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Showing 1 - 50 of 200 items for author: y. & yu

PDB-5yhq:
Cryo-EM Structure of CVA6 VLP
Method: single particle / : Chen J, Zhang C, Huang Z, Cong Y

PDB-6b7n:
Cryo-electron microscopy structure of porcine delta coronavirus spike protein in the pre-fusion state
Method: single particle / : Shang J, Zheng Y, Yang Y, Liu C, Geng Q, Tai W, Du L, Zhou Y, Zhang W, Li F

PDB-5nd2:
Microtubule-bound MKLP2 motor domain in the presence of ADP
Method: single particle / : Atherton J, Yu IM, Cook A, Muretta JM, Joseph AP, Major J, Sourigues Y, Clause J, Topf M, Rosenfeld SS, Houdusse A, Moores CA

PDB-5nd3:
Microtubule-bound MKLP2 motor domain in the with no nucleotide
Method: single particle / : Atherton J, Yu IM, Cook A, Muretta JM, Joseph AP, Major J, Sourigues Y, Clause J, Topf M, Rosenfeld SS, Houdusse A, Moores CA

PDB-5nd4:
Microtubule-bound MKLP2 motor domain in the presence of ADP.AlFx
Method: single particle / : Atherton J, Yu IM, Cook A, Muretta JM, Joseph AP, Major J, Sourigues Y, Clause J, Topf M, Rosenfeld SS, Houdusse A, Moores CA

PDB-5nd7:
Microtubule-bound MKLP2 motor domain in the presence of AMPPNP
Method: single particle / : Atherton J, Yu IM, Cook A, Muretta JM, Joseph AP, Major J, Sourigues Y, Clause J, Topf M, Rosenfeld SS, Houdusse A, Moores CA

PDB-5xwy:
Electron cryo-microscopy structure of LbuCas13a-crRNA binary complex
Method: single particle / : Zhang X, Wang Y, Ma J, Liu L, Li X, Li Z, You L, Wang J, Wang M

PDB-5y3r:
Cryo-EM structure of Human DNA-PK Holoenzyme
Method: single particle / : Yin X, Liu M, Tian Y, Wang J, Xu Y

PDB-5vgz:
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
Method: single particle / : Lu Y, Wu J, Dong Y, Chen S, Sun S, Ma YB, Ouyang Q, Finley D, Kirschner MW, Mao Y

PDB-5vhf:
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
Method: single particle / : Lu Y, Wu J, Dong Y, Chen S, Sun S, Ma YB, Ouyang Q, Finley D, Kirschner MW, Mao Y

PDB-5vhh:
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
Method: single particle / : Lu Y, Wu J, Dong Y, Chen S, Sun S, Ma YB, Ouyang Q, Finley D, Kirschner MW, Mao Y

PDB-5vhi:
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
Method: single particle / : Lu Y, Wu J, Dong Y, Chen S, Sun S, Ma YB, Ouyang Q, Finley D, Kirschner MW, Mao Y

PDB-5vhj:
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
Method: single particle / : Lu Y, Wu J, Dong Y, Chen S, Sun S, Ma YB, Ouyang Q, Finley D, Kirschner MW, Mao Y

PDB-5vhm:
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
Method: single particle / : Lu Y, Wu J, Dong Y, Chen S, Sun S, Ma YB, Ouyang Q, Finley D, Kirschner MW, Mao Y

PDB-5vhn:
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
Method: single particle / : Lu Y, Wu J, Dong Y, Chen S, Sun S, Ma YB, Ouyang Q, Finley D, Kirschner MW, Mao Y

PDB-5vho:
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
Method: single particle / : Lu Y, Wu J, Dong Y, Chen S, Sun S, Ma YB, Ouyang Q, Finley D, Kirschner MW, Mao Y

PDB-5vhp:
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
Method: single particle / : Lu Y, Wu J, Dong Y, Chen S, Sun S, Ma YB, Ouyang Q, Finley D, Kirschner MW, Mao Y

PDB-5vhq:
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
Method: single particle / : Lu Y, Wu J, Dong Y, Chen S, Sun S, Ma YB, Ouyang Q, Finley D, Kirschner MW, Mao Y

PDB-5vhr:
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
Method: single particle / : Lu Y, Wu J, Dong Y, Chen S, Sun S, Ma YB, Ouyang Q, Finley D, Kirschner MW, Mao Y

PDB-5vhs:
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
Method: single particle / : Lu Y, Wu J, Dong Y, Chen S, Sun S, Ma YB, Ouyang Q, Finley D, Kirschner MW, Mao Y

