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7EXE
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BU of 7exe by Molmil
Crystal structure of mouse 14-3-3zeta in complex with doubly phosphorylated ADAM22 peptide
分子名称: 14-3-3 protein zeta/delta, Disintegrin and metalloproteinase domain-containing protein 22
著者Yan, L, Okatsu, K, Fukai, S.
登録日2021-05-27
公開日2021-11-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献LGI1-ADAM22 levels regulate seizure thresholds through 14-3-3 in mice
Cell Rep, 2021
4QLI
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BU of 4qli by Molmil
A novel phospho-switch in the linker region of the snail zinc finger protein which regulates 14-3-3 association, DNA binding and epithelial-mesenchymal differentiation
分子名称: 14-3-3 protein sigma, GLYCEROL, MAGNESIUM ION, ...
著者Bier, D, Ottmann, C.
登録日2014-06-12
公開日2015-06-17
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献A novel phospho-switch in the linker region of the snail zinc finger protein which regulates 14-3-3 association, DNA binding and epithelial-mesenchymal differentiation
To be Published
8HEW
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BU of 8hew by Molmil
Potato 14-3-3 St14f
分子名称: 14-3-3 protein, StFDL1 peptide
著者Taoka, K, Kawahara, I, Shinya, S, Harada, K, Muranaka, T, Furuita, K, Nakagawa, A, Fujiwara, T, Tsuji, H, Kojima, C.
登録日2022-11-08
公開日2023-09-20
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Multifunctional chemical inhibitors of the florigen activation complex discovered by structure-based high-throughput screening.
Plant J., 112, 2022
7V9B
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BU of 7v9b by Molmil
Crystal Structure of 14-3-3 epsilon with FOXO3a peptide
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-[3,6-bis(dimethylamino)xanthen-9-yl]-5-methanoyl-benzoate, ARG-ARG-ARG-ALA-VAL-SEP-MET-ASP-ASN-SER-ASN, ...
著者Mathivanan, S, Kamariah, N.
登録日2021-08-24
公開日2022-08-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of a 14-3-3 epsilon :FOXO3a pS253 Phosphopeptide Complex Reveals 14-3-3 Isoform-Specific Binding of Forkhead Box Class O Transcription Factor (FOXO) Phosphoproteins.
Acs Omega, 7, 2022
2V7D
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BU of 2v7d by Molmil
14-3-3 protein zeta in complex with Thr758 phosphorylated integrin beta2 peptide
分子名称: 14-3-3 PROTEIN ZETA/DELTA, INTEGRIN BETA CHAIN, BETA 2 VARIANT
著者Takala, H, Ylanne, J.
登録日2007-07-30
公開日2008-06-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Beta2 Integrin Phosphorylation on Thr758 Acts as a Molecular Switch to Regulate 14-3-3 and Filamin Binding.
Blood, 112, 2008
2WH0
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BU of 2wh0 by Molmil
Recognition of an intrachain tandem 14-3-3 binding site within protein kinase C epsilon
分子名称: 14-3-3 PROTEIN ZETA/DELTA, CALCIUM ION, PROTEIN KINASE C EPSILON TYPE, ...
著者Kostelecky, B, Saurin, A.T, Purkiss, A, Parker, P.J, McDonald, N.Q.
登録日2009-04-28
公開日2009-08-18
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Recognition of an Intra-Chain Tandem 14-3-3 Binding Site within Pkc Epsilon.
Embo Rep., 10, 2009
1A37
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BU of 1a37 by Molmil
14-3-3 PROTEIN ZETA BOUND TO PS-RAF259 PEPTIDE
分子名称: 14-3-3 PROTEIN ZETA, PS-RAF259 PEPTIDE LSQRQRST(SEP)TPNVHM
著者Petosa, C, Masters, S.C, Pohl, J, Wang, B, Fu, H, Liddington, R.C.
登録日1998-01-28
公開日1999-03-02
最終更新日2016-08-17
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献14-3-3zeta binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove.
J.Biol.Chem., 273, 1998
1A4O
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BU of 1a4o by Molmil
14-3-3 PROTEIN ZETA ISOFORM
分子名称: 14-3-3 PROTEIN ZETA
著者Liu, D, Bienkowska, J, Petosa, C, Collier, R.J, Fu, H, Liddington, R.C.
登録日1998-02-01
公開日1999-03-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the zeta isoform of the 14-3-3 protein.
