9OPZ

Structure of the sweet receptor bound to sucralose in the compact state, extracellular domain

Summary for 9OPZ

• Entry DOI: 10.2210/pdb9opz/pdb
• EMDB information: 70731
• Related PRD ID: PRD_900090
• Descriptor: Taste receptor type 1 member 2, Taste receptor type 1 member 3, 4-chloro-4-deoxy-alpha-D-galactopyranose-(1-2)-1,6-dichloro-1,6-dideoxy-beta-D-fructofuranose (3 entities in total)
• Functional Keywords: membrane protein, gpcr, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 121056.54

Authors

Wang, H.,Chen, X.,Dai, Y.,Lee, C.H. (deposition date: 2025-05-20, release date: 2025-08-27, Last modification date: 2025-11-19)

• Primary citation: Wang, H.,Chen, X.,Dai, Y.,Pidathala, S.,Niu, Y.,Zhao, C.,Li, S.,Wang, L.,Lee, C.H.; Structure and activation mechanism of human sweet taste receptor.; Cell Res., 35:775-778, 2025; PubMed: 40754567; DOI: 10.1038/s41422-025-01156-x

Experimental method

ELECTRON MICROSCOPY (3.16 Å)