6YWE
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![BU of 6ywe by Molmil](/molmil-images/mine/6ywe) | The structure of the mitoribosome from Neurospora crassa in the P/E tRNA bound state | Descriptor: | 16S rRNA, 23S rRNA, 3-hydroxyisobutyryl-CoA hydrolase, ... | Authors: | Amunts, A, Itoh, Y, Naschberger, A. | Deposit date: | 2020-04-29 | Release date: | 2020-11-11 | Method: | ELECTRON MICROSCOPY (2.99 Å) | Cite: | Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi. Nat Commun, 11, 2020
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6YWS
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![BU of 6yws by Molmil](/molmil-images/mine/6yws) | The structure of the large subunit of the mitoribosome from Neurospora crassa | Descriptor: | 50S ribosomal protein L14, 50S ribosomal protein L17, 50S ribosomal protein L24, ... | Authors: | Amunts, A, Itoh, Y, Naschberger, A. | Deposit date: | 2020-04-30 | Release date: | 2020-11-11 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.74 Å) | Cite: | Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi. Nat Commun, 11, 2020
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6YWV
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![BU of 6ywv by Molmil](/molmil-images/mine/6ywv) | The structure of the Atp25 bound assembly intermediate of the mitoribosome from Neurospora crassa | Descriptor: | 23 S rRNA, 50S ribosomal protein L14, 50S ribosomal protein L17, ... | Authors: | Amunts, A, Itoh, Y, Naschberger, A. | Deposit date: | 2020-04-30 | Release date: | 2020-11-11 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi. Nat Commun, 11, 2020
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6YWX
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![BU of 6ywx by Molmil](/molmil-images/mine/6ywx) | The structure of the mitoribosome from Neurospora crassa with tRNA bound to the E-site | Descriptor: | 16S rRNA, 23S rRNA, 3-hydroxyisobutyryl-CoA hydrolase, ... | Authors: | Amunts, A, Itoh, Y, Naschberger, A. | Deposit date: | 2020-04-30 | Release date: | 2020-11-11 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi. Nat Commun, 11, 2020
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6YWY
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![BU of 6ywy by Molmil](/molmil-images/mine/6ywy) | The structure of the mitoribosome from Neurospora crassa with bound tRNA at the P-site | Descriptor: | 16S rRNA, 23S rRNA, 3-hydroxyisobutyryl-CoA hydrolase, ... | Authors: | Amunts, A, Itoh, Y, Naschberger, A. | Deposit date: | 2020-04-30 | Release date: | 2020-11-11 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi. Nat Commun, 11, 2020
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6YX7
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![BU of 6yx7 by Molmil](/molmil-images/mine/6yx7) | The high resolution structure of allophycocyanin from cyanobacterium Nostoc sp. WR13, the P21212 crystal form. | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, ... | Authors: | Patel, H.M, Roszak, A.W, Madamwar, D, Cogdell, R.J. | Deposit date: | 2020-04-30 | Release date: | 2021-05-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.419 Å) | Cite: | The high resolution structure of allophycocyanin from cyanobacterium Nostoc sp. WR13 To Be Published
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6YX8
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![BU of 6yx8 by Molmil](/molmil-images/mine/6yx8) | The structure of allophycocyanin from cyanobacterium Nostoc sp. WR13, the C2221 crystal form. | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, ... | Authors: | Patel, H.M, Roszak, A.W, Madamwar, D, Cogdell, R.J. | Deposit date: | 2020-04-30 | Release date: | 2021-05-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.831 Å) | Cite: | The high resolution structure of allophycocyanin from cyanobacterium Nostoc sp. WR13 To Be Published
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6YXL
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![BU of 6yxl by Molmil](/molmil-images/mine/6yxl) | Crystal structure of ACPA F3 | Descriptor: | ACPA F3 Fab fragment - heavy chain, ACPA F3 Fab fragment - light chain, GLYCEROL, ... | Authors: | Ge, C, Holmdahl, R. | Deposit date: | 2020-05-03 | Release date: | 2021-05-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation. Sci Adv, 8, 2022
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6YXM
