PDB: 757 件ウェブページステータス検索Chemie searchBIRD

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3ZID	CetZ from Methanosaeta thermophila strain DSM 6194 分子名称: GUANOSINE-5'-DIPHOSPHATE, TUBULIN/FTSZ, GTPASE 著者 Aylett, C.H.S, Amos, L.A, Lowe, J. 登録日 2013-01-08 公開日 2013-08-14 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Cetz Tubulin-Like Proteins Control Archaeal Cell Shape Nature, 519, 2015
9F8G	Photostatin (photoswitchable azo-combretastatin) Z-PST27 bound to tubulin-DARPin D1 complex 分子名称: 5-[(~{Z})-(3,5-diethyl-4-methoxy-phenyl)diazenyl]-2-methyl-phenol, CALCIUM ION, Designed Ankyrin Repeat Protein (DARPIN) D1, ... 著者 Wranik, M, Steinmetz, M.O. 登録日 2024-05-06 公開日 2024-09-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A photo-SAR study of photoswitchable azobenzene tubulin-inhibiting antimitotics identifying a general method for near-quantitative photocontrol. Chem Sci, 15, 2024
4UXT	Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN HEAVY CHAIN ISOFORM 5A, ... 著者 Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. 登録日 2014-08-27 公開日 2014-09-24 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (7.4 Å) 主引用文献 Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins. Elife, 3, 2014
5FNV	a new complex structure of tubulin with an alpha-beta unsaturated lactone 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Wang, Y, Naismith, J, Zhu, X. 登録日 2015-11-16 公開日 2016-05-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Pironetin Reacts Covalently with Cysteine-316 of Alpha-Tubulin to Destabilize Microtubule. Nat.Commun., 7, 2016
6PC4	Tubulin-RB3_SLD-TTL in complex with compound ABI-274 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Kumar, G, Wang, Y, Li, W, White, S.W. 登録日 2019-06-15 公開日 2020-04-22 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.602 Å) 主引用文献 Structure-Activity Relationship Study of Novel 6-Aryl-2-benzoyl-pyridines as Tubulin Polymerization Inhibitors with Potent Antiproliferative Properties. J.Med.Chem., 63, 2020
1OFU	Crystal structure of SulA:FtsZ from Pseudomonas aeruginosa 分子名称: CELL DIVISION PROTEIN FTSZ, GUANOSINE-5'-DIPHOSPHATE, HYPOTHETICAL PROTEIN PA3008 著者 Cordell, S.C, Robinson, E.J.H, Lowe, J. 登録日 2003-04-21 公開日 2003-06-19 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of the SOS Cell Division Inhibitor Sula and in Complex with Ftsz Proc.Natl.Acad.Sci.USA, 100, 2003
6VPP	Cryo-EM structure of microtubule-bound KLP61F motor with tail domain in the nucleotide-free state 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein Klp61F, ... 著者 Bodrug, T, Wilson-Kubalek, E.M, Nithianantham, S, Debs, G, Sindelar, C.V, Milligan, R, Al-Bassam, J. 登録日 2020-02-04 公開日 2020-02-19 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding. Elife, 9, 2020
6I5C	Long wavelength native-SAD phasing of Tubulin-Stathmin-TTL complex 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... 著者 Basu, S, Olieric, V, Matsugaki, N, Kawano, Y, Takashi, T, Huang, C.Y, Leonarski, F, Yamada, Y, Vera, L, Olieric, N, Basquin, J, Wojdyla, J.A, Diederichs, K, Yamamoto, M, Bunk, O, Wang, M. 登録日 2018-11-13 公開日 2019-03-13 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Long-wavelength native-SAD phasing: opportunities and challenges. Iucrj, 6, 2019
8C0F	Tubulin-PTC596 complex 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5-fluoranyl-2-(6-fluoranyl-2-methyl-benzimidazol-1-yl)-~{N}4-[4-(trifluoromethyl)phenyl]pyrimidine-4,6-diamine, ... 著者 Prota, A.E, Muehlethaler, T, Weetall, M, Steinmetz, M.O. 登録日 2022-12-16 公開日 2022-12-28 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1005 Å) 主引用文献 Preclinical and Early Clinical Development of PTC596, a Novel Small-Molecule Tubulin-Binding Agent Mol Cancer Ther, 20, 2021
8C5C	microtubule decorated with tubulin oligomers in presence of APC C-terminal domain. (here only map corresponding to the 13-pf microtubule is represented) 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Serre, L, Arnal, I. 登録日 2023-01-06 公開日 2023-01-25 最終更新日 2023-02-01 実験手法 ELECTRON MICROSCOPY (5.3 Å) 主引用文献 The mitotic role of adenomatous polyposis coli requires its bilateral interaction with tubulin and microtubules. J.Cell.Sci., 136, 2023
6VPO	Cryo-EM structure of microtubule-bound KLP61F motor domain in the AMPPNP state 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein Klp61F, ... 著者 Bodrug, T, Wilson-Kubalek, E.M, Nithianantham, S, Debs, G, Sindelar, C.V, Milligan, R, Al-Bassam, J. 登録日 2020-02-04 公開日 2020-02-19 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding. Elife, 9, 2020
6I2I	Refined 13pf Hela Cell Tubulin microtubule (EML4-NTD decorated) 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... 著者 Atherton, J.M, Moores, C.A. 登録日 2018-11-01 公開日 2019-08-28 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Mitotic phosphorylation by NEK6 and NEK7 reduces the microtubule affinity of EML4 to promote chromosome congression. Sci.Signal., 12, 2019
