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coronavirus
Coronavirus, 2020. Modified from the original illustration by David S. Goodsell@RCSB PDB

The recent outbreak of the Novel Coronavirus disease (COVID-19) is a serious threat to people all over the world. In order to understand and develop an effective drug against this virus (Severe Acute Respiratory Syndrome Coronavirus 2: SARS-CoV-2), structural work on the related proteins has already started and the resultant entries are accumulating in the PDB. PDBj provides a portal page for the COVID-19 related entries for our users. New entries will be added simultaneously with the public release from the wwPDB.

An explanation article covering one of the proteins of this virus is available on the "Molecules of the Month" page below:

The tab "All entries" contains all PDB IDs, in case you want to check all independent entries, including group depositions by the same authors. The "Repr. entries" tab contains only representative PDB entries with the highest resolution, excluding duplicate entries with 100% amino acid sequence identitiy, even if they contain a different ligand. Finally, the "Latest entries" tab contains the latest entries released this week.

Created: 2020-10-28 (last edited: more than 1 year ago)2022-09-02
All entries (5197)Repr. entries (2266)Latest entries (44)
8WHU
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Spike Trimer of BA.2.86 in complex with two hACE2s
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Processed angiotensin-converting enzyme 2, ...
Authors:Yue, C, Liu, P.
Deposit date:2023-09-23
Release date:2024-07-03
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity.
Natl Sci Rev, 11, 2024
8WHV
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Spike Trimer of BA.2.86 with three RBDs down
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Yue, C, Liu, P.
Deposit date:2023-09-23
Release date:2024-07-03
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity.
Natl Sci Rev, 11, 2024
8WP8
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Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 RBD in complex with human ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ...
Authors:Li, L.J, Gu, Y.H, Qi, J.X, Gao, G.F.
Deposit date:2023-10-09
Release date:2024-07-03
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 RBD in complex with human ACE2
To Be Published
8X5Q
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SARS-CoV-2 BA.2.75 Spike with K356T mutation (3 RBD down)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Yue, C, Liu, P.
Deposit date:2023-11-17
Release date:2024-07-03
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity.
Natl Sci Rev, 11, 2024
8XLV
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Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 spike protein(6P), 1-RBD-up state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F.
Deposit date:2023-12-26
Release date:2024-07-03
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
8XM5
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Cryo-EM structure of SARS-CoV-2 Omicron EG.5 spike protein(6P), RBD-closed state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F.
Deposit date:2023-12-27
Release date:2024-07-03
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
8XMG
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Cryo-EM structure of SARS-CoV-2 Omicron HV.1 spike protein(6P), RBD-closed state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F.
Deposit date:2023-12-27
Release date:2024-07-03
Last modified:2024-11-27
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
8XMT
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Cryo-EM structure of SARS-CoV-2 Omicron EG.5.1 spike protein(6P), RBD-closed state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F.
Deposit date:2023-12-28
Release date:2024-07-03
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
8XN2
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SARS-CoV-2 Omicron EG.5.1 RBD in complex with human ACE2 (local refined from the spike protein)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ...
Authors:Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F.
Deposit date:2023-12-28
Release date:2024-07-03
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
8XN3
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SARS-CoV-2 Omicron HV.1 RBD in complex with human ACE2 (local refinement from the spike protein)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ...
Authors:Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F.
Deposit date:2023-12-28
Release date:2024-07-03
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
8XN5
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BU of 8xn5 by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron EG.5.1 spike protein(6P) in complex with human ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ...
Authors:Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F.
Deposit date:2023-12-29
Release date:2024-07-03
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
8XNF
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BU of 8xnf by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 spike protein(6P) in complex with human ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F.
Deposit date:2023-12-29
Release date:2024-07-03
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
