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5A3N
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Crystal structure of human PLU-1 (JARID1B) in complex with KDOAM25a
分子名称: 1,2-ETHANEDIOL, 2-[[[2-[2-(dimethylamino)ethyl-ethyl-amino]-2-oxidanylidene-ethyl]amino]methyl]pyridine-4-carboxamide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Srikannathasan, V, Johansson, C, Gileadi, C, Nuzzi, A, Ruda, G.F, Kopec, J, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Brennan, P, Oppermann, U.
登録日2015-06-02
公開日2015-07-08
最終更新日2017-03-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells.
Cell Chem Biol, 24, 2017
2FSA
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BU of 2fsa by Molmil
Crystal structure of PHD finger-linker-bromodomain fragment of human BPTF in the H3(1-15)K4ME2 bound state
分子名称: Histone H3(1-15)K4me2 peptide, ZINC ION, bromodomain PHD finger transcription factor
著者Li, H, Patel, D.J.
登録日2006-01-21
公開日2006-07-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.
Nature, 442, 2006
3O7A
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Crystal structure of PHF13 in complex with H3K4me3
分子名称: GLYCEROL, H3K4ME3 HISTONE 11MER-PEPTIDE, PHD finger protein 13 variant, ...
著者Bian, C.B, Lam, R, Xu, C, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2010-07-30
公開日2010-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3.
Elife, 5, 2016
5SVX
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BU of 5svx by Molmil
MORC3 CW in complex with histone H3K4me3
分子名称: H3K4me3, MORC family CW-type zinc finger protein 3, ZINC ION
著者Tong, Q, Andrews, F.H, Kutateladze, T.G.
登録日2016-08-08
公開日2016-10-05
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase.
Cell Rep, 16, 2016
2V89
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Crystal structure of RAG2-PHD finger in complex with H3K4me3 peptide at 1.1A resolution
分子名称: HISTONE H3, VDJ RECOMBINATION-ACTIVATING PROTEIN 2, ZINC ION
著者Ramon-Maiques, S, Yang, W.
登録日2007-08-03
公開日2007-12-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Rag2 Phd Finger Couples Histone H3 Lysine 4 Trimethylation with V(D)J Recombination.
Nature, 450, 2007
4L58
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BU of 4l58 by Molmil
Crystal structure of the MLL5 PHD finger in complex with H3K4me3
分子名称: Histone H3 peptide, Histone-lysine N-methyltransferase MLL5, ZINC ION
著者Tong, Q, Ali, M, Kutateladze, T.G.
登録日2013-06-10
公開日2013-06-26
最終更新日2013-07-24
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Molecular basis for chromatin binding and regulation of MLL5.
Proc.Natl.Acad.Sci.USA, 110, 2013
4YHZ
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Crystal structure of 304M3-B Fab in complex with H3K4me3 peptide
分子名称: Fab Heavy Chain, Fab Light Chain, GLYCEROL, ...
著者Hattori, T, Dementieva, I.S, Montano, S.P, Koide, S.
登録日2015-02-27
公開日2016-02-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.304 Å)
主引用文献Antigen clasping by two antigen-binding sites of an exceptionally specific antibody for histone methylation.
Proc.Natl.Acad.Sci.USA, 113, 2016
4L7X
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Crystal structure of the DIDO PHD finger in complex with H3K4me3
分子名称: Death-inducer obliterator 1, Histone H3 peptide, ZINC ION
著者Tong, Q, Gatchalian, J, Kutateladze, T.G.
登録日2013-06-14
公開日2013-07-24
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Dido3 PHD Modulates Cell Differentiation and Division.
Cell Rep, 4, 2013
4MZG
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BU of 4mzg by Molmil
Crystal structure of human Spindlin1 bound to histone H3K4me3 peptide
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ...
著者Su, X, Ding, X, Li, H.
登録日2013-09-30
公開日2014-03-26
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献Molecular basis underlying histone H3 lysine-arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1
Genes Dev., 28, 2014
2V83
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Crystal structure of RAG2-PHD finger in complex with H3K4me3 peptide
分子名称: HISTONE H3, VDJ RECOMBINATION-ACTIVATING PROTEIN 2, ZINC ION
著者Ramon-Maiques, S, Yang, W.
登録日2007-08-02
公開日2007-12-11
最終更新日2019-02-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Plant Homeodomain Finger of Rag2 Recognizes Histone H3 Methylated at Both Lysine-4 and Arginine-2.
Proc.Natl.Acad.Sci.USA, 104, 2007
5TDW
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BU of 5tdw by Molmil
Set3 PHD finger in complex with histone H3K4me3
分子名称: SET domain-containing protein 3, SODIUM ION, ZINC ION, ...
著者Andrews, F.H, Ali, M, Kutateladze, T.G.
登録日2016-09-19
公開日2016-10-19
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Insight into Recognition of Methylated Histone H3K4 by Set3.
J. Mol. Biol., 429, 2017
3MEA
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BU of 3mea by Molmil
Crystal structure of the SGF29 in complex with H3K4me3
分子名称: Histone H3, SAGA-associated factor 29 homolog
著者Bian, C, Xu, C, Tempel, W, MacKenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2010-03-31
公開日2010-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
5YC4
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BU of 5yc4 by Molmil
Crystal structure of AL3 PHD finger bound to H3K4me3
分子名称: Histone H3K4me3, PHD finger protein ALFIN-LIKE 3, ZINC ION
著者Zhao, S, Zhang, B, Li, H.
登録日2017-09-06
公開日2018-01-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.697 Å)
主引用文献Systematic Profiling of Histone Readers in Arabidopsis thaliana.
