Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Structural genomics for drug design against the pathogen Coxiella burnetii.
Journal, issue, pages	Proteins, Vol. 83, Page 2124-2136, Year 2015
Publish date	Sep 9, 2011 (structure data deposition date)
Authors	Franklin, M.C. / Cheung, J. / Rudolph, M.J. / Burshteyn, F. / Cassidy, M. / Gary, E. / Hillerich, B. / Yao, Z.K. / Carlier, P.R. / Totrov, M. / Love, J.D.
External links	Proteins / PubMed:26033498
Methods	X-ray diffraction
Resolution	1.5 - 3.298 Å
Structure data	PDB-3tq8: Structure of the dihydrofolate reductase (folA) from Coxiella burnetii in complex with trimethoprim Method: X-RAY DIFFRACTION / Resolution: 1.9 Å PDB-3tq9: Structure of the dihydrofolate reductase (folA) from Coxiella burnetii in complex with methotrexate Method: X-RAY DIFFRACTION / Resolution: 2.3 Å PDB-3tqa: Structure of the dihydrofolate reductase (folA) from Coxiella burnetii in complex with NADPH Method: X-RAY DIFFRACTION / Resolution: 2.3 Å PDB-3tqb: Structure of the dihydrofolate reductase (folA) from Coxiella burnetii in complex with folate Method: X-RAY DIFFRACTION / Resolution: 2.4 Å PDB-3tqc: Structure of the pantothenate kinase (coaA) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2.3 Å PDB-3tqd: Structure of the 3-deoxy-D-manno-octulosonate cytidylyltransferase (kdsB) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 1.8 Å PDB-3tqe: Structure of the malonyl CoA-acyl carrier protein transacylase (fabD) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 1.5 Å PDB-3tqf: Structure of the Hpr(Ser) kinase/phosphatase from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2.8 Å PDB-3tqg: Structure of the 2-methylcitrate synthase (prpC) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2.3 Å PDB-3tqh: Structure of the quinone oxidoreductase from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2.44 Å PDB-3tqi: Structure of the GMP synthase (guaA) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2.84 Å PDB-3tqj: Structure of the superoxide dismutase (Fe) (sodB) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2.004 Å PDB-3tql: Structure of the amino acid ABC transporter, periplasmic amino acid-binding protein from Coxiella burnetii. Method: X-RAY DIFFRACTION / Resolution: 1.594 Å PDB-3tqm: Structure of an ribosomal subunit interface protein from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2.45 Å PDB-3tqn: Structure of the transcriptional regulator of the GntR family, from Coxiella burnetii. Method: X-RAY DIFFRACTION / Resolution: 2.8 Å PDB-3tqo: Structure of the cysteinyl-tRNA synthetase (cysS) from Coxiella burnetii. Method: X-RAY DIFFRACTION / Resolution: 2.3 Å PDB-3tqp: Structure of an enolase (eno) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2.2 Å PDB-3tqq: Structure of the methionyl-tRNA formyltransferase (fmt) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2 Å PDB-3tqr: Structure of the phosphoribosylglycinamide formyltransferase (purN) in complex with CHES from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 1.97 Å PDB-3tqs: Structure of the dimethyladenosine transferase (ksgA) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 1.98 Å PDB-3tqt: Structure of the D-alanine-D-alanine ligase from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 1.88 Å PDB-3tqu: Structure of a HAM1 protein from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 1.9 Å PDB-3tqw: Structure of a ABC transporter, periplasmic substrate-binding protein from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2 Å PDB-3tqx: Structure of the 2-amino-3-ketobutyrate coenzyme A ligase (kbl) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2.304 Å PDB-3tqy: Structure of a single-stranded DNA-binding protein (ssb), from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2.6001 Å PDB-3tqz: Structure of a deoxyuridine 5'-triphosphate nucleotidohydrolase (dut) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 1.75 Å PDB-3tr0: Structure of guanylate kinase (gmk) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 1.851 Å PDB-3tr1: Structure of a 3-phosphoshikimate 1-carboxyvinyltransferase (aroA) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2 Å PDB-3tr2: Structure of a orotidine 5'-phosphate decarboxylase (pyrF) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2.001 Å PDB-3tr3: Structure of a bolA protein homologue from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2.456 Å PDB-3tr4: Structure of an inorganic pyrophosphatase (ppa) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2 Å PDB-3tr5: Structure of a peptide chain release factor 3 (prfC) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2.11 Å PDB-3tr6: Structure of a O-methyltransferase from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2.7 Å