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Showing 1 - 50 of 72 items for (author: yeeles & jtp)

EMDB-50222:
Human DNA polymerase epsilon bound to DNA and PCNA (open conformation)

EMDB-50223:
Human DNA polymerase epsilon bound to DNA and PCNA (ajar conformation)

EMDB-50224:
Human DNA polymerase epsilon bound to DNA and PCNA (closed conformation)

EMDB-50225:
Human DNA Polymerase epsilon bound to T-C mismatched DNA (Post-Insertion state)

EMDB-50226:
Human DNA Polymerase epsilon bound to T-C mismatched DNA (Polymerase Arrest state)

EMDB-50227:
Human DNA Polymerase epsilon bound to T-C mismatched DNA (Frayed Substrate state)

EMDB-50228:
Human DNA Polymerase epsilon bound to T-C mismatched DNA (Mismatch Excision state)

EMDB-17198:
Cryo-EM density map of the C. elegans complex CMG helicase/TIM-1/TIPN-1/DNSN-1 dimer on fork DNA (prior to enrichment of particles containing TIM-1/TIPN-1)

EMDB-17199:
Cryo-EM density map of the C. elegans complex CMG helicase/TIM-1/TIPN-1/DNSN-1 dimer on fork DNA (Multi-body Refinement DNSN-1 homodimer)

EMDB-17200:
Cryo-EM density map of the C. elegans complex CMG helicase/TIM-1/TIPN-1/DNSN-1 dimer on fork DNA (Multi-body Refinement GINS/CDC-45/DNSN-1 N-terminus)

EMDB-17201:
Cryo-EM density map of the C. elegans complex CMG helicase/TIM-1/TIPN-1/DNSN-1 dimer on fork DNA (Multi-body Refinement MCM-2-7 AAA+/ssDNA)

EMDB-17202:
Cryo-EM density map of the C. elegans complex CMG helicase/TIM-1/TIPN-1/DNSN-1 dimer on fork DNA (Multi-body Refinement MCM-2-7 NTDs)

EMDB-17203:
Cryo-EM density map of the C. elegans complex CMG helicase/TIM-1/TIPN-1/DNSN-1 dimer on fork DNA (Multi-body Refinement TIM-1/TIPN-1/MCM-2-7 NTD/dsDNA)

EMDB-17204:
Cryo-EM structure of CMG helicase bound to TIM-1/TIPN-1 and homodimeric DNSN-1 on fork DNA (Caenorhabditis elegans)

EMDB-15924:
S. cerevisiae pol alpha - replisome complex

EMDB-15309:
Pol alpha - replisome complex containing Ctf4. Engaged on a DNA fork containing a 60 nucleotide lagging strand.

EMDB-15902:
S. cerevisiae replisome + Ctf4 + pol alpha. Unbinned, locally filtered.

EMDB-15904:
Composite map - human replisome + Pol alpha

EMDB-15918:
Human replisome + pol alpha. Not engaged on DNA.

EMDB-15922:
Human replisome bound to pol alpha engaged on a DNA fork substrate containing a 15 nucleotide lagging strand.

EMDB-15923:
Human replisome prepared in the presence of a fork DNA substrate containing a 60 nucleotide lagging strand. Off DNA.

EMDB-16247:
Local refinement, Pri1:Pri2-CTD. Pol alpha primase associated budding yeast replisome.

EMDB-16248:
Pol alpha primase associated budding yeast replisome. Consensus refinement containing clear density for the Pri2-CTD and Pol1 exo/cat domains.

EMDB-16320:
Pol-alpha primase associated replisome binned consensus refinement in the absence of Ctf4, 60 nucleotide 5'-flap DNA fork

EMDB-16322:
Pol alpha-primase associated replisome unbinned consensus refinement in the absence of Ctf4, 60 nucleotide 5'-flap DNA fork

EMDB-16323:
Un-binned consensus refinement of Pol alpha-primase associated with the replisome only via the Pri2:Mcm5ZnF interface, 60 nucleotide 5'-flap DNA fork

EMDB-16885:
Pol12:Pol1CTD local refinement

EMDB-15351:
Pol alpha local refinement. Human replisome bound by Pol Alpha, engaged on a fork DNA substrate containing a 60 nt lagging strand.

