9UBR
 
 | | CryoEM structure of human Galectin-10 with iTrimbody | | Descriptor: | Galectin-10, PrAC-5350A,2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase, hGal10-nanobody | | Authors: | Song, J.Y, Wang, W. | | Deposit date: | 2025-04-03 | | Release date: | 2026-02-11 | | Method: | ELECTRON MICROSCOPY (2.62 Å) | | Cite: | CryoEM structure of human Galectin-10 with iTrimbody
To Be Published
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9UCL
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9UGK
 | | Crystal Structure of Rv0866 from Mycobacterium tuberculosis | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Molybdopterin synthase catalytic subunit 2 | | Authors: | Cho, H.J, Kang, B.S. | | Deposit date: | 2025-04-12 | | Release date: | 2026-02-11 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural comparison of three MoaE proteins in Mycobacterium tuberculosis: Insights into molybdopterin synthase assembly and specificity.
Biochem.Biophys.Res.Commun., 768, 2025
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9UPC
 | | Structure of human TREX-2 | | Descriptor: | 26S proteasome complex subunit SEM1, Germinal-center associated nuclear protein, PCI domain-containing protein 2 | | Authors: | Zhang, X, Gong, X, Ge, X. | | Deposit date: | 2025-04-28 | | Release date: | 2026-02-11 | | Method: | ELECTRON MICROSCOPY (3.14 Å) | | Cite: | Structure of human TREX-2
To Be Published
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9UXG
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9UXJ
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9UXM
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9VA0
 | | Solution NMR structures of hTERT DNA G-quadruplexes (G4s) in complex with small molecule CPT-11 | | Descriptor: | (4S)-4,11-DIETHYL-4-HYDROXY-3,14-DIOXO-3,4,12,14-TETRAHYDRO-1H-PYRANO[3',4':6,7]INDOLIZINO[1,2-B]QUINOLIN-9-YL 1,4'-BIPIPERIDINE-1'-CARBOXYLATE, DNA (5'-D(*AP*AP*TP*GP*GP*GP*AP*GP*GP*GP*TP*CP*TP*GP*GP*GP*AP*GP*GP*GP*CP*C)-3'), POTASSIUM ION | | Authors: | Zeng, L. | | Deposit date: | 2025-06-02 | | Release date: | 2026-02-11 | | Method: | SOLUTION NMR | | Cite: | Dual Targeting of Topoisomerase I and DNA G-quadruplexes Enhances Senescence Response and Chemosensitivity in Colorectal Cancer Cells
To Be Published
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9VA3
 | | Solution NMR structures of hTERT DNA G-quadruplexes (G4s) in complex with small molecule ZBH-01 | | Descriptor: | (S)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl (2-(4-methylpiperazin-1-yl)-2-oxoethyl)carbamate, DNA (5'-D(*AP*AP*TP*GP*GP*GP*AP*GP*GP*GP*TP*CP*TP*GP*GP*GP*AP*GP*GP*GP*CP*C)-3'), POTASSIUM ION | | Authors: | Zeng, L. | | Deposit date: | 2025-06-02 | | Release date: | 2026-02-11 | | Method: | SOLUTION NMR | | Cite: | Dual Targeting of Topoisomerase I and DNA G-quadruplexes Enhances Senescence Response and Chemosensitivity in Colorectal Cancer Cells
To Be Published
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9VBO
 | | Cryo-EM structure of the multi-component acyltransferase complex MucABC from Streptococcus macacae at a stoichiometric ratio of 4:2:2 | | Descriptor: | 2,4-diacetylphloroglucinol biosynthesis protein PhlB family protein, 3-oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein, 3-oxoacyl-[acyl-carrier-protein (ACP)] synthase III, ... | | Authors: | Luo, Z, Shen, Z, Liao, G, Tang, X, Pan, X. | | Deposit date: | 2025-06-04 | | Release date: | 2026-02-11 | | Method: | ELECTRON MICROSCOPY (2.16 Å) | | Cite: | Evolutionary repurposing of a metabolic thiolase complex enables antibiotic biosynthesis.
