Summary for 6YXL
Entry DOI | 10.2210/pdb6yxl/pdb |
Descriptor | ACPA F3 Fab fragment - heavy chain, ACPA F3 Fab fragment - light chain, GLYCEROL, ... (5 entities in total) |
Functional Keywords | anti-citrullinated protein antibody fab fragment, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 47203.59 |
Authors | Ge, C.,Holmdahl, R. (deposition date: 2020-05-03, release date: 2021-05-12, Last modification date: 2024-01-24) |
Primary citation | Kissel, T.,Ge, C.,Hafkenscheid, L.,Kwekkeboom, J.C.,Slot, L.M.,Cavallari, M.,He, Y.,van Schie, K.A.,Vergroesen, R.D.,Kampstra, A.S.B.,Reijm, S.,Stoeken-Rijsbergen, G.,Koeleman, C.,Voortman, L.M.,Heitman, L.H.,Xu, B.,Pruijn, G.J.M.,Wuhrer, M.,Rispens, T.,Huizinga, T.W.J.,Scherer, H.U.,Reth, M.,Holmdahl, R.,Toes, R.E.M. Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation. Sci Adv, 8:eabm1759-eabm1759, 2022 Cited by PubMed: 35138894DOI: 10.1126/sciadv.abm1759 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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