9G7P
 
 | | Crystal structure of Shewanella putrefaciens PE-like toxin, Spx | | Descriptor: | GLYCEROL, MAGNESIUM ION, Shewanella putrefaciens PE-like toxin catalytically inactive mutant | | Authors: | Masuyer, G. | | Deposit date: | 2024-07-22 | | Release date: | 2025-01-29 | | Method: | X-RAY DIFFRACTION (1.861 Å) | | Cite: | Discovery of Additional Family Members Reveals High Structural Conservation Across Mono-ADP Ribosylating Toxins
To Be Published
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9G9A
 | | CryoEM structure of Enterococcus italicus Csm-crRNA (3.2 complex) | | Descriptor: | CRISPR system Cms endoribonuclease Csm3, CRISPR system Cms protein Csm2, CRISPR system Cms protein Csm4, ... | | Authors: | Jungfer, K, Jinek, M. | | Deposit date: | 2024-07-25 | | Release date: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (2.83 Å) | | Cite: | Mechanistic determinants and dynamics of cA6 synthesis in type III CRISPR-Cas effector complexes.
Nucleic Acids Res., 53, 2025
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9G9B
 | | CryoEM structure of Enterococcus italicus Csm-crRNA (4.3) complex | | Descriptor: | CRISPR system Cms endoribonuclease Csm3, CRISPR system Cms protein Csm2, CRISPR system Cms protein Csm4, ... | | Authors: | Jungfer, K, Jinek, M. | | Deposit date: | 2024-07-25 | | Release date: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (3.07 Å) | | Cite: | Mechanistic determinants and dynamics of cA6 synthesis in type III CRISPR-Cas effector complexes.
Nucleic Acids Res., 53, 2025
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9G9E
 | | CryoEM structure of Enterococcus italicus Csm-crRNA complex bound to AMPNPP | | Descriptor: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, CRISPR system Cms endoribonuclease Csm3, CRISPR system Cms protein Csm2, ... | | Authors: | Jungfer, K, Jinek, M. | | Deposit date: | 2024-07-25 | | Release date: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (2.87 Å) | | Cite: | Mechanistic determinants and dynamics of cA6 synthesis in type III CRISPR-Cas effector complexes.
Nucleic Acids Res., 53, 2025
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9G9F
 | | CryoEM structure of Enterococcus italicus Csm-crRNA-CTR complex bound to AMPNPP | | Descriptor: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, CRISPR system Cms endoribonuclease Csm3, CRISPR system Cms protein Csm2, ... | | Authors: | Jungfer, K, Jinek, M. | | Deposit date: | 2024-07-25 | | Release date: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (2.93 Å) | | Cite: | Mechanistic determinants and dynamics of cA6 synthesis in type III CRISPR-Cas effector complexes.
Nucleic Acids Res., 53, 2025
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9G9G
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9G9H
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9G9I
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9G9J
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9G9K
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9GI7
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9GMK
 | | SIRT7:H3K18DTU nucleosome complex | | Descriptor: | DNA (148-MER), Histone H2A type 2-A, Histone H2B type 1-J, ... | | Authors: | Carlos, M.Y, Babatunde, E, Polina, F, Esther, S, Dongchun, N, Henning, S, Beat, F. | | Deposit date: | 2024-08-29 | | Release date: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structural basis of SIRT7 nucleosome engagement
and substrate specificity
To Be Published
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9GMQ
 | | Crystal structure of the Mpro of SARS COV-2 in complex with the MG-87 inhibitor | | Descriptor: | 3C-like proteinase nsp5, CHLORIDE ION, ~{tert}-butyl ~{N}-[1-[(2~{S})-1-[[(2~{S},3~{R})-4-azanyl-3-oxidanyl-4-oxidanylidene-1-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]butan-2-yl]amino]-3-cyclopropyl-1-oxidanylidene-propan-2-yl]-2-oxidanylidene-pyridin-3-yl]carbamate | | Authors: | El Kilani, H, Hilgenfeld, R. | | Deposit date: | 2024-08-29 | | Release date: | 2025-01-29 | | Method: | X-RAY DIFFRACTION (2.19 Å) | | Cite: | Structure-Based Optimization of Pyridone alpha-Ketoamides as Inhibitors of the SARS-CoV-2 Main Protease.