Nat Commun, 2026
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9VBT
 | | Cryo-EM structure of the multi-component acyltransferase complex MucABC from Streptococcus macacae at a stoichiometric ratio of 4:4:4 | | Descriptor: | 2,4-diacetylphloroglucinol biosynthesis protein PhlB family protein, 3-oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein, 3-oxoacyl-[acyl-carrier-protein (ACP)] synthase III, ... | | Authors: | Luo, Z, Shen, Z, Liao, G, Tang, X, Pan, X. | | Deposit date: | 2025-06-04 | | Release date: | 2026-02-11 | | Method: | ELECTRON MICROSCOPY (2.32 Å) | | Cite: | Evolutionary repurposing of a metabolic thiolase complex enables antibiotic biosynthesis.
Nat Commun, 2026
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9VLF
 | | Structural studies on the conformation changes induced by ligand binding in an Adenine phosphoribosyltransferase (FnAPRT) from Fusobacterium nucleatum | | Descriptor: | ADENOSINE MONOPHOSPHATE, Adenine phosphoribosyltransferase, PHOSPHATE ION | | Authors: | Kim, B, Hwang, J, Do, H, Lee, J.H. | | Deposit date: | 2025-06-25 | | Release date: | 2026-02-11 | | Method: | X-RAY DIFFRACTION (1.61 Å) | | Cite: | Structural Insights into Ligand-Induced Conformational Changes in Adenine Phosphoribosyl Transferase from Fusobacterium nucleatum.
Protein Pept.Lett., 2026
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9VNU
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9VNV
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9VNW
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9VQ1
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9VTP
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9VTQ
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9VTR
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9VUN
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9VUO
 | | Crystal structure of the DNA/RNA hybrid with Tica | | Descriptor: | 5-[[5-(dimethylamino)thiophen-2-yl]methyl]-N,N-dimethyl-thiophen-2-amine, DNA (5'-D(*CP*GP*TP*CP*TP*CP*CP*AP*GP*GP*CP*AP*AP*C)-3'), RNA (5'-R(*GP*UP*UP*GP*CP*CP*UP*GP*GP*AP*GP*AP*CP*G)-3') | | Authors: | Ren, Y, Huang, L. | | Deposit date: | 2025-07-13 | | Release date: | 2026-02-11 | | Method: | X-RAY DIFFRACTION (2.19 Å) | | Cite: | Unlocking the potential of diarylmethane dyes for living systems
Chem, 2026
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9VWZ
 | | Local refinement region of HPV45 in complex with antibody A16E6 | | Descriptor: | A16E6 Fab heavy chain, A16E6 Fab light chain, Major capsid protein L1 | | Authors: | Jiang, Y, Sun, H, Zheng, Q, Li, S. | | Deposit date: | 2025-07-17 | | Release date: | 2026-02-11 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Cryo-EM structure of human papillomavirus type 45 in complexed with the Fab fragment of 10G2
Structure, 2026
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9VZ8
 | | Local refinement region of HPV45 in complex with antibody 10G2 | | Descriptor: | 10G2 Fab heavy chain, 10G2 Fab light chain, Major capsid protein L1 | | Authors: | Jiang, Y, Sun, H, Zheng, Q, Li, S. | | Deposit date: | 2025-07-22 | | Release date: | 2026-02-11 | | Method: | ELECTRON MICROSCOPY (3.81 Å) | | Cite: | Cryo-EM structure of human papillomavirus type 45 in complexed with the Fab fragment of 10G2
Structure, 2026
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9W3A
 | | Crystal structure of PfiAT toxin-antitoxin complex | | Descriptor: | PfiA protein 1, PfiT protein 1 | | Authors: | Wang, X.X, Chen, R. | | Deposit date: | 2025-07-29 | | Release date: | 2026-02-11 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Phosphorylation of PfiA Modulates Pf4 Phage Production through PfiA/PfiT Stoichiometric Reconfiguration in Pseudomonas aeruginosa
Sci Adv, 2026
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9WGZ
 | | Tryptophan hydroxylase mutant - Y235S | | Descriptor: | FE (III) ION, Tryptophan 5-hydroxylase 1 | | Authors: | Han, J, Liu, F, Rao, Z.M. | | Deposit date: | 2025-08-25 | | Release date: | 2026-02-11 | | Method: | X-RAY DIFFRACTION (1.857 Å) | | Cite: | Structure-Guided Engineering of Tryptophan Hydroxylase Relieves Tunnel Congestion and Substrate Trapping to Enhance 5-Hydroxytryptophan Biosynthesis.
J.Agric.Food Chem., 74, 2026
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