PDB-5w65:
RNA polymerase I Initial Transcribing Complex State 2
Method: single particle / : Han Y, He Y

PDB-5uzb:
Cryo-EM structure of the MAL TIR domain filament
Method: helical / : Ve T, Vajjhala PR, Hedger A, Croll T, DiMaio F, Horsefield S, Yu X, Lavrencic P, Hassan Z, Morgan GP, Mansell A, Mobli M, O'Carrol A, Chauvin B, Gambin Y, Sierecki E, Landsberg MJ, Stacey KJ, Egelman EH, Kobe B

PDB-5w5y:
RNA polymerase I Initial Transcribing Complex
Method: single particle / : Han Y, He Y

PDB-5w64:
RNA Polymerase I Initial Transcribing Complex State 1
Method: single particle / : Han Y, He Y

PDB-5w66:
RNA polymerase I Initial Transcribing Complex State 3
Method: single particle / : Han Y, He Y

PDB-5ms1:
Cowpea mosaic virus top component (CPMV-T) - naturally occurring empty particles
Method: single particle / : Hesketh EL, Meshcheriakova Y, Thompson RF, Lomonossoff GP, Ranson NA

PDB-5msh:
Cowpea mosaic virus top component (CPMV-T) - naturally occurring empty particles
Method: single particle / : Hesketh EL, Meshcheriakova Y, Thompson RF, Lomonossoff GP, Ranson NA

PDB-5w1r:
Cryo-EM structure of DNAPKcs
Method: single particle / : Sharif H, Li Y, Wu H

PDB-5vot:
Structure of a Protein Complex
Method: single particle / : Chen S, Zhao Y, Wang YS, Shekhar M, Tajkhorshid E, Gouaux E

PDB-5vou:
Structure of a Protein Complex
Method: single particle / : Chen S, Zhao Y, Wang YS, Shekhar M, Tajkhorshid E, Gouaux E

PDB-5vov:
Structure of a Protein Complex
Method: single particle / : Zhao Y, Chen S, Wang YS, Shekhar M, Tajkhorshid E, Gouaux E

PDB-5w3e:
CryoEM structure of rhinovirus B14 in complex with C5 Fab (33 degrees Celsius, molar ratio 1:3, full particle)
Method: single particle / : Liu Y, Dong Y, Rossmann MG

PDB-5w3l:
CryoEM structure of rhinovirus B14 in complex with C5 Fab (4 degrees Celsius, molar ratio 1:3, full particle)
Method: single particle / : Liu Y, Dong Y, Rossmann MG

PDB-5w3m:
CryoEM structure of rhinovirus B14 in complex with C5 Fab (33 degrees Celsius, molar ratio 1:1, full particle)
Method: single particle / : Liu Y, Dong Y, Rossmann MG

PDB-5w3o:
CryoEM structure of rhinovirus B14 in complex with C5 Fab (33 degrees Celsius, molar ratio 1:3, empty particle)
Method: single particle / : Liu Y, Dong Y, Rossmann MG

PDB-5nd8:
Hibernating ribosome from Staphylococcus aureus (Unrotated state)
Method: single particle / : Khusainov I, Vicens Q, Ayupov R, Usachev K, Myasnikov A, Simonetti A, Validov S, Kieffer B, Yusupova G, Yusupov M, Hashem Y

PDB-5nd9:
Hibernating ribosome from Staphylococcus aureus (Rotated state)
Method: single particle / : Khusainov I, Vicens Q, Ayupov R, Usachev K, Myasnikov A, Simonetti A, Validov S, Kieffer B, Yusupova G, Yusupov M, Hashem Y

PDB-5vkq:
Structure of a mechanotransduction ion channel Drosophila NOMPC in nanodisc
Method: single particle / : Jin P, Bulkley D, Guo Y, Zhang W, Guo Z, Huynh W, Wu S, Meltzer S, Chen T, Jan LY, Jan YN, Cheng Y

PDB-5no3:
RsgA-GDPNP bound to the 30S ribosomal subunit (RsgA assembly intermediate without uS3)
Method: single particle / : Lopez-Alonso JP, Kaminishi T, Kikuchi T, Hirata Y, Iturrioz I, Dhimole N, Schedlbauer A, Hase Y, Goto S, Kurita D, Muto A, Zhou S, Naoe C, Mills DJ, Gil-Carton D, Takemoto C, Himeno H, Fucini P, Connell SR

