8YRH
Complex of SARS-CoV-2 main protease and Rosmarinic acid
Summary for 8YRH
Entry DOI | 10.2210/pdb8yrh/pdb |
Descriptor | 3C-like proteinase nsp5, (2R)-3-(3,4-dihydroxyphenyl)-2-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}propanoic acid (3 entities in total) |
Functional Keywords | sars-cov-2, main protease, rosmarinic acid, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) |
Total number of polymer chains | 2 |
Total formula weight | 66397.78 |
Authors | |
Primary citation | Li, Q.,Zhou, X.,Wang, W.,Xu, Q.,Wang, Q.,Li, J. Structural basis of rosmarinic acid inhibitory mechanism on SARS-CoV-2 main protease. Biochem.Biophys.Res.Commun., 724:150230-150230, 2024 Cited by PubMed: 38865813DOI: 10.1016/j.bbrc.2024.150230 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.841 Å) |
Structure validation
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