8YRH
Complex of SARS-CoV-2 main protease and Rosmarinic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | 3C-like proteinase nsp5 | polymer | 298 | 33018.7 | 2 | UniProt (P0DTD1) Pfam (PF05409) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | 3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase |
| 2 | A | (2R)-3-(3,4-dihydroxyphenyl)-2-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}propanoic acid | non-polymer | 360.3 | 1 | Chemie (ROA) | |||
| 3 | water | water | 18.0 | 271 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 300 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Ala 142 | Asn 3405 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66037.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 360.3 | |
| All* | Total formula weight | 66397.8 |