EMDB-15356:
TIMELESS/TIPIN local refinement. Human replisome bound by Pol Alpha engaged on fork DNA with a 60 nt lagging strand.

EMDB-15303:
S. cerevisiae pol alpha bound to the core replisome engaged with a fork DNA substrate containing a 60 nucleotide lagging strand - unbinned.

EMDB-15304:
Csm3/Tof1 local refinement - pol alpha bound replisome

EMDB-15305:
C-tier local refinement, pol alpha - replisome complex. Locally filtered

EMDB-15306:
Pol12, PolA1 and Pri2 N-terminal domain local refinement. Pol alpha - replisome complex.

EMDB-15310:
Ctf4 - GINS - Cdc45 local refinement. Pol alpha - replisome complex.

EMDB-15340:
MCM C-tier local refinement. Human replisome bound by pol alpha, engaged on fork DNA with 60 nt lagging strand.

EMDB-15341:
Human replisome bound by pol alpha, engaged on fork DNA containing a 60 nt lagging strand.

EMDB-15342:
AND-1, CDC45, GINS local refinement. Human replisome bound by pol alpha - engaged on a 60 nt lagging strand DNA fork substrate.

EMDB-15349:
Human replisome bound by Pol Alpha, locally filtered. Strong PRIM1 density. Engaged on a fork DNA substrate containing a 60 nt lagging strand.

EMDB-13495:
Cryo-EM reconstruction of the S. cerevisiae replisome-SCF(Dia2) complex, bound to dsDNA (conformation I) - full complex (unsharpened map)

EMDB-13496:
Cryo-EM reconstruction of the S. cerevisiae replisome-SCF(Dia2) complex, bound to dsDNA (conformation I) - full complex (sharpened map)

EMDB-13497:
Cryo-EM reconstruction of the S. cerevisiae replisome-SCF(Dia2) complex, bound to dsDNA (conformation I) - MCM N-tier region

EMDB-13498:
Cryo-EM reconstruction of the S. cerevisiae replisome-SCF(Dia2) complex, bound to dsDNA (conformation I) - MCM C-tier region

EMDB-13500:
Cryo-EM reconstruction of the S. cerevisiae replisome-SCF(Dia2) complex, bound to dsDNA (conformation II) - full complex (unsharpened map)

EMDB-13512:
Cryo-EM reconstruction of the S. cerevisiae replisome-SCF(Dia2) complex, bound to dsDNA (conformation II) - full complex (sharpened map)

EMDB-13513:
Cryo-EM reconstruction of the S. cerevisiae replisome-SCF(Dia2) complex, bound to dsDNA (conformation II) - MCM N-tier region

EMDB-13514:
Cryo-EM reconstruction of the S. cerevisiae replisome-SCF(Dia2) complex, bound to dsDNA (conformation II) - MCM C-tier region

EMDB-13515:
Cryo-EM reconstruction of the S. cerevisiae replisome-SCF(Dia2) complex, bound to dsDNA - region encompassing Dia2-Skp1

EMDB-13516:
Cryo-EM reconstruction of the S. cerevisiae replisome-SCF(Dia2) complex, bound to dsDNA - region encompassing Cdc45-GINS-Ctf4-Dpb2N

EMDB-13517:
Cryo-EM reconstruction of the S. cerevisiae replisome-SCF(Dia2) complex, bound to dsDNA - region encompassing Pol2-Dpb2-Mcm5 WH

EMDB-13518:
Cryo-EM reconstruction of the S. cerevisiae replisome-SCF(Dia2) complex, bound to dsDNA, enriched for particles containing Csm3-Tof1

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