Cell Rep, 22, 2018
3ME9
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BU of 3me9 by Molmil
Crystal structure of SGF29 in complex with H3K4me3 peptide
分子名称: GLYCEROL, Histone H3, SAGA-associated factor 29 homolog, ...
著者Bian, C, Tempel, W, Xu, C, Guo, Y, Dong, A, Crombet, L, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2010-03-31
公開日2010-04-28
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
3N9O
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BU of 3n9o by Molmil
ceKDM7A from C.elegans, complex with H3K4me3 peptide, H3K9me2 peptide and NOG
分子名称: FE (II) ION, Histone H3 peptide, N-OXALYLGLYCINE, ...
著者Yang, Y, Hu, L, Wang, P, Hou, H, Chen, C.D, Xu, Y.
登録日2010-05-31
公開日2010-06-30
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.309 Å)
主引用文献Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans
Cell Res., 20, 2010
3N9Q
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BU of 3n9q by Molmil
ceKDM7A from C.elegans, complex with H3K4me3 peptide, H3K27me2 peptide and NOG
分子名称: FE (II) ION, Histone H3 peptide, N-OXALYLGLYCINE, ...
著者Yang, Y, Hu, L, Wang, P, Hou, H, Chen, C.D, Xu, Y.
登録日2010-05-31
公開日2010-06-30
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans
Cell Res., 20, 2010
3N9L
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BU of 3n9l by Molmil
ceKDM7A from C.elegans, complex with H3K4me3 peptide and NOG
分子名称: FE (II) ION, Histone H3 peptide, N-OXALYLGLYCINE, ...
著者Yang, Y, Hu, L, Wang, P, Hou, H, Chen, C.D, Xu, Y.
登録日2010-05-31
公開日2010-06-30
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.796 Å)
主引用文献Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans
Cell Res., 20, 2010
3KQI
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BU of 3kqi by Molmil
crystal structure of PHF2 PHD domain complexed with H3K4Me3 peptide
分子名称: CHLORIDE ION, GLYCEROL, H3K4Me3 peptide, ...
著者Wen, H, Li, J.Z, Song, T, Lu, M, Lee, M.
登録日2009-11-17
公開日2010-02-02
最終更新日2019-02-13
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Recognition of histone H3K4 trimethylation by the plant homeodomain of PHF2 modulates histone demethylation.
J.Biol.Chem., 285, 2010
2M3H
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BU of 2m3h by Molmil
Structure of Dido PHD domain
分子名称: Death-inducer obliterator 1, ZINC ION
著者Santiveri, C.M, Perez-Canadillas, J.M, Jimenez, M.
登録日2013-01-19
公開日2013-08-07
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献NMR structure note: PHD domain from death inducer obliterator protein and its interaction with H3K4me3.
J.Biomol.Nmr, 56, 2013
3MP1
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BU of 3mp1 by Molmil
Complex structure of Sgf29 and trimethylated H3K4
分子名称: ACETATE ION, H3K4me3 peptide, Maltose-binding periplasmic protein,LINKER,SAGA-associated factor 29, ...
著者Li, J, Ruan, J, Wu, M, Xue, X, Zang, J.
登録日2010-04-24
公開日2011-05-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation
Embo J., 30, 2011
2K16
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Solution structure of the free TAF3 PHD domain
分子名称: Transcription initiation factor TFIID subunit 3, ZINC ION
著者van Ingen, H, van Schaik, F.M.A, Wienk, H, Timmers, M, Boelens, R.
登録日2008-02-22
公開日2008-07-15
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Recognition of the H3K4me3 mark by the TAF3-PHD finger
To be Published
2YYR
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BU of 2yyr by Molmil
Structural analysis of PHD domain of Pygopus complexed with trimethylated histone H3 peptide
分子名称: H3K4Me3 peptide, Pygopus homolog 1, ZINC ION
著者Nakamura, Y, Padmanabhan, B, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-05-01
公開日2008-05-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural analysis of PHD domain of Pygopus complexed with trimethylated histone H3 peptide
To be Published
4AFL
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The crystal structure of the ING4 dimerization domain reveals the functional organization of the ING family of chromatin binding proteins.
分子名称: INHIBITOR OF GROWTH PROTEIN 4
著者Culurgioni, S, Munoz, I.G, Moreno, A, Palacios, A, Villate, M, Palmero, I, Montoya, G, Blanco, F.J.
登録日2012-01-19
公開日2012-02-22
最終更新日2012-07-11
実験手法X-RAY DIFFRACTION (2.275 Å)
主引用文献Crystal Structure of Inhibitor of Growth 4 (Ing4) Dimerization Domain Reveals Functional Organization of Ing Family of Chromatin-Binding Proteins.
J.Biol.Chem., 287, 2012
3KV5
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Structure of KIAA1718, human Jumonji demethylase, in complex with N-oxalylglycine
分子名称: FE (II) ION, JmjC domain-containing histone demethylation protein 1D, N-OXALYLGLYCINE, ...
著者Horton, J.R, Upadhyay, A.K, Qi, H.H, Zhang, X, Shi, Y, Cheng, X.
登録日2009-11-29
公開日2009-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.
Nat.Struct.Mol.Biol., 17, 2010
3KV9
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Structure of KIAA1718 Jumonji domain
分子名称: FE (II) ION, JmjC domain-containing histone demethylation protein 1D, OXYGEN MOLECULE
著者Horton, J.R, Upadhyay, A.K, Qi, H.H, Zhang, X, Shi, Y, Cheng, X.
登録日2009-11-29
公開日2009-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.
Nat.Struct.Mol.Biol., 17, 2010

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