PDB-5no4:
RsgA-GDPNP bound to the 30S ribosomal subunit (RsgA assembly intermediate with uS3)
Method: single particle / : Lopez-Alonso JP, Kaminishi T, Kikuchi T, Hirata Y, Iturrioz I, Dhimole N, Schedlbauer A, Hase Y, Goto S, Kurita D, Muto A, Zhou S, Naoe C, Mills DJ, Gil-Carton D, Takemoto C, Himeno H, Fucini P, Connell SR

PDB-5ujz:
CryoEM structure of an influenza virus receptor-binding site antibody-antigen interface - Class 1
Method: single particle / : Liu Y, Pan J, Caradonna T, Jenni S, Raymond DD, Schmidt AG, Harrison SC, Grigorieff N

PDB-5uk0:
CryoEM structure of an influenza virus receptor-binding site antibody-antigen interface - Class 2
Method: single particle / : Liu Y, Pan J, Caradonna T, Jenni S, Raymond DD, Schmidt AG, Harrison SC, Grigorieff N

PDB-5uk1:
CryoEM structure of an influenza virus receptor-binding site antibody-antigen interface - Class 3
Method: single particle / : Liu Y, Pan J, Caradonna T, Jenni S, Raymond DD, Schmidt AG, Harrison SC, Grigorieff N

PDB-5uk2:
CryoEM structure of an influenza virus receptor-binding site antibody-antigen interface - Class 4
Method: single particle / : Liu Y, Pan J, Caradonna T, Jenni S, Raymond DD, Schmidt AG, Harrison SC, Grigorieff N

PDB-5nco:
Quaternary complex between SRP, SR, and SecYEG bound to the translating ribosome
Method: single particle / : Jomaa A, Hwang Fu Y, Boerhinger D, Leibundgut M, Shan So, Ban N

PDB-5no2:
RsgA-GDPNP bound to the 30S ribosomal subunit (RsgA assembly intermediate)
Method: single particle / : Lopez-Alonso JP, Kaminishi T, Kikuchi T, Hirata Y, Iturrioz I, Dhimole N, Schedlbauer A, Hase Y, Goto S, Kurita D, Muto A, Zhou S, Naoe C, Mills DJ, Gil-Carton D, Takemoto C, Himeno H, Fucini P, Connell SR

PDB-5x58:
Prefusion structure of SARS-CoV spike glycoprotein, conformation 1
Method: single particle / : Yuan Y, Cao D, Zhang Y, Ma J, Qi J, Wang Q, Lu G, Wu Y, Yan J, Shi Y, Zhang X, Gao GF

PDB-5x59:
Prefusion structure of MERS-CoV spike glycoprotein, three-fold symmetry
Method: single particle / : Yuan Y, Cao D, Zhang Y, Ma J, Qi J, Wang Q, Lu G, Wu Y, Yan J, Shi Y, Zhang X, Gao GF

PDB-5x5b:
Prefusion structure of SARS-CoV spike glycoprotein, conformation 2
Method: single particle / : Yuan Y, Cao D, Zhang Y, Ma J, Qi J, Wang Q, Lu G, Wu Y, Yan J, Shi Y, Zhang X, Gao GF

PDB-5x5c:
Prefusion structure of MERS-CoV spike glycoprotein, conformation 1
Method: single particle / : Yuan Y, Cao D, Zhang Y, Ma J, Qi J, Wang Q, Lu G, Wu Y, Yan J, Shi Y, Zhang X, Gao GF

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Oct 4, 2017. Three pioneers of this field were awarded Nobel Prize in Chemistry 2017

Three pioneers of this field were awarded Nobel Prize in Chemistry 2017

  • Jacques Dubochet (University of Lausanne, Switzerland) is a pioneer of ice-embedding method of EM specimen (as known as cryo-EM), Most of 3DEM structures in EMDB and PDB are obtained using his method.
  • Joachim Frank (Columbia University, New York, USA) is a pioneer of single particle reconstruction, which is the most used reconstruction method for 3DEM structures in EMDB and EM entries in PDB. And also, he is a develper of Spider, which is one of the most famous software in this field, and is used for some EM Navigor data (e.g. map projection/slice images).
  • Richard Henderson (MRC Laboratory of Molecular Biology, Cambridge, UK) was determined the first biomolecule structure by EM. The first EM entry in PDB, PDB-1brd is determinedby him.

External links: The 2017 Nobel Prize in Chemistry - Press Release

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