9PGO

Cryo-EM structure of brain-derived Tau fibril from Alzheimers disease patient tissue

Summary for 9PGO

• Entry DOI: 10.2210/pdb9pgo/pdb
• EMDB information: 71636
• Descriptor: Microtubule-associated protein tau (1 entity in total)
• Functional Keywords: tau, neurodegeneration, fibril, patient derived, alzheimer's disease, helical reconstruction, amyloid structural protein, protein fibril
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 12
• Total formula weight: 948499.40

Authors

Pierson, J.A.,Sanchez, J.C.,Kraemer, B.C.,Wright, E.R.,Latimer, S.C. (deposition date: 2025-07-08, release date: 2025-08-27)

• Primary citation: Pierson, J.A.,Sanchez, J.C.,Kraemer, B.C.,Wright, E.R.,Latimer, C.S.; Cryo-EM structure of brain-derived Tau fibril from Alzheimers disease patient tissue; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.29 Å)