7V9B

Crystal Structure of 14-3-3 epsilon with FOXO3a peptide

Summary for 7V9B

Entry DOI	10.2210/pdb7v9b/pdb
Descriptor	YWHAE/FAM22B fusion protein, ARG-ARG-ARG-ALA-VAL-SEP-MET-ASP-ASN-SER-ASN, GLYCEROL, ... (7 entities in total)
Functional Keywords	foxo3a, 14-3-3, 14-3-3 epsilon, protein binding
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	30455.53
Authors	Mathivanan, S.,Kamariah, N. (deposition date: 2021-08-24, release date: 2022-08-31, Last modification date: 2023-11-29)
Primary citation	Mathivanan, S.,Chunchagatta Lakshman, P.K.,Singh, M.,Giridharan, S.,Sathish, K.,Hurakadli, M.A.,Bharatham, K.,Kamariah, N. Structure of a 14-3-3 epsilon :FOXO3a pS253 Phosphopeptide Complex Reveals 14-3-3 Isoform-Specific Binding of Forkhead Box Class O Transcription Factor (FOXO) Phosphoproteins. Acs Omega, 7:24344-24352, 2022 Cited by PubMed: 35874228 DOI: 10.1021/acsomega.2c01700 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation