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9VQ1

NMR solution structures of BRD4 ET domain in complex with ASXL1 peptide

Summary for 9VQ1
Entry DOI10.2210/pdb9vq1/pdb
DescriptorBromodomain-containing protein 4, Polycomb group protein ASXL1 (2 entities in total)
Functional Keywordsasxl1, brd4, bap1, et domain, protein binding
Biological sourceHomo sapiens (human)
More
Total number of polymer chains2
Total formula weight11420.25
Authors
Zeng, L.,Zhou, M.-M. (deposition date: 2025-07-04, release date: 2026-02-11)
Primary citationSelvam, K.,Lu, S.,Messmer, C.,Pang, Y.,Biswas, S.,Khalil, M.,Zhang, P.,Lauberth, S.M.,Tulaiha, R.,Zhou, M.-M.,Lauberth, S.M.,Blanco, M.A.,Yang, F.-C.,Affar, E.B.,Zhao, Z.,Zeng, L.,Wang, L.,Kutateladze, T.G.
Recruitment of BRD4 to the ASXL1 genomic targets depends on the extra-terminal domain of BRD4
To Be Published,
Experimental method
SOLUTION NMR
Structure validation

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PDB entries from 2026-02-11

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