Nature, 376, 1995
1A38
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BU of 1a38 by Molmil
14-3-3 PROTEIN ZETA BOUND TO R18 PEPTIDE
分子名称: 14-3-3 PROTEIN ZETA, R18 PEPTIDE (PHCVPRDLSWLDLEANMCLP)
著者Petosa, C, Masters, S.C, Pohl, J, Wang, B, Fu, H, Liddington, R.C.
登録日1998-01-28
公開日1999-03-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献14-3-3zeta binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove.
J.Biol.Chem., 273, 1998
3IQU
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BU of 3iqu by Molmil
Crystal Structure of human 14-3-3 sigma in Complex with Raf1 peptide (6mer)
分子名称: 14-3-3 protein sigma, 6-mer from RAF proto-oncogene serine/threonine-protein kinase, CHLORIDE ION, ...
著者Ottmann, C, Weyand, M.
登録日2009-08-21
公開日2010-09-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling.
Mol.Cell.Biol., 30, 2010
3IQJ
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BU of 3iqj by Molmil
Crystal Structure of human 14-3-3 sigma in Complex with Raf1 peptide (10mer)
分子名称: 10-mer peptide from RAF proto-oncogene serine/threonine-protein kinase, 14-3-3 protein sigma, CHLORIDE ION, ...
著者Ottmann, C, Weyand, M.
登録日2009-08-20
公開日2010-09-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling.
Mol.Cell.Biol., 30, 2010
3IQV
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BU of 3iqv by Molmil
Crystal Structure of human 14-3-3 sigma in Complex with Raf1 peptide (6mer) and stabilisator Fusicoccin
分子名称: 14-3-3 protein sigma, 6-mer peptide from RAF proto-oncogene serine/threonine-protein kinase, CHLORIDE ION, ...
著者Ottmann, C, Weyand, M.
登録日2009-08-21
公開日2010-09-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling.
Mol.Cell.Biol., 30, 2010
5HF3
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BU of 5hf3 by Molmil
Crystal structure of C-terminal modified Tau peptide-hybrid 201D with 14-3-3sigma
分子名称: 14-3-3 protein sigma, modified Tau peptide
著者Bartel, M, Milroy, L.G, Brunsveld, L, Ottmann, C.
登録日2016-01-06
公開日2016-01-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Stabilizer-Guided Inhibition of Protein-Protein Interactions.
Angew.Chem.Int.Ed.Engl., 54, 2015
2NPM
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BU of 2npm by Molmil
crystal structure of Cryptosporidium parvum 14-3-3 protein in complex with peptide
分子名称: 14-3-3 domain containing protein, CONSENSUS PEPTIDE FOR 14-3-3 PROTEINS
著者Dong, A, Lew, J, Wasney, G, Ren, H, Lin, L, Hassanali, A, Qiu, W, Zhao, Y, Doyle, D, Vedadi, M, Koeieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Brokx, S, Structural Genomics Consortium (SGC)
登録日2006-10-27
公開日2006-11-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Characterization of 14-3-3 proteins from Cryptosporidium parvum.
Plos One, 6, 2011
6W0L
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BU of 6w0l by Molmil
Henipavirus W protein interacts with 14-3-3 to modulate host gene expression
分子名称: 14-3-3 protein sigma, CALCIUM ION, Phosphorylated W peptide
著者Edwards, M, Hoad, M, Tsimbalyuk, S, Menicucci, A, Messaoudi, I, Forwood, J, Basler, C.
登録日2020-03-01
公開日2020-04-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Henipavirus W Proteins Interact with 14-3-3 To Modulate Host Gene Expression.
J.Virol., 94, 2020
5IQP
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BU of 5iqp by Molmil
14-3-3 PROTEIN TAU ISOFORM
分子名称: 14-3-3 protein theta, SULFATE ION
著者Xiao, B, Smerdon, S.J, Gamblin, S.J.
登録日2016-03-11
公開日2016-03-23
実験手法X-RAY DIFFRACTION (2.602 Å)
主引用文献Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathways
Nature, 376, 1995
2O98
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BU of 2o98 by Molmil
Structure of the 14-3-3 / H+-ATPase plant complex
分子名称: 14-3-3-like protein C, FUSICOCCIN, Plasma membrane H+ ATPase, ...
著者Ottmann, C, Weyand, M, Wittinghofer, A, Oecking, C.
