8FAE
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![BU of 8fae by Molmil](/molmil-images/mine/8fae) | Asymmetric structure of cleaved HIV-1 AE2 envelope glycoprotein trimer in styrene-maleic acid lipid nanoparticles (AE2.1) | Descriptor: | 1-[(2R)-4-(benzenecarbonyl)-2-methylpiperazin-1-yl]-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Wang, K, Zhang, S, Sodroski, J, Mao, Y. | Deposit date: | 2022-11-26 | Release date: | 2023-06-07 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Asymmetric conformations of cleaved HIV-1 envelope glycoprotein trimers in styrene-maleic acid lipid nanoparticles. Commun Biol, 6, 2023
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8FAK
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![BU of 8fak by Molmil](/molmil-images/mine/8fak) | DNA replication fork binding triggers structural changes in the PriA DNA helicase that regulate the PriA-PriB replication restart pathway in E. coli | Descriptor: | DNA (5'-D(P*CP*AP*GP*AP*CP*TP*CP*AP*TP*TP*TP*AP*GP*CP*CP*CP*TP*TP*AP*TP*CP*CP*G)-3'), DNA (5'-D(P*CP*GP*GP*AP*TP*AP*AP*GP*GP*GP*CP*TP*GP*AP*GP*CP*AP*CP*GP*CP*CP*GP*A)-3'), DNA (5'-D(P*TP*CP*GP*GP*CP*GP*TP*GP*CP*TP*C)-3'), ... | Authors: | Duckworth, A.T, Ducos, P.L, McMillan, S.D, Satyshur, K.A, Blumenthal, K.H, Deorio, H.R, Larson, J.A, Sandler, S.J, Grant, T, Keck, J.L. | Deposit date: | 2022-11-28 | Release date: | 2023-05-10 | Last modified: | 2023-05-24 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | Replication fork binding triggers structural changes in the PriA helicase that govern DNA replication restart in E. coli. Nat Commun, 14, 2023
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8FBD
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![BU of 8fbd by Molmil](/molmil-images/mine/8fbd) | Crystal structure of OrfX1-OrfX3 complex from Clostridium botulinum E1 | Descriptor: | ACETATE ION, Neurotoxin complex component Orf-X1, Neurotoxin complex component Orf-X3 | Authors: | Liu, S, Gao, L. | Deposit date: | 2022-11-29 | Release date: | 2022-12-21 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal structures of OrfX1, OrfX2 and the OrfX1-OrfX3 complex from the orfX gene cluster of botulinum neurotoxin E1. Febs Lett., 597, 2023
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8FBF
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![BU of 8fbf by Molmil](/molmil-images/mine/8fbf) | Crystal structure of OrfX2 from Clostridium botulinum E1 | Descriptor: | Neurotoxin complex component Orf-X2, SULFATE ION | Authors: | Lam, K.H, Gao, L. | Deposit date: | 2022-11-29 | Release date: | 2022-12-21 | Last modified: | 2023-03-08 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structures of OrfX1, OrfX2 and the OrfX1-OrfX3 complex from the orfX gene cluster of botulinum neurotoxin E1. Febs Lett., 597, 2023
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8FBL
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![BU of 8fbl by Molmil](/molmil-images/mine/8fbl) | Human PAC in nanodisc at pH 4.0 with PI(4,5)P2 diC8 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Proton-activated chloride channel, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | Authors: | Ruan, Z, Lu, W. | Deposit date: | 2022-11-29 | Release date: | 2023-02-01 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Inhibition of the proton-activated chloride channel PAC by PIP 2. Elife, 12, 2023
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8FBP
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![BU of 8fbp by Molmil](/molmil-images/mine/8fbp) | Glutamine synthetase from Pseudomonas aeruginosa, filament double-unit in compressed conformation | Descriptor: | Glutamine synthetase | Authors: | Phan, I.Q, Staker, B, Shek, R, Moser, T.H, Evans, J.E, van Voorhis, W.C, Myler, P.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | Deposit date: | 2022-11-29 | Release date: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Glutamine synthetase from Pseudomonas aeruginosa, filament double-unit in compressed conformation To Be Published
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8FBT
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![BU of 8fbt by Molmil](/molmil-images/mine/8fbt) | Crystal structure of Cryptosporidium parvum N-myristoyltransferase with bound myristoyl-CoA | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Staker, B.L, Fenwick, M.K, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | Deposit date: | 2022-11-30 | Release date: | 2023-05-31 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Identification of and Structural Insights into Hit Compounds Targeting N -Myristoyltransferase for Cryptosporidium Drug Development. Acs Infect Dis., 9, 2023
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8FBU
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![BU of 8fbu by Molmil](/molmil-images/mine/8fbu) | Crystal structure of Cryptosporidium parvum N-myristoyltransferase with bound myristoyl-CoA and Compound-2 | Descriptor: | (2M)-2-[2-(piperazin-1-yl)phenyl]-N-(1,3-thiazol-2-yl)-1H-benzimidazole-4-carboxamide, 1,2-ETHANEDIOL, CHLORIDE ION, ... | Authors: | Staker, B.L, Fenwick, M.K, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | Deposit date: | 2022-11-30 | Release date: | 2023-05-31 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Identification of and Structural Insights into Hit Compounds Targeting N -Myristoyltransferase for Cryptosporidium Drug Development. Acs Infect Dis., 9, 2023
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8FC1
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![BU of 8fc1 by Molmil](/molmil-images/mine/8fc1) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and erythromycin at 2.50A resolution | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | Authors: | Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S. | Deposit date: | 2022-12-01 | Release date: | 2023-07-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A. Nat Commun, 14, 2023
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8FC2
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![BU of 8fc2 by Molmil](/molmil-images/mine/8fc2) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and azithromycin at 2.50A resolution | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | Authors: | Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S. | Deposit date: | 2022-12-01 | Release date: | 2023-07-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A. Nat Commun, 14, 2023