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![BU of 6yxm by Molmil](/molmil-images/mine/6yxm) | Crystal structure of ACPA 1F2 in complex with CII-C-39-CIT | Descriptor: | ACPA 1F2 Fab fragment - heavy chain, ACPA 1F2 Fab fragment - light chain, CII-C-39-CIT, ... | Authors: | Ge, C, Holmdahl, R. | Deposit date: | 2020-05-03 | Release date: | 2021-05-12 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation. Sci Adv, 8, 2022
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6YXX
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![BU of 6yxx by Molmil](/molmil-images/mine/6yxx) | State A of the Trypanosoma brucei mitoribosomal large subunit assembly intermediate | Descriptor: | 12S ribosomal RNA, 50S ribosomal protein L13, putative, ... | Authors: | Jaskolowski, M, Ramrath, D.J.F, Bieri, P, Niemann, M, Mattei, S, Calderaro, S, Leibundgut, M.A, Horn, E.K, Boehringer, D, Schneider, A, Ban, N. | Deposit date: | 2020-05-04 | Release date: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural Insights into the Mechanism of Mitoribosomal Large Subunit Biogenesis. Mol.Cell, 79, 2020
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6YXY
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![BU of 6yxy by Molmil](/molmil-images/mine/6yxy) | State B of the Trypanosoma brucei mitoribosomal large subunit assembly intermediate | Descriptor: | 12S ribosomal RNA, ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Jaskolowski, M, Ramrath, D.J.F, Bieri, P, Niemann, M, Mattei, S, Calderaro, S, Leibundgut, M.A, Horn, E.K, Boehringer, D, Schneider, A, Ban, N. | Deposit date: | 2020-05-04 | Release date: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural Insights into the Mechanism of Mitoribosomal Large Subunit Biogenesis. Mol.Cell, 79, 2020
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6YXZ
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![BU of 6yxz by Molmil](/molmil-images/mine/6yxz) | |
6YY5
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![BU of 6yy5 by Molmil](/molmil-images/mine/6yy5) | Crystal structure of the ferric enterobactin receptor (PfeA) in complex with TCV_L5 | Descriptor: | FE (III) ION, Ferric enterobactin receptor, ~{N}-[2-[[(2~{S})-3-[[(2~{S})-3-[[1-[2-[2-[2-[4-[4-[5-(acetamidomethyl)-2-oxidanylidene-1,3-oxazolidin-3-yl]-2-fluoranyl-phenyl]piperazin-1-yl]-2-oxidanylidene-ethoxy]ethoxy]ethyl]-1,2,3-triazol-4-yl]methylamino]-2-[[2,3-bis(oxidanyl)phenyl]carbonylamino]-3-oxidanylidene-propyl]amino]-2-[[2,3-bis(oxidanyl)phenyl]carbonylamino]-3-oxidanylidene-propyl]amino]-2-oxidanylidene-ethyl]-2,3-bis(oxidanyl)benzamide | Authors: | Naismith, J.H, Moynie, L.M. | Deposit date: | 2020-05-04 | Release date: | 2020-07-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.717 Å) | Cite: | Hijacking of the Enterobactin Pathway by a Synthetic Catechol Vector Designed for Oxazolidinone Antibiotic Delivery in Pseudomonas aeruginosa. Acs Infect Dis., 2022
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6YYN
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![BU of 6yyn by Molmil](/molmil-images/mine/6yyn) | Structure of Cathepsin S in complex with Compound 14 | Descriptor: | CITRATE ANION, Cathepsin S, SULFATE ION, ... | Authors: | Wagener, M, Schade, M, Merla, B, Hars, U, Kueckelhaus, S.Q. | Deposit date: | 2020-05-05 | Release date: | 2021-05-12 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Highly Selective Sub-Nanomolar Cathepsin S Inhibitors by Merging Fragment Binders with Nitrile Inhibitors. J.Med.Chem., 63, 2020
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6YYO
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![BU of 6yyo by Molmil](/molmil-images/mine/6yyo) | Structure of Cathepsin S in complex with Compound 1 | Descriptor: | 1,2-ETHANEDIOL, 6-(4-methylsulfonylpiperazin-1-yl)-[1,2,4]triazolo[4,3-b]pyridazine, CITRATE ANION, ... | Authors: | Wagener, M, Schade, M, Merla, B, Hars, U, Kueckelhaus, S.Q. | Deposit date: | 2020-05-05 | Release date: | 2021-05-12 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Highly Selective Sub-Nanomolar Cathepsin S Inhibitors by Merging Fragment Binders with Nitrile Inhibitors. J.Med.Chem., 63, 2020
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6YYP
