9HPI
 
 | | Cryo-EM structure of DDB1dB-CRBN-MRT-0031619, conformation 1 | | Descriptor: | (3~{S})-3-[3-oxidanylidene-5-[8-(phenylcarbonyl)-2,8-diazaspiro[4.5]decan-2-yl]-1~{H}-isoindol-2-yl]piperidine-2,6-dione, DNA damage-binding protein 1, Protein cereblon, ... | | Authors: | Langousis, G, Hunkeler, M, Chami, M, Quan, C, Townson, S, Bonenfant, D. | | Deposit date: | 2024-12-13 | | Release date: | 2025-12-03 | | Method: | ELECTRON MICROSCOPY (2.93 Å) | | Cite: | A degron-mimicking molecular glue drives CRBN homo-dimerization and degradation.
Nat Commun, 16, 2025
|
|
9HPJ
 | | Cryo-EM structure of DDB1dB-CRBN-MRT-0031619, conformation 2 | | Descriptor: | (3~{S})-3-[3-oxidanylidene-5-[8-(phenylcarbonyl)-2,8-diazaspiro[4.5]decan-2-yl]-1~{H}-isoindol-2-yl]piperidine-2,6-dione, DNA damage-binding protein 1, Protein cereblon, ... | | Authors: | Langousis, G, Hunkeler, M, Chami, M, Quan, C, Townson, S, Bonenfant, D. | | Deposit date: | 2024-12-13 | | Release date: | 2025-12-03 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | A degron-mimicking molecular glue drives CRBN homo-dimerization and degradation.
Nat Commun, 16, 2025
|
|
9HYG
 | | Crystal structure of zebrafish S100I1 in Na+-bound form | | Descriptor: | Protein S100, SODIUM ION | | Authors: | Paris, T, Yatime, L. | | Deposit date: | 2025-01-09 | | Release date: | 2025-12-03 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Teleost-specific ictacalcins exhibit similar structural organization, cation-dependent activation and transcriptional regulation as human S100 proteins
Febs J., 2025
|
|
9I0F
 | | Revisited AvNifEN crystal structure | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, FeFe cofactor, ... | | Authors: | Paya Tormo, L, Nguyen, T.Q, Fyfe, C, Basbous, H, Dobrzynska, K, Echavarri-Erasun, C, Martin, L, Caserta, G, Legrand, P, Thorn, A, Amara, P, Schoehn, G, Cherrier, M.V, Rubio, L.M, Nicolet, Y. | | Deposit date: | 2025-01-15 | | Release date: | 2025-12-03 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Dynamics driving the precursor in NifEN scaffold during nitrogenase FeMo-cofactor assembly.
Nat.Chem.Biol., 2025
|
|
9I1G
 | | Crystal structure of zebrafish S100I2 in Mg2+-bound form | | Descriptor: | MAGNESIUM ION, Protein S100 | | Authors: | Demou, M, Yatime, L. | | Deposit date: | 2025-01-16 | | Release date: | 2025-12-03 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Teleost-specific ictacalcins exhibit similar structural organization, cation-dependent activation and transcriptional regulation as human S100 proteins
Febs J., 2025
|
|
9I2M
 | |
9I2N
 | |
9I2P
 | |
9I6F
 | | Cryo-EM structure of HIGD2A bound complex IV | | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CARDIOLIPIN, ... | | Authors: | Nguyen, M.D, Rorbach, J, Singh, V. | | Deposit date: | 2025-01-30 | | Release date: | 2025-12-03 | | Method: | ELECTRON MICROSCOPY (2.95 Å) | | Cite: | Structural basis for late maturation steps of mitochondrial respiratory chain complex IV within the human respirasome
To Be Published
|
|
9I7U
 | | Cryo-EM structure of NDUFA4 bound complex IV within the respirasome complex | | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CARDIOLIPIN, ... | | Authors: | Nguyen, M.D, Singh, V, Rorbach, J. | | Deposit date: | 2025-02-02 | | Release date: | 2025-12-03 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | Structural basis for late maturation steps of mitochondrial respiratory chain complex IV within the human respirasome
To Be Published
|
|
9I8J
 | |
9IBY
 | |
9IC7
 | | Cryo-EM structure of alpha-synuclein fibrils formed in artificial cerebrospinal fluid (aCSF) | | Descriptor: | Alpha-synuclein | | Authors: | Snieckute, R, Sulskis, D, Jocyte, A, Venclovaite, U, Tamulyte, R, Ziaunys, M, Smirnovas, V, Sakalauskas, A. | | Deposit date: | 2025-02-14 | | Release date: | 2025-12-03 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Formation of Condition-Dependent Alpha-Synuclein Fibril Strain in Artificial Cerebrospinal Fluid.
Adv Sci, 2025
|
|
9J6D
 | | Structure of Chikungunya virus infectious particles, 2f block. | | Descriptor: | CHIKV capsid protein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Han, X, Ji, C, Wang, F, Tian, S, Gao, F.G, Yan, J. | | Deposit date: | 2024-08-15 | | Release date: | 2025-12-03 | | Method: | ELECTRON MICROSCOPY (3.11 Å) | | Cite: | Neutralizing antibodies against Chikungunya virus and structural elucidation of their mechanism of action.