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8FC3
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![BU of 8fc3 by Molmil](/molmil-images/mine/8fc3) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and telithromycin at 2.60A resolution | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | Authors: | Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S. | Deposit date: | 2022-12-01 | Release date: | 2023-07-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A. Nat Commun, 14, 2023
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8FC4
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![BU of 8fc4 by Molmil](/molmil-images/mine/8fc4) | Crystal structure of the A2058-N6-dimethylated Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and erythromycin at 2.45A resolution | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | Authors: | Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S. | Deposit date: | 2022-12-01 | Release date: | 2023-07-26 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A. Nat Commun, 14, 2023
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8FC5
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![BU of 8fc5 by Molmil](/molmil-images/mine/8fc5) | Crystal structure of the A2058-N6-dimethylated Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and azithromycin at 2.65A resolution | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | Authors: | Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S. | Deposit date: | 2022-12-01 | Release date: | 2023-07-26 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A. Nat Commun, 14, 2023
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8FC6
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![BU of 8fc6 by Molmil](/molmil-images/mine/8fc6) | Crystal structure of the A2058-N6-dimethylated Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and telithromycin at 2.35A resolution | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | Authors: | Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S. | Deposit date: | 2022-12-01 | Release date: | 2023-07-26 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A. Nat Commun, 14, 2023
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8FCG
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![BU of 8fcg by Molmil](/molmil-images/mine/8fcg) | Cryo-EM structure of Chikungunya virus asymmetric unit | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Capsid protein, E1 glycoprotein, ... | Authors: | Su, G.C, Chmielewsk, D, Kaelber, J, Pintilie, G, Chen, M, Jin, J, Auguste, A, Chiu, W. | Deposit date: | 2022-12-01 | Release date: | 2024-03-20 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.09 Å) | Cite: | Cryogenic electron microscopy and tomography reveal imperfect icosahedral symmetry in alphaviruses. Pnas Nexus, 3, 2024
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8FEO
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![BU of 8feo by Molmil](/molmil-images/mine/8feo) | |
8FEP
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![BU of 8fep by Molmil](/molmil-images/mine/8fep) | |
8FEQ
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![BU of 8feq by Molmil](/molmil-images/mine/8feq) | |
8FER
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![BU of 8fer by Molmil](/molmil-images/mine/8fer) | |
8FEX
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![BU of 8fex by Molmil](/molmil-images/mine/8fex) | |
8FIZ
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![BU of 8fiz by Molmil](/molmil-images/mine/8fiz) | Cryo-EM structure of E. coli 70S Ribosome containing mRNA and tRNA (in the transcription-translation complex) | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Florez Ariza, A, Wee, L, Tong, A, Canari, C, Grob, P, Nogales, E, Bustamante, C. | Deposit date: | 2022-12-18 | Release date: | 2023-03-29 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | A trailing ribosome speeds up RNA polymerase at the expense of transcript fidelity via force and allostery. Cell, 186, 2023
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8FJK
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![BU of 8fjk by Molmil](/molmil-images/mine/8fjk) | Golden Shiner Reovirus Core Polar Vertex | Descriptor: | Clamp protein VP6, Major inner capsid protein VP3, Microtubule-associated protein VP5, ... | Authors: | Stevens, A.S, Zhou, Z.H. | Deposit date: | 2022-12-19 | Release date: | 2023-03-22 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Asymmetric reconstruction of the aquareovirus core at near-atomic resolution and mechanism of transcription initiation. Protein Cell, 14, 2023
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8FJL
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![BU of 8fjl by Molmil](/molmil-images/mine/8fjl) | Golden Shiner Reovirus Core Tropical Vertex | Descriptor: | Clamp protein VP6, Major inner capsid protein VP3, Microtubule-associated protein VP5, ... | Authors: | Stevens, A.S, Zhou, Z.H. | Deposit date: | 2022-12-19 | Release date: | 2023-03-08 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | Asymmetric reconstruction of the aquareovirus core at near-atomic resolution and mechanism of transcription initiation. Protein Cell, 14, 2023
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8FK5
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![BU of 8fk5 by Molmil](/molmil-images/mine/8fk5) | Cryo-EM Structure of PG9RSH DU011 Fab in complex with BG505 DS-SOSIP.664 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | Authors: | Gorman, J, Kwong, P.D. | Deposit date: | 2022-12-20 | Release date: | 2023-05-31 | Last modified: | 2023-07-26 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Improved HIV-1 neutralization breadth and potency of V2-apex antibodies by in silico design. Cell Rep, 42, 2023
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8FKJ
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![BU of 8fkj by Molmil](/molmil-images/mine/8fkj) | Yeast ATP Synthase in conformation-3, at pH 6 | Descriptor: | ATP synthase protein 8, ATP synthase subunit 4, mitochondrial, ... | Authors: | Sharma, S, Patel, H, Luo, M, Mueller, D.M, Liao, M. | Deposit date: | 2022-12-21 | Release date: | 2024-01-24 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F 1 -F o coupling. Nat.Struct.Mol.Biol., 31, 2024
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