8U3O
 
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8ZBQ
 
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9ATO
 
 | XBB.1.5 spike/Nanosota-3C complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanosota-3C, ... | 著者 | Ye, G, Bu, F, Liu, B, Li, F. | 登録日 | 2024-02-27 | 公開日 | 2024-09-18 | 最終更新日 | 2025-04-02 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure-guided in vitro evolution of nanobodies targeting new viral variants. Plos Pathog., 20, 2024
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8WFH
 
 | Crystal structure of Omicron BA.4/5 in complex with a neutralizing antibody scFv D1 | 分子名称: | D1 scFv, Spike protein S1 | 著者 | Terekhov, S.S, Mokrushina, Y.A, Zhang, M, Zhang, N, Gabibov, A, Guo, Y. | 登録日 | 2023-09-19 | 公開日 | 2024-09-25 | 最終更新日 | 2024-11-27 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Crystal structure of Omicron BA.4/5 in complex with a neutralizing antibody scFv D1 To Be Published
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8WFM
 
 | Crystal structure of Omicron BA.1 in complex with a neutralizing antibody scFv T11 | 分子名称: | Spike protein S1, T11 scFv | 著者 | Terekhov, S.S, Mokrushina, Y.A, Zhang, M, Zhang, N, Gabibov, A, Guo, Y. | 登録日 | 2023-09-19 | 公開日 | 2024-09-25 | 最終更新日 | 2024-11-27 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | Crystal structure of Omicron BA.1 in complex with a neutralizing antibody scFv T11 To Be Published
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9DN4
 
 | Crystal structure of a SARS-CoV-2 20-mer RNA in complex with FAB BL3-6S97N | 分子名称: | CHLORIDE ION, FAB BL3-6S97N HEAVY CHAIN, FAB BL3-6S97N LIGHT CHAIN, ... | 著者 | Lovell, S, Cooper, A, Battaile, K.P, Hegde, S, Wang, J. | 登録日 | 2024-09-16 | 公開日 | 2024-09-25 | 最終更新日 | 2025-07-02 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mechanistic studies of small molecule ligands selective to RNA single G bulges. Nucleic Acids Res., 53, 2025
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8WKE
 
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8WSJ
 
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8WSK
 
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8K18
 
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8K19
 
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8WXL
 
 | Structure of the SARS-CoV-2 BA.2.86 spike glycoprotein (closed state) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Yajima, H, Anraku, Y, Kita, S, Kimura, K, Maenaka, K, Hashiguchi, T. | 登録日 | 2023-10-30 | 公開日 | 2024-10-09 | 最終更新日 | 2024-11-06 | 実験手法 | ELECTRON MICROSCOPY (2.59 Å) | 主引用文献 | Structural basis for receptor-binding domain mobility of the spike in SARS-CoV-2 BA.2.86 and JN.1. Nat Commun, 15, 2024
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8XUX
 
 | Structure of the SARS-CoV-2 BA.2.86 spike protein (1-up state) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Yajima, H, Anraku, Y, Kita, S, Kimura, K, Maenaka, K, Hashiguchi, T. | 登録日 | 2024-01-14 | 公開日 | 2024-10-09 | 最終更新日 | 2025-06-18 | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | 主引用文献 | Structural basis for receptor-binding domain mobility of the spike in SARS-CoV-2 BA.2.86 and JN.1. Nat Commun, 15, 2024
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8XV0
 
 | Structure of SARS-CoV-2 BA.2.86 spike RBD in complex with ACE2 (up state) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | 著者 | Yajima, H, Anraku, Y, Kita, S, Kimura, K, Maenaka, K, Hashiguchi, T. | 登録日 | 2024-01-14 | 公開日 | 2024-10-09 | 最終更新日 | 2024-11-27 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis for receptor-binding domain mobility of the spike in SARS-CoV-2 BA.2.86 and JN.1. Nat Commun, 15, 2024
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8XVM
 
 | Structure of SARS-CoV-2 BA.2.86 spike glycoprotein in complex with ACE2 (3-up state) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | 著者 | Yajima, H, Anraku, Y, Kita, S, Kimura, K, Maenaka, K, Hashiguchi, T. | 登録日 | 2024-01-15 | 公開日 | 2024-10-09 | 最終更新日 | 2024-10-23 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | Structural basis for receptor-binding domain mobility of the spike in SARS-CoV-2 BA.2.86 and JN.1. Nat Commun, 15, 2024
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9IU1
 
