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6YUT

Structure of recombinant human beta-glucocerebrosidase in complex with N-acyl functionalised cyclophellitol aziridine

This is a non-PDB format compatible entry.
Summary for 6YUT
Entry DOI10.2210/pdb6yut/pdb
Related6YTP 6YTR
DescriptorGlucosylceramidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywordsbeta-glucocerebrosidase, lysosomal glycoside hydrolase, gh30, hydrolase, cyclophellitol aziridine inhibitor, complex
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total formula weight116399.08
Authors
Rowland, R.J.,Davies, G.J. (deposition date: 2020-04-27, release date: 2021-05-12, Last modification date: 2024-01-24)
Primary citationRowland, R.J.,Chen, Y.,Breen, I.,Wu, L.,Offen, W.A.,Beenakker, T.J.,Su, Q.,van den Nieuwendijk, A.M.C.H.,Aerts, J.M.F.G.,Artola, M.,Overkleeft, H.S.,Davies, G.J.
Design, Synthesis and Structural Analysis of Glucocerebrosidase Imaging Agents.
Chemistry, 27:16377-16388, 2021
Cited by
PubMed: 34570911
DOI: 10.1002/chem.202102359
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.76 Å)
Structure validation

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