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![BU of 6yyp by Molmil](/molmil-images/mine/6yyp) | Structure of Cathepsin S in complex with Compound 2 | Descriptor: | 1-(furan-2-ylmethyl)-5-(trifluoromethyl)benzimidazol-2-amine, ACETATE ION, Cathepsin S, ... | Authors: | Wagener, M, Schade, M, Merla, B, Hars, U, Kueckelhaus, S.Q. | Deposit date: | 2020-05-05 | Release date: | 2021-05-12 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Highly Selective Sub-Nanomolar Cathepsin S Inhibitors by Merging Fragment Binders with Nitrile Inhibitors. J.Med.Chem., 63, 2020
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6YYQ
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![BU of 6yyq by Molmil](/molmil-images/mine/6yyq) | Structure of Cathepsin S in complex with Compound 3 | Descriptor: | (6~{R})-2-phenyl-5,6,7,8-tetrahydroquinazolin-6-amine, Cathepsin S | Authors: | Wagener, M, Schade, M, Merla, B, Hars, U, Kueckelhaus, S.Q. | Deposit date: | 2020-05-05 | Release date: | 2021-05-12 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Highly Selective Sub-Nanomolar Cathepsin S Inhibitors by Merging Fragment Binders with Nitrile Inhibitors. J.Med.Chem., 63, 2020
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6YYR
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![BU of 6yyr by Molmil](/molmil-images/mine/6yyr) | Structure of Cathepsin S in complex with Compound 20b | Descriptor: | (2~{R})-~{N}-(2-azanylideneethyl)-2-[2-(3-methyl-1,2-oxazol-5-yl)ethanoylamino]-3-(4-pyridin-2-ylpiperazin-1-yl)sulfonyl-propanamide, 1,2-ETHANEDIOL, CITRATE ANION, ... | Authors: | Wagener, M, Schade, M, Merla, B, Hars, U, Kueckelhaus, S.Q. | Deposit date: | 2020-05-05 | Release date: | 2021-05-12 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Highly Selective Sub-Nanomolar Cathepsin S Inhibitors by Merging Fragment Binders with Nitrile Inhibitors. J.Med.Chem., 63, 2020
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6YZ3
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![BU of 6yz3 by Molmil](/molmil-images/mine/6yz3) | PqsR (MvfR) in complex with antagonist 19 | Descriptor: | 1,2-ETHANEDIOL, 6-chloranyl-3-[(2-hexyl-2,3-dihydro-1,3-thiazol-4-yl)methyl]quinazolin-4-one, LysR family transcriptional regulator | Authors: | Richardson, W.K, Emsley, J. | Deposit date: | 2020-05-06 | Release date: | 2020-09-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Novel quinazolinone inhibitors of the Pseudomonas aeruginosa quorum sensing transcriptional regulator PqsR. Eur.J.Med.Chem., 208, 2020
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6YZ7
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![BU of 6yz7 by Molmil](/molmil-images/mine/6yz7) | H11-D4, SARS-CoV-2 RBD, CR3022 ternary complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Cr3022, Antibody light chain, ... | Authors: | Naismith, J.H, Ren, J, Zhou, D, Zhao, Y, Stuart, D.I. | Deposit date: | 2020-05-06 | Release date: | 2020-06-03 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural characterisation of a nanobody derived from a naive library that neutralises SARS-CoV-2 To Be Published, 2020
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6YZD
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![BU of 6yzd by Molmil](/molmil-images/mine/6yzd) | |
6YZF
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![BU of 6yzf by Molmil](/molmil-images/mine/6yzf) | Crystal structure of the M295Y variant of Ssl1 | Descriptor: | COPPER (II) ION, Copper oxidase, GLU-HIS-SER, ... | Authors: | Mielenbrink, S, Olbrich, A, Urlacher, V, Span, I. | Deposit date: | 2020-05-06 | Release date: | 2021-05-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.684 Å) | Cite: | Effect of the axial ligand mutation on spectral and structural properties of Ssl1 laccase To Be Published
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6YZY
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![BU of 6yzy by Molmil](/molmil-images/mine/6yzy) | |
6Z07
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![BU of 6z07 by Molmil](/molmil-images/mine/6z07) | PqsR (MvfR) in complex with antagonist 12 | Descriptor: | 3-[(2-~{tert}-butyl-1,3-thiazol-4-yl)methyl]-6-chloranyl-quinazolin-4-one, GLYCEROL, Transcriptional regulator MvfR | Authors: | Richardson, W.K, Emsley, J. | Deposit date: | 2020-05-07 | Release date: | 2020-09-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Novel quinazolinone inhibitors of the Pseudomonas aeruginosa quorum sensing transcriptional regulator PqsR. Eur.J.Med.Chem., 208, 2020
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6Z0U
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![BU of 6z0u by Molmil](/molmil-images/mine/6z0u) | |