登録日2006-12-13
公開日2007-04-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of a 14-3-3 coordinated hexamer of the plant plasma membrane H+ -ATPase by combining X-ray crystallography and electron cryomicroscopy
Mol.Cell, 25, 2007
5ULO
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BU of 5ulo by Molmil
Crystal Structure of 14-3-3 zeta in Complex with a Serine 124-phosphorylated TBC1D7 peptide
分子名称: 1,2-ETHANEDIOL, 14-3-3 protein zeta/delta, L-PROLINAMIDE, ...
著者DONG, A, HU, J, MADIGAN, J, WALKER, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, TONG, Y, Structural Genomics Consortium (SGC)
登録日2017-01-25
公開日2018-01-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Crystal Structure of 14-3-3 zeta in Complex with a Serine 124-phosphorylated TBC1D7 peptide
to be published
4N7G
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BU of 4n7g by Molmil
Crystal structure of 14-3-3zeta in complex with a peptide derived from ExoS
分子名称: 14-3-3 protein zeta/delta, Exoenzyme S, HEXAETHYLENE GLYCOL
著者Bier, D, Glas, A, Hahne, G, Grossmann, T, Ottmann, C.
登録日2013-10-15
公開日2014-02-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Constrained peptides with target-adapted cross-links as inhibitors of a pathogenic protein-protein interaction.
Angew.Chem.Int.Ed.Engl., 53, 2014
2O02
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BU of 2o02 by Molmil
Phosphorylation independent interactions between 14-3-3 and Exoenzyme S: from structure to pathogenesis
分子名称: 14-3-3 protein zeta/delta, BENZOIC ACID, ExoS (416-430) peptide
著者Ottmann, C, Yasmin, L, Weyand, M, Hauser, A.R, Wittinghofer, A, Hallberg, B.
登録日2006-11-27
公開日2007-11-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Phosphorylation-independent interaction between 14-3-3 and exoenzyme S: from structure to pathogenesis
Embo J., 26, 2007
4N84
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BU of 4n84 by Molmil
Crystal structure of 14-3-3zeta in complex with a 12-carbon-linker cyclic peptide derived from ExoS
分子名称: 14-3-3 protein zeta/delta, Exoenzyme S
著者Bier, D, Glas, A, Hahne, G, Grossmann, T, Ottmann, C.
登録日2013-10-17
公開日2014-02-19
最終更新日2014-03-12
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Constrained peptides with target-adapted cross-links as inhibitors of a pathogenic protein-protein interaction.
Angew.Chem.Int.Ed.Engl., 53, 2014
2O8P
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BU of 2o8p by Molmil
Crystal structure of a putative 14-3-3 protein from Cryptosporidium parvum, cgd7_2470
分子名称: 14-3-3 domain containing protein
著者Dong, A, Lew, J, Wasney, G, Lin, L, Hassanali, A, Zhao, Y, Vedadi, M, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Walker, J.R, Bochkarev, A, Hui, R, Brokx, S.J, Structural Genomics Consortium (SGC)
登録日2006-12-12
公開日2007-01-09
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Characterization of 14-3-3 proteins from Cryptosporidium parvum.
Plos One, 6, 2011
3CU8
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BU of 3cu8 by Molmil
Impaired binding of 14-3-3 to Raf1 is linked to Noonan and LEOPARD syndrome
分子名称: 14-3-3 protein zeta/delta, MAGNESIUM ION, PROPANOIC ACID, ...
著者Schumacher, B, Weyand, M, Kuhlmann, J, Ottmann, C.
登録日2008-04-16
公開日2009-05-05
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling.
Mol. Cell. Biol., 30, 2010
4N7Y
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BU of 4n7y by Molmil
Crystal structure of 14-3-3zeta in complex with a 8-carbon-linker cyclic peptide derived from ExoS
分子名称: 14-3-3 protein zeta/delta, Exoenzyme S
著者Bier, D, Glas, A, Hahne, G, Grossmann, T, Ottmann, C.
登録日2013-10-16
公開日2014-02-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Constrained peptides with target-adapted cross-links as inhibitors of a pathogenic protein-protein interaction.
Angew.Chem.Int.Ed.Engl., 53, 2014
5J31
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Crystal structure of 14-3-3zeta in complex with an alkyne cross-linked cyclic peptide derived from ExoS
分子名称: 14-3-3 protein zeta/delta, BENZOIC ACID, Exoenzyme S
著者Wallraven, K, Cromm, P, Bier, D, Glas, A, Grossmann, T.
登録日2016-03-30
公開日2016-10-19
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Constraining an Irregular Peptide Secondary Structure through Ring-Closing Alkyne Metathesis.
Chembiochem, 17, 2016

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