8XNK
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BU of 8xnk by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron HV.1 spike protein(6P) in complex with human ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ...
Authors:Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F.
Deposit date:2023-12-30
Release date:2024-07-03
Last modified:2024-11-27
Method:ELECTRON MICROSCOPY (2.78 Å)
Cite:Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
8XUS
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BU of 8xus by Molmil
JN.1 Spike Trimer in complex with heparan sulfate
Descriptor: 2-O-sulfo-beta-L-altropyranuronic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Yue, C, Liu, P.
Deposit date:2024-01-14
Release date:2024-07-03
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity.
Natl Sci Rev, 11, 2024
8XUT
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XBB.1.5 Spike Trimer in complex with heparan sulfate
Descriptor: 2-O-sulfo-beta-L-altropyranuronic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Yue, C, Liu, P, Mao, X.
Deposit date:2024-01-14
Release date:2024-07-03
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity.
Natl Sci Rev, 11, 2024
8XUU
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BA.2.86-T356K Spike Trimer in complex with heparan sulfate (Local refinement)
Descriptor: 2-O-sulfo-beta-L-altropyranuronic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Yue, C, Liu, P.
Deposit date:2024-01-14
Release date:2024-07-03
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.69 Å)
Cite:Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity.
Natl Sci Rev, 11, 2024
8XYZ
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BU of 8xyz by Molmil
The structure of fox ACE2 and PT RBD complex
Descriptor: Angiotensin-converting enzyme, Signal peptide, Spike protein S1, ...
Authors:sun, J.Q.
Deposit date:2024-01-20
Release date:2024-07-03
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:The binding and structural basis of fox ACE2 to RBDs from different sarbecoviruses.
Virol Sin, 39, 2024
8Y16
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BU of 8y16 by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron JN.1 spike protein in complex with human ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Li, L.J, Gu, Y.H, Qi, J.X, Gao, G.F.
Deposit date:2024-01-23
Release date:2024-07-03
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
8Y5J
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BU of 8y5j by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron JN.1 spike protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Li, L.J, Gu, Y.H, Qi, J.X, Gao, G.F.
Deposit date:2024-01-31
Release date:2024-07-03
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
8Y6A
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BU of 8y6a by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 RBD in complex with human ACE2 and S309 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Li, L.J, Gu, Y.H, Qi, J.X, Gao, G.F.
Deposit date:2024-02-02
Release date:2024-07-03
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (2.72 Å)
Cite:Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
8YRH
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BU of 8yrh by Molmil
Complex of SARS-CoV-2 main protease and Rosmarinic acid
Descriptor: (2R)-3-(3,4-dihydroxyphenyl)-2-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}propanoic acid, 3C-like proteinase nsp5
Authors:Wang, Q.S, Li, Q.H.
Deposit date:2024-03-21
Release date:2024-07-03
Method:X-RAY DIFFRACTION (1.841 Å)
Cite:Structural basis of rosmarinic acid inhibitory mechanism on SARS-CoV-2 main protease.
Biochem.Biophys.Res.Commun., 724, 2024
8VAO
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BU of 8vao by Molmil
Simulation-driven design of prefusion stabilized SARS-CoV-2 spike S2 antigen
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
Authors:Zhou, L, McLellan, J.S.
Deposit date:2023-12-11
Release date:2024-07-10
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Simulation-driven design of stabilized SARS-CoV-2 spike S2 immunogens.
Nat Commun, 15, 2024
8WZI
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BU of 8wzi by Molmil
One RBD up state of Spike glycoprotein, SARS-CoV-2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yadav, S, Vinothkumar, K.R.
Deposit date:2023-11-01
Release date:2024-07-10
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Factors affecting macromolecule orientations in thin films formed in cryo-EM.
Acta Crystallogr D Struct Biol, 80, 2024
8XG2
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BU of 8xg2 by Molmil
The structure of HLA-A/Pep14
Descriptor: Beta-2-microglobulin, HLA class I heavy chain, Spike protein S1
Authors:Zhang, J.N, Yue, C, Liu, J.
Deposit date:2023-12-14
Release date:2024-07-10
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals.
Immunohorizons, 8, 2024
8XK2
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A neutralizing nanobody VHH60 against wt SARS-CoV-2
Descriptor: Spike protein S1, VHH60 nanobody
Authors:Lu, Y, Guo, H, Ji, X, Yang, H.
Deposit date:2023-12-22
Release date:2024-07-10
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:A broad neutralizing nanobody against SARS-CoV-2 engineered from an approved drug.
Cell Death Dis, 15, 2024

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