 | Structure of SARS-CoV-2 JN.1 spike RBD in complex with ACE2 (up state) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | 著者 | Yajima, H, Anraku, Y, Kita, S, Kimura, K, Maenaka, K, Hashiguchi, T. | 登録日 | 2024-07-20 | 公開日 | 2024-10-09 | 最終更新日 | 2024-11-27 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural basis for receptor-binding domain mobility of the spike in SARS-CoV-2 BA.2.86 and JN.1. Nat Commun, 15, 2024
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8WPW
 
 | Cryo-EM structure of SARS-CoV-2 XBB.1.5 receptor-binding domain (RBD) complexed with CB6 mutant,S309, and S304 antibodies | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CB6 fab mutant heavy chain, CB6 fab mutant light chain, ... | 著者 | Su, C, Qi, J.X, Gao, G.F. | 登録日 | 2023-10-10 | 公開日 | 2024-10-16 | 最終更新日 | 2025-07-02 | 実験手法 | ELECTRON MICROSCOPY (2.49 Å) | 主引用文献 | An improved design method enables the ineffective etesevimab broadly and efficiently against SARS-CoV-2 Omicron subvariants To Be Published
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8WPY
 
 | Cryo-EM structure of SARS-CoV-2 receptor-binding domain (RBD) complexed with CB6 mutant,S309, and S304 antibodies | 分子名称: | CB6 fab mutant heavy chain, CB6 fab mutant light chain, S304 fab heavy chain, ... | 著者 | Su, C, Qi, J.X, Gao, G.F. | 登録日 | 2023-10-10 | 公開日 | 2024-10-16 | 最終更新日 | 2025-07-02 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | An improved design method enables the ineffective etesevimab broadly and efficiently against SARS-CoV-2 Omicron subvariants To Be Published
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9ATM
 
 | SARS-CoV-2 EG.5 RBD bound to the VIR-7229 and the S2H97 Fab fragments | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Rietz, T, Park, Y.J, Errico, J, Czudnochowski, N, Nix, J.C, Corti, D, Snell, G, Marco, A.D, Pinto, D, Cameroni, E, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D. | 登録日 | 2024-02-27 | 公開日 | 2024-10-16 | 最終更新日 | 2024-12-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A potent pan-sarbecovirus neutralizing antibody resilient to epitope diversification. Cell, 187, 2024
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9AU1
 
 | SARS-CoV-2 XBB.1.5 RBD bound to the VIR-7229 and the S309 Fab fragments | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Rietz, T, Park, Y.J, Errico, J, Czudnochowski, N, Nix, J.C, Corti, D, Snell, G, Marco, A.D, Pinto, D, Cameroni, E, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D, Structural Genomics Consortium (SGC) | 登録日 | 2024-02-27 | 公開日 | 2024-10-16 | 最終更新日 | 2024-12-25 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | A potent pan-sarbecovirus neutralizing antibody resilient to epitope diversification. Cell, 187, 2024
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9AU2
 
 | VIR-7229 Fab fragment bound the BA.2.86 spike trimer (global refinement) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Tortorici, M.A, Park, Y.J, Veelser, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2024-02-28 | 公開日 | 2024-10-16 | 最終更新日 | 2024-12-25 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | A potent pan-sarbecovirus neutralizing antibody resilient to epitope diversification. Cell, 187, 2024
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9CMN
 
 | Room-temperature X-ray structure of SARS-CoV-2 main protease drug resistant mutant (E166A, L167F) | 分子名称: | 3C-like proteinase nsp5 | 著者 | Kovalevsky, A, Coates, L, Gerlits, O. | 登録日 | 2024-07-15 | 公開日 | 2024-10-16 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Effects of SARS-CoV-2 Main Protease Mutations at Positions L50, E166, and L167 Rendering Resistance to Covalent and Noncovalent Inhibitors. J.Med.Chem., 67, 2024
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9GS4
 
 | SARS-CoV-2 methyltransferase nsp10-16 in complex with SAM and theophylline derivative LAS 54571130 | 分子名称: | 1,2-ETHANEDIOL, 2'-O-methyltransferase nsp16, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | 著者 | Kremling, V, Sprenger, J, Oberthuer, D, Kiene, A. | 登録日 | 2024-09-13 | 公開日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures of SARS-CoV-2 methyltransferase nsp10-16 with Cap0-site binders To Be Published
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8S6M
 
 | SARS-CoV-2 BQ.1.1 RBD bound to the S2V29 and the S2H97 Fab fragments | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Errico, J.M, Park, Y.J, Rietz, T, Czudnochowski, N, Nix, J.C, Cameroni, E, Corti, D, Snell, G, Marco, A.D, Pinto, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D. | 登録日 | 2024-02-28 | 公開日 | 2024-10-23 | 最終更新日 | 2024-12-25 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | A potent pan-sarbecovirus neutralizing antibody resilient to epitope diversification. Cell, 187, 2024
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8VIA
 
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