J.Med.Chem., 2025
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9GMR
 | | SIRT7-H3K36MTUnucleosome complex | | Descriptor: | DNA (149-MER), Histone H2A type 2-A, Histone H2B type 1-J, ... | | Authors: | Carlos, M.Y, Babatunde, E, Polina, F, Esther, S, Dongchun, N, Henning, S, Beat, F. | | Deposit date: | 2024-08-29 | | Release date: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural basis of SIRT7 nucleosome engagement
and substrate specificity
To Be Published
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9GO1
 | | C1C2 Channelrhodopsin - SMX Dark structure | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Archaeal-type opsin 1,Archaeal-type opsin 2, RETINAL | | Authors: | Mulder, M, Weinert, T, Skopintsev, P, Bruenle, S, Broser, M, Hegemann, P, Standfuss, J. | | Deposit date: | 2024-09-04 | | Release date: | 2025-01-29 | | Method: | X-RAY DIFFRACTION (2.59 Å) | | Cite: | Structural Insights Into the Opening Mechanism of C1C2 Channelrhodopsin.
J.Am.Chem.Soc., 147, 2025
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9GO2
 | | C1C2 Channelrhodopsin - SMX Light activated structure | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Archaeal-type opsin 1,Archaeal-type opsin 2, RETINAL | | Authors: | Mulder, M, Weinert, T, Skopintsev, P, Bruenle, S, Broser, M, Hegemann, P, Standfuss, J. | | Deposit date: | 2024-09-04 | | Release date: | 2025-01-29 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural Insights Into the Opening Mechanism of C1C2 Channelrhodopsin.
J.Am.Chem.Soc., 147, 2025
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9GV2
 | | Crystal structure of SARS-CoV-2 main protease (MPro) in complex with the covalently bound inhibitor FP237 (compound 8p in publication) | | Descriptor: | (2S)-2-[2-(3-methoxyphenoxy)ethanoylamino]-4-methyl-N-[(2S)-3-oxidanylidene-1-phenyl-pentan-2-yl]pentanamide, 1,2-ETHANEDIOL, 3C-like proteinase nsp5, ... | | Authors: | Strater, N, Sylvester, K, Muller, C.E, Flury, P, Kruger, N, Breidenbach, J, Guetschow, M, Laufer, S.A, Pillaiyar, T. | | Deposit date: | 2024-09-20 | | Release date: | 2025-01-29 | | Method: | X-RAY DIFFRACTION (2.56 Å) | | Cite: | Design, Synthesis, and Unprecedented Interactions of Covalent Dipeptide-Based Inhibitors of SARS-CoV-2 Main Protease and Its Variants Displaying Potent Antiviral Activity.
J.Med.Chem., 2025
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9GXA
 | | CENP-A/H4 di-tetrasome assembled on alpha-satellite DNA. | | Descriptor: | 147 bp alpha-satellite DNA, 147 bp human alpha-satellite DNA, Histone H3-like centromeric protein A, ... | | Authors: | Ali-Ahmad, A, Sekulic, N. | | Deposit date: | 2024-09-29 | | Release date: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (4.01 Å) | | Cite: | Non-nucleosomal (CENP-A/H4) 2 - DNA complexes as a possible platform for centromere organization.
Biorxiv, 2025
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9GY0
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9H3X
 | | 50S subunit precursor C-CP_H68_L35 | | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L3, 5S ribosomal RNA, ... | | Authors: | Lauer, S, Nikolay, R, Spahn, C.M.T. | | Deposit date: | 2024-10-17 | | Release date: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (4.12 Å) | | Cite: | The proline-rich antimicrobial peptide Api137 disrupts large ribosomal subunit assembly and induces misfolding.
Nat Commun, 16, 2025
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9H8P
 | | Eugenol Oxidase (EUGO) from Rhodococcus jostii RHA1, mutant DTT | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | | Authors: | Rozeboom, H.J, Fraaije, M.W. | | Deposit date: | 2024-10-29 | | Release date: | 2025-01-29 | | Method: | X-RAY DIFFRACTION (1.47 Å) | | Cite: | Biocatalytic Cleavage of para-Acetoxy Benzyl Ethers: Application to Protecting Group Chemistry
Acs Catalysis, 15, 2025
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9HA4
 | | Pooled 50S subunit C-CP_(L22)- precursor states supplemented with Api137 | | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L3, 5S ribosomal RNA, ... | | Authors: | Lauer, S, Nikolay, R, Spahn, C.M.T. | | Deposit date: | 2024-11-01 | | Release date: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (4.26 Å) | | Cite: | The proline-rich antimicrobial peptide Api137 disrupts large ribosomal subunit assembly and induces misfolding.
Nat Commun, 16, 2025
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9HGR
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9HGS
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9HPN
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