3RYI	GDP-Tubulin: rb3 stathmin-like domain complex 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Nawrotek, A, Knossow, M, Gigant, B. 登録日 2011-05-11 公開日 2011-10-05 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The Determinants That Govern Microtubule Assembly from the Atomic Structure of GTP-Tubulin. J.Mol.Biol., 412, 2011
3RYC	Tubulin: RB3 stathmin-like domain complex 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Nawrotek, A, Knossow, M, Gigant, B. 登録日 2011-05-11 公開日 2011-10-05 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Determinants That Govern Microtubule Assembly from the Atomic Structure of GTP-Tubulin. J.Mol.Biol., 412, 2011
2HXF	KIF1A head-microtubule complex structure in amppnp-form 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ... 著者 Kikkawa, M, Hirokawa, N. 登録日 2006-08-03 公開日 2006-10-10 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (10 Å) 主引用文献 High-resolution cryo-EM maps show the nucleotide binding pocket of KIF1A in open and closed conformations Embo J., 25, 2006
1JFF	Refined structure of alpha-beta tubulin from zinc-induced sheets stabilized with taxol 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Lowe, J, Li, H, Downing, K.H, Nogales, E. 登録日 2001-06-20 公開日 2001-09-19 最終更新日 2023-08-16 実験手法 ELECTRON CRYSTALLOGRAPHY (3.5 Å) 主引用文献 Refined structure of alpha beta-tubulin at 3.5 A resolution. J.Mol.Biol., 313, 2001
1IA0	KIF1A HEAD-MICROTUBULE COMPLEX STRUCTURE IN ATP-FORM 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-LIKE PROTEIN KIF1A, ... 著者 Kikkawa, M, Sablin, E.P, Okada, Y, Yajima, H, Fletterick, R.J, Hirokawa, N. 登録日 2001-03-22 公開日 2002-03-22 最終更新日 2021-10-27 実験手法 ELECTRON MICROSCOPY (15 Å) 主引用文献 Switch-based Mechanism of Kinesin Motors Nature, 411, 2001
2BTQ	Structure of BtubAB heterodimer from Prosthecobacter dejongeii 分子名称: GUANOSINE-5'-DIPHOSPHATE, SULFATE ION, TUBULIN BTUBA, ... 著者 Schlieper, D, Lowe, J. 登録日 2005-06-06 公開日 2005-06-14 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structure of Bacterial Tubulin Btuba/B: Evidence for Horizontal Gene Transfer. Proc.Natl.Acad.Sci.USA, 102, 2005
2XRP	Human Doublecortin N-DC Repeat (1MJD) and Mammalian Tubulin (1JFF and 3HKE) Docked into the 8-Angstrom Cryo-EM Map of Doublecortin- Stabilised Microtubules 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, NEURONAL MIGRATION PROTEIN DOUBLECORTIN, ... 著者 Fourniol, F.J, Sindelar, C.V, Amigues, B, Clare, D.K, Thomas, G, Perderiset, M, Francis, F, Houdusse, A, Moores, C.A. 登録日 2010-09-18 公開日 2010-11-24 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (8.2 Å) 主引用文献 Template-Free 13-Protofilament Microtubule-Map Assembly Visualized at 8 A Resolution. J.Cell Biol., 191, 2010
3N2K	TUBULIN-NSC 613862: RB3 Stathmin-like domain complex 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Barbier, P, Dorleans, A, Devred, F, Sanz, L, Allegro, D, Alfonso, C, Knossow, M, Peyrot, V, Andreu, J.M. 登録日 2010-05-18 公開日 2010-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Stathmin and interfacial microtubule inhibitors recognize a naturally curved conformation of tubulin dimers. J.Biol.Chem., 285, 2010
1FSZ	CRYSTAL STRUCTURE OF THE CELL-DIVISION PROTEIN FTSZ AT 2.8A RESOLUTION 分子名称: FTSZ, GUANOSINE-5'-DIPHOSPHATE 著者 Lowe, J, Amos, L.A. 登録日 1997-06-24 公開日 1998-06-24 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of the bacterial cell-division protein FtsZ. Nature, 391, 1998
3N2G	TUBULIN-NSC 613863: RB3 Stathmin-like domain complex 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Barbier, P, Dorleans, A, Devred, F, Sanz, L, Allegro, D, Alfonso, C, Knossow, M, Peyrot, V, Andreu, J.M. 登録日 2010-05-18 公開日 2010-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Stathmin and interfacial microtubule inhibitors recognize a naturally curved conformation of tubulin dimers. J.Biol.Chem., 285, 2010
2HXH	KIF1A head-microtubule complex structure in adp-form 分子名称: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Kikkawa, M, Hirokawa, N. 登録日 2006-08-03 公開日 2006-10-10 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (11 Å) 主引用文献 High-resolution cryo-EM maps show the nucleotide binding pocket of KIF1A in open and closed conformations Embo J., 25, 2006
1FFX	TUBULIN:STATHMIN-LIKE DOMAIN COMPLEX 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, PROTEIN (STATHMIN-LIKE DOMAIN OF RB3), ... 著者 Gigant, B, Martin-Barbey, C, Knossow, M. 登録日 2000-07-26 公開日 2000-09-27 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (3.95 Å) 主引用文献 The 4 A X-ray structure of a tubulin:stathmin-like domain complex. Cell(Cambridge,Mass.), 102, 2000
3CB2	Crystal structure of human gamma-tubulin bound to GDP 分子名称: GUANOSINE-5'-DIPHOSPHATE, tubulin gamma-1 chain 著者 Rice, L.M, Montabana, E.A, Agard, D.A. 登録日 2008-02-21 公開日 2008-06-10 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.303 Å) 主引用文献 The lattice as allosteric effector: structural studies of alphabeta- and gamma-tubulin clarify the role of GTP in microtubule assembly Proc.Natl.Acad.Sci.Usa, 105, 2008

 

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