6WH7
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![BU of 6wh7 by Molmil](/molmil-images/mine/6wh7) | Capsid structure of Penaeus monodon metallodensovirus following EDTA treatment | Descriptor: | Penaeus monodon metallodensovirus major capsid protein | Authors: | Penzes, J.J, Pham, H.T, Chipman, P, Bhattacharya, N, McKenna, R, Agbandje-McKenna, M, Tijssen, P. | Deposit date: | 2020-04-07 | Release date: | 2020-04-22 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.78 Å) | Cite: | Molecular biology and structure of a novel penaeid shrimp densovirus elucidate convergent parvoviral host capsid evolution. Proc.Natl.Acad.Sci.USA, 117, 2020
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6WJD
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6WKS
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![BU of 6wks by Molmil](/molmil-images/mine/6wks) | Structure of SARS-CoV-2 nsp16/nsp10 in complex with RNA cap analogue (m7GpppA) and S-adenosylmethionine | Descriptor: | 1,2-ETHANEDIOL, 2'-O-methyltransferase, ADENOSINE, ... | Authors: | Gupta, Y.K, Viswanathan, T, Arya, S, Qi, S, Misra, A, Chan, S.-H. | Deposit date: | 2020-04-16 | Release date: | 2020-05-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis of RNA cap modification by SARS-CoV-2. Nat Commun, 11, 2020
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6WKV
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![BU of 6wkv by Molmil](/molmil-images/mine/6wkv) | Cryo-EM structure of engineered variant of the Encapsulin from Thermotoga maritima (TmE) | Descriptor: | Encapsulin, FLAVIN MONONUCLEOTIDE | Authors: | Williams, E, Jenkins, M, Zhao, H, Juneja, P, Lutz, S. | Deposit date: | 2020-04-17 | Release date: | 2021-04-21 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.99 Å) | Cite: | Cryo-EM structure of engineered variant of the Encapsulin from Thermotoga maritima (TmE) To Be Published
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6WKX
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![BU of 6wkx by Molmil](/molmil-images/mine/6wkx) | Cryo-EM of Form 1 related peptide filament, 15-10-3 | Descriptor: | peptide 15-10-3 | Authors: | Wang, F, Gnewou, O.M, Egelman, E.H, Conticello, V.P. | Deposit date: | 2020-04-17 | Release date: | 2020-12-02 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials. Nat Commun, 12, 2021
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6WL7
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![BU of 6wl7 by Molmil](/molmil-images/mine/6wl7) | Cryo-EM of Form 2 like peptide filament, 29-20-2 | Descriptor: | peptide 29-20-2 | Authors: | Wang, F, Gnewou, O.M, Modlin, C, Egelman, E.H, Conticello, V.P. | Deposit date: | 2020-04-18 | Release date: | 2020-12-02 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials. Nat Commun, 12, 2021
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6WL8
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![BU of 6wl8 by Molmil](/molmil-images/mine/6wl8) | Cryo-EM of Form 2 peptide filament | Descriptor: | Form 2 peptide | Authors: | Wang, F, Gnewou, O.M, Xu, C, Su, Z, Egelman, E.H, Conticello, V.P. | Deposit date: | 2020-04-18 | Release date: | 2020-12-02 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials. Nat Commun, 12, 2021
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6WL9
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![BU of 6wl9 by Molmil](/molmil-images/mine/6wl9) | Cryo-EM of Form 2 like peptide filament, Form2a | Descriptor: | peptide Form2a | Authors: | Wang, F, Beltran, L.C, Gnewou, O.M, Egelman, E.H, Conticello, V.P. | Deposit date: | 2020-04-18 | Release date: | 2020-12-02 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials. Nat Commun, 12, 2021
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6WLA
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![BU of 6wla by Molmil](/molmil-images/mine/6wla) | Antigen binding fragment of ch128.1 | Descriptor: | Fab ch128.1 heavy chain, Fab ch128.1 light chain, GLYCEROL | Authors: | Helguera, G, Rodriguez, J.A, Sawaya, M, Cascio, D, Zink, S, Ziegenbein, J, Short, C. | Deposit date: | 2020-04-18 | Release date: | 2021-03-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Host receptor-targeted therapeutic approach to counter pathogenic New World mammarenavirus infections. Nat Commun, 13, 2022
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6WNV
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![BU of 6wnv by Molmil](/molmil-images/mine/6wnv) | 70S ribosome without free 5S rRNA and with a perturbed PTC | Descriptor: | 16S ribosomal RNA, 23s-5s joint ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Loveland, A.B, Korostelev, A.A, Mankin, A.S, Huang, S, Aleksashin, N.A, Klepacki, D, Reier, K, Kefi, A, Szal, A, Remme, J, Jaeger, L, Vazquez-Laslop, N. | Deposit date: | 2020-04-23 | Release date: | 2020-06-24 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly. Nat Commun, 11, 2020
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6WNW
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![BU of 6wnw by Molmil](/molmil-images/mine/6wnw) | Active 70S ribosome without free 5S rRNA and bound with A- and P- tRNA | Descriptor: | 16S ribosomal RNA, 23s-5s joint ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Loveland, A.B, Korostelev, A.A, Mankin, A.S, Huang, S, Aleksashin, N.A, Klepacki, D, Reier, K, Kefi, A, Szal, A, Remme, J, Jaeger, L, Vazquez-Laslop, N. | Deposit date: | 2020-04-23 | Release date: | 2020-06-24 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly. Nat Commun, 11, 2020
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6WOO
