of iron(III) reduction.
Nat Commun, 9, 2018
8GZ3
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BU of 8gz3 by Molmil
Structure of human phagocyte NADPH oxidase in the resting state
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 7D5 Fab heavy chain, ...
著者Chen, L, Liu, R.
登録日2022-09-24
公開日2022-12-21
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure of human phagocyte NADPH oxidase in the resting state.
Elife, 11, 2022
6SZ5
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BU of 6sz5 by Molmil
Human calmodulin bound to a peptide of human NADPH oxidase 5
分子名称: CALCIUM ION, Calmodulin-2, NADPH oxidase 5
著者Millana, E, Mattevi, A.
登録日2019-10-02
公開日2019-12-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献On the mechanism of calcium-dependent activation of NADPH oxidase 5 (NOX5).
Febs J., 287, 2020
6HCY
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BU of 6hcy by Molmil
human STEAP4 bound to NADP, FAD, heme and Fe(III)-NTA.
分子名称: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Oosterheert, W, van Bezouwen, L.S, Rodenburg, R.N.P, Forster, F, Mattevi, A, Gros, P.
登録日2018-08-17
公開日2018-10-24
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM structures of human STEAP4 reveal mechanism of iron(III) reduction.
Nat Commun, 9, 2018
7TAI
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BU of 7tai by Molmil
Structure of STEAP2 in complex with ligands
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHOLESTEROL, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Wang, L, Chen, K.H, Zhou, M.
登録日2021-12-20
公開日2023-01-25
最終更新日2024-02-07
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Mechanism of stepwise electron transfer in six-transmembrane epithelial antigen of the prostate (STEAP) 1 and 2.
Elife, 12, 2023
7U8G
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BU of 7u8g by Molmil
Cryo-EM structure of the core human NADPH oxidase NOX2
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 7G5 - heavy chain, ...
著者Noreng, S, Ota, N, Sun, Y, Masureel, M, Payandeh, J, Yi, T, Koerber, J.T.
登録日2022-03-08
公開日2022-10-26
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of the core human NADPH oxidase NOX2.
Nat Commun, 13, 2022
8X2L
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Structure of human phagocyte NADPH oxidase in the resting state in the presence of 2 mM NADPH
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 7D5 Fab heavy chain, 7D5 Fab light chain, ...
著者Chen, L, Liu, X.
登録日2023-11-09
公開日2024-01-24
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献Structure of human phagocyte NADPH oxidase in the activated state.
Nature, 627, 2024
7D3E
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BU of 7d3e by Molmil
Cryo-EM structure of human DUOX1-DUOXA1 in low-calcium state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Dual oxidase 1, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Chen, L, Wu, J.X.
登録日2020-09-19
公開日2020-12-09
最終更新日2021-06-23
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structures of human dual oxidase 1 complex in low-calcium and high-calcium states.
Nat Commun, 12, 2021
7D3F
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BU of 7d3f by Molmil
Cryo-EM structure of human DUOX1-DUOXA1 in high-calcium state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Dual oxidase 1, ...
著者Chen, L, Wu, J.X.
登録日2020-09-19
公開日2020-12-09
最終更新日2021-06-23
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Structures of human dual oxidase 1 complex in low-calcium and high-calcium states.
Nat Commun, 12, 2021
8WEJ
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BU of 8wej by Molmil
Structure of human phagocyte NADPH oxidase in the activated state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 7D5 Fab heavy chain, 7D5 Fab light chain, ...
著者Chen, L, Liu, X.
登録日2023-09-18
公開日2024-01-24
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献Structure of human phagocyte NADPH oxidase in the activated state.
Nature, 627, 2024
6WXV
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BU of 6wxv by Molmil
CryoEM structure of mouse DUOX1-DUOXA1 complex in the presence of NADPH
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
著者Sun, J.
登録日2020-05-12
公開日2020-09-02
最終更新日2021-03-17
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structures of mouse DUOX1-DUOXA1 provide mechanistic insights into enzyme activation and regulation.
Nat.Struct.Mol.Biol., 27, 2020
6WXU
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BU of 6wxu by Molmil
CryoEM structure of mouse DUOX1-DUOXA1 complex in the dimer-of-dimer state
分子名称: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
著者Sun, J.
登録日2020-05-12
公開日2020-09-02
最終更新日2021-03-17
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structures of mouse DUOX1-DUOXA1 provide mechanistic insights into enzyme activation and regulation.
Nat.Struct.Mol.Biol., 27, 2020
6WXR
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BU of 6wxr by Molmil
CryoEM structure of mouse DUOX1-DUOXA1 complex in the absence of NADPH
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Dual oxidase 1, Dual oxidase maturation factor 1, ...
著者Sun, J.
登録日2020-05-11
公開日2020-09-02
最終更新日2021-03-17
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structures of mouse DUOX1-DUOXA1 provide mechanistic insights into enzyme activation and regulation.
Nat.Struct.Mol.Biol., 27, 2020

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件を2024-04-24に公開中

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