Nat Commun, 16, 2025
|
|
9JFK
 | | Cryo-EM structure of [Pen5]-urotensin (4-11)-bounded human Urotensin receptor (UTS2R)-Gq complex | | Descriptor: | ASP-LE1-PHE-TRP-LYS-TYR-CYS-VAL, G subunit q (gi2-mini-gq chimeric), GLYCOCHENODEOXYCHOLIC ACID, ... | | Authors: | Xu, H.E, You, C, Gao, T, Duan, J. | | Deposit date: | 2024-09-04 | | Release date: | 2025-12-03 | | Method: | ELECTRON MICROSCOPY (3.23 Å) | | Cite: | Structural insights into hormone recognition and G-protein coupling of the urotensin-II receptor.
J.Biol.Chem., 301, 2025
|
|
9JG1
 | | Cryo-EM structure of Adriforant-bound Histamine receptor 4 H4R at inactive state | | Descriptor: | Adriforant, Histamine H4 receptor,Soluble cytochrome b562, anti-BRIL Fab Heavy chain, ... | | Authors: | Jin, S.S, Zhang, H, Jiang, Y. | | Deposit date: | 2024-09-05 | | Release date: | 2025-12-03 | | Method: | ELECTRON MICROSCOPY (3.62 Å) | | Cite: | Decoding ligand recognition and constitutive activation of histamine H3 and H4 receptors.
Acta Pharmacol.Sin., 2025
|
|
9K9W
 | | structure of bundle-shaped PBS with short rod | | Descriptor: | Allophycocyanin alpha subunit, Allophycocyanin beta subunit, CpcD protein, ... | | Authors: | Sui, S.-F, Ma, J, You, X, Sun, S. | | Deposit date: | 2024-10-28 | | Release date: | 2025-12-03 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Light-induced structural adaptation of the bundle-shaped phycobilisome from thylakoid-lacking cyanobacterium Gloeobacter violaceus
Nat Commun, 16, 2025
|
|
9KKF
 | | Structure of the human 40S ribosome complexed with HCV IRES and eIF3 | | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | Authors: | Iwasaki, W, Kashiwagi, K, Sakamoto, A, Nishimoto, M, Takahashi, M, Machida, K, Imataka, H, Matsumoto, A, Shichino, Y, Iwasaki, S, Imami, K, Ito, T. | | Deposit date: | 2024-11-13 | | Release date: | 2025-12-03 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural Insights into the Role of eIF3 in Translation Mediated by the HCV IRES
Proc.Natl.Acad.Sci.USA, 2025
|
|
9KN5
 | | Structure of the human 40S ribosome complexed with HCV IRES, eIF1A and eIF3 | | Descriptor: | 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | | Authors: | Iwasaki, W, Kashiwagi, K, Sakamoto, A, Nishimoto, M, Takahashi, M, Machida, K, Imataka, H, Matsumoto, A, Shichino, Y, Iwasaki, S, Imami, K, Ito, T. | | Deposit date: | 2024-11-18 | | Release date: | 2025-12-03 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural Insights into the Role of eIF3 in Translation Mediated by the HCV IRES
Proc.Natl.Acad.Sci.USA, 2025
|
|
9KN6
 | | Structure of the HCV IRES-dependent pre-48S translation initiation complex with eIF1A, eIF5B, and eIF3 | | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | Authors: | Iwasaki, W, Kashiwagi, K, Sakamoto, A, Nishimoto, M, Takahashi, M, Machida, K, Imataka, H, Matsumoto, A, Shichino, Y, Iwasaki, S, Imami, K, Ito, T. | | Deposit date: | 2024-11-18 | | Release date: | 2025-12-03 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural Insights into the Role of eIF3 in Translation Mediated by the HCV IRES
Proc.Natl.Acad.Sci.USA, 2025
|
|
9KQH
 | |
9KQL
 | |
9KQY
 | | The co-crystal structure of DYRK2 with YK-3-18E | | Descriptor: | Dual specificity tyrosine-phosphorylation-regulated kinase 2, [6-[[4-[2-(diethylamino)-1,3-benzothiazol-6-yl]-5-fluoranyl-pyrimidin-2-yl]amino]pyridin-3-yl]-(4-propan-2-ylpiperazin-1-yl)methanone | | Authors: | Tong, C. | | Deposit date: | 2024-11-27 | | Release date: | 2025-12-03 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | The co-crystal structure of DYRK2 with YK-3-18E
To Be Published
|
|
9KRJ
 | | Structure of mouse Dyrk1a | | Descriptor: | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | | Authors: | Kim, K. | | Deposit date: | 2024-11-28 | | Release date: | 2025-12-03 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of mouse Dyrk1a
To Be Published
|
|
9KRP
 | | Structure of the HCV IRES-dependent 48S translation initiation complex with eIF5B and eIF3 | | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | Authors: | Iwasaki, W, Kashiwagi, K, Sakamoto, A, Nishimoto, M, Takahashi, M, Machida, K, Imataka, H, Matsumoto, A, Shichino, Y, Iwasaki, S, Imami, K, Ito, T. | | Deposit date: | 2024-11-28 | | Release date: | 2025-12-03 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural Insights into the Role of eIF3 in Translation Mediated by the HCV IRES
Proc.Natl.Acad.Sci.USA, 2025
|
|