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![BU of 6woo by Molmil](/molmil-images/mine/6woo) | CryoEM structure of yeast 80S ribosome with Met-tRNAiMet, eIF5B, and GDP | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal rRNA, ... | Authors: | Wang, J, Wang, J, Puglisi, J, Fernandez, I.S. | Deposit date: | 2020-04-25 | Release date: | 2020-09-23 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | An active role of the eukaryotic large ribosomal subunit in translation initiation fidelity. To Be Published
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6WOT
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![BU of 6wot by Molmil](/molmil-images/mine/6wot) | Cryo-EM structure of recombinant rabbit Ryanodine Receptor type 1 mutant R164C in complex with FKBP12.6 | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ZINC ION | Authors: | Iyer, K.A, Hu, Y, Kurebayashi, N, Murayama, T, Samso, M. | Deposit date: | 2020-04-25 | Release date: | 2020-08-05 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM. Sci Adv, 6, 2020
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6WOU
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![BU of 6wou by Molmil](/molmil-images/mine/6wou) | Cryo-EM structure of recombinant mouse Ryanodine Receptor type 2 mutant R176Q in complex with FKBP12.6 in nanodisc | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION | Authors: | Iyer, K.A, Hu, Y, Kurebayashi, N, Murayama, T, Samso, M. | Deposit date: | 2020-04-25 | Release date: | 2020-08-05 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM. Sci Adv, 6, 2020
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6WOV
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![BU of 6wov by Molmil](/molmil-images/mine/6wov) | Cryo-EM structure of recombinant mouse Ryanodine Receptor type 2 wild type in complex with FKBP12.6 | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION | Authors: | Iyer, K.A, Hu, Y, Nayak, A.R, Kurebayashi, N, Murayama, T, Samso, M. | Deposit date: | 2020-04-25 | Release date: | 2020-08-05 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (5.1 Å) | Cite: | Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM. Sci Adv, 6, 2020
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6WS0
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6WS5
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![BU of 6ws5 by Molmil](/molmil-images/mine/6ws5) | Rational drug design of phenazopyridine derivatives as novel inhibitors of Rev1-CT | Descriptor: | 3-[(Z)-(2,3-difluorophenyl)diazenyl]pyridine-2,6-diamine, DNA polymerase zeta catalytic subunit, DNA repair protein REV1, ... | Authors: | McPherson, K.S, Korzhnev, D.M. | Deposit date: | 2020-04-30 | Release date: | 2020-12-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.472 Å) | Cite: | Structure-Based Drug Design of Phenazopyridine Derivatives as Inhibitors of Rev1 Interactions in Translesion Synthesis. Chemmedchem, 16, 2021
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6WXE
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![BU of 6wxe by Molmil](/molmil-images/mine/6wxe) | Cryo-EM reconstruction of VP5*/VP8* assembly from rhesus rotavirus particles - Upright conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Intermediate capsid protein VP6, ... | Authors: | Herrmann, T, Harrison, S.C, Jenni, S. | Deposit date: | 2020-05-10 | Release date: | 2021-01-20 | Last modified: | 2021-03-10 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Functional refolding of the penetration protein on a non-enveloped virus. Nature, 590, 2021
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6WXF
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![BU of 6wxf by Molmil](/molmil-images/mine/6wxf) | Cryo-EM reconstruction of VP5*/VP8* assembly from rhesus rotavirus particles - Intermediate conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Intermediate capsid protein VP6, ... | Authors: | Herrmann, T, Harrison, S.C, Jenni, S. | Deposit date: | 2020-05-10 | Release date: | 2021-01-20 | Last modified: | 2021-03-10 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Functional refolding of the penetration protein on a non-enveloped virus. Nature, 590, 2021
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6WXG
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![BU of 6wxg by Molmil](/molmil-images/mine/6wxg) | Cryo-EM reconstruction of VP5*/VP8* assembly from rhesus rotavirus particles - Reversed conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Intermediate capsid protein VP6, ... | Authors: | Herrmann, T, Harrison, S.C, Jenni, S. | Deposit date: | 2020-05-10 | Release date: | 2021-01-20 | Last modified: | 2021-03-10 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Functional refolding of the penetration protein on a non-enveloped virus. Nature, 590, 2021
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6X02
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6X03
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![BU of 6x03 by Molmil](/molmil-images/mine/6x03) | |
6X2I
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6X2K
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6X32
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![BU of 6x32 by Molmil](/molmil-images/mine/6x32) | Wt pig RyR1 in complex with apoCaM, EGTA condition (class 1 and 2, closed) | Descriptor: | Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor, ... | Authors: | Woll, K.W, Haji-Ghassemi, O, Van Petegem, F. | Deposit date: | 2020-05-21 | Release date: | 2021-01-13 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM. Nat Commun, 12, 2021
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