PDB-3tr7: Structure of a uracil-DNA glycosylase (ung) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2.1958 Å PDB-3tr8: Structure of an oligoribonuclease (orn) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2.503 Å PDB-3tr9: Structure of a dihydropteroate synthase (folP) in complex with pteroic acid from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 1.895 Å PDB-3trb: Structure of an addiction module antidote protein of a HigA (higA) family from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2.001 Å PDB-3trc: Structure of the GAF domain from a phosphoenolpyruvate-protein phosphotransferase (ptsP) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 1.65 Å PDB-3trd: Structure of an alpha-beta serine hydrolase homologue from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 1.5 Å PDB-3tre: Structure of a translation elongation factor P (efp) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2.899 Å PDB-3trf: Structure of a shikimate kinase (aroK) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2.6 Å PDB-3trg: Structure of an acylphosphatase from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 1.601 Å PDB-3trh: Structure of a phosphoribosylaminoimidazole carboxylase catalytic subunit (purE) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2.203 Å PDB-3tri: Structure of a pyrroline-5-carboxylate reductase (proC) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2.5 Å PDB-3tth: Structure of the spermidine N1-acetyltransferase (speG) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 3.298 Å PDB-3ty2: Structure of a 5'-nucleotidase (surE) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 1.885 Å PDB-3uwc: Structure of an aminotransferase (DegT-DnrJ-EryC1-StrS family) from Coxiella burnetii in complex with PMP Method: X-RAY DIFFRACTION / Resolution: 1.8 Å PDB-4f3q: Structure of a YebC family protein (CBU_1566) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2.15 Å PDB-4f3r: Structure of phosphopantetheine adenylyltransferase (CBU_0288) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2.25 Å PDB-4nbq: Structure of the polynucleotide phosphorylase (CBU_0852) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2.9138 Å PDB-4ng4: Structure of phosphoglycerate kinase (CBU_1782) from Coxiella burnetii Method: X-RAY DIFFRACTION / Resolution: 2.78 Å
Chemicals	ChemComp-NDP: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE ChemComp-TOP: TRIMETHOPRIM / antibioticYM ChemComp-HOH: WATER ChemComp-MTX: METHOTREXATE / chemotherapyYM ChemComp-FOL: FOLIC ACID ChemComp-ADP: ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying moleculeYM ChemComp-NI: NICKEL (II) ION ChemComp-ACT: ACETATE ION ChemComp-GLY: GLYCINE ChemComp-EDO: 1,2-ETHANEDIOL ChemComp-PO4: PHOSPHATE ION ChemComp-SO4: SULFATE ION ChemComp-FE2: Unknown entry ChemComp-ARG: ARGININE ChemComp-IMD: IMIDAZOLE ChemComp-ZN: Unknown entry ChemComp-MG: Unknown entry ChemComp-K: Unknown entry ChemComp-NHE: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID / pH bufferYM ChemComp-CL: Unknown entry ChemComp-CA: Unknown entry ChemComp-MET: METHIONINE ChemComp-PLP: PYRIDOXAL-5'-PHOSPHATE ChemComp-5GP: GUANOSINE-5'-MONOPHOSPHATE ChemComp-CO: Unknown entry ChemComp-MN: Unknown entry ChemComp-GDP: GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying moleculeYM ChemComp-SAH: S-ADENOSYL-L-HOMOCYSTEINE ChemComp-PT1: PTEROIC ACID ChemComp-NA: Unknown entry ChemComp-NAP: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE ChemComp-TRS: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH bufferYM ChemComp-DIO: 1,4-DIETHYLENE DIOXIDE ChemComp-PMP: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE
Source	coxiella burnetii (bacteria)
Keywords	OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR / dihydrofolate reductase / OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex / OXIDOREDUCTASE / TRANSFERASE / Biosynthesis of cofactors / prosthetic groups / carriers / Cell envelope / Fatty acid/phospholipid metabolism / HYDROLASE / Energy metabolism / quinone oxidoreductase / LIGASE / GMP synthase / superoxide dismutase (Fe) / TRANSPORT PROTEIN / Transport and binding proteins / PROTEIN BINDING / Protein synthesis / TRANSCRIPTION / Regulatory functions / LYASE / Purines / pyrimidines / nucleosides / nucleotides / HAM1 protein / DNA replication / Amino acid biosynthesis / UNKNOWN FUNCTION / Cellular processes / stress-induced / Central intermediary metabolism / TRANSLATION / DNA metabolism / and carriers / DNA BINDING PROTEIN / Mobile and extrachromosomal element functions / Signal transduction / Fatty acid and phospholipid metabolism / survival protein / phosphatase / lipopolysaccharide biosynthesis / YebC family / phosphopantetheine adenylyltranferase / Phosphorylase / phosphoglycerate kinase