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Showing all 45 items for (author: taunton & j)

EMDB-46597:
Human Sec61 complex inhibited by KZR-261
Method: single particle / : Park E, Wang L

PDB-9d6l:
Human Sec61 complex inhibited by KZR-261
Method: single particle / : Park E, Wang L

EMDB-52520:
Pre-clinical characterization of novel multi-client inhibitors of Sec61 with broad anti-tumor activity
Method: single particle / : Shahid R, Paavilainen VO

PDB-9hz5:
Pre-clinical characterization of novel multi-client inhibitors of Sec61 with broad anti-tumor activity
Method: single particle / : Shahid R, Paavilainen VO

EMDB-46598:
Human-yeast chimeric Sec complex bound to KZR-261 inhibitor
Method: single particle / : Park E, Wang L

EMDB-40344:
Terminating ribosome with SRI-41315
Method: single particle / : Yip MCJ, Coelho JPL, Oltion K, Tauton J, Shao S

EMDB-40345:
terminating rabbit ribosome with SRI-41315 (focused on ABCE1)
Method: single particle / : Yip MCJ, Coelho JPL, Oltion K, Tauton J, Shao S

PDB-8scb:
Terminating ribosome with SRI-41315
Method: single particle / : Yip MCJ, Coelho JPL, Oltion K, Tauton J, Shao S

EMDB-29757:
mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)
Method: single particle / : Holm M, Natchiar KS, Rundlet EJ, Myasnikov AG, Altman RB, Blanchard SC

EMDB-29758:
mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state)
Method: single particle / : Holm M, Natchiar KS, Rundlet EJ, Myasnikov AG, Altman RB, Blanchard SC

EMDB-29759:
mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state)
Method: single particle / : Holm M, Natchiar KS, Rundlet EJ, Myasnikov AG, Altman RB, Blanchard SC

EMDB-29760:
mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state)
Method: single particle / : Holm M, Natchiar KS, Rundlet EJ, Myasnikov AG, Altman RB, Blanchard SC

EMDB-29766:
mRNA decoding in human is kinetically and structurally distinct from bacteria (60S Focus refined map)
Method: single particle / : Holm M, Natchiar KS, Rundlet EJ, Myasnikov AG, Altman RB, Blanchard SC

EMDB-29768:
mRNA decoding in human is kinetically and structurally distinct from bacteria (40S Focus refined map)
Method: single particle / : Holm M, Natchiar KS, Rundlet EJ, Myasnikov AG, Altman RB, Blanchard SC

EMDB-29771:
mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)
Method: single particle / : Holm M, Natchiar KS, Rundlet EJ, Myasnikov AG, Altman RB, Blanchard SC

EMDB-29782:
mRNA decoding in human is kinetically and structurally distinct from bacteria (80S consensus refined structure)
Method: single particle / : Holm M, Natchiar KS, Rundlet EJ, Myasnikov AG, Altman RB, Blanchard SC

EMDB-40205:
mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)
Method: single particle / : Holm M, Natchiar KS, Rundlet EJ, Myasnikov AG, Watson ZL, Altman RB, Blanchard SC

PDB-8g5y:
mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)
Method: single particle / : Holm M, Natchiar KS, Rundlet EJ, Myasnikov AG, Altman RB, Blanchard SC

PDB-8g5z:
mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state)
Method: single particle / : Holm M, Natchiar KS, Rundlet EJ, Myasnikov AG, Altman RB, Blanchard SC

PDB-8g60:
mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state)
Method: single particle / : Holm M, Natchiar KS, Rundlet EJ, Myasnikov AG, Altman RB, Blanchard SC

PDB-8g61:
mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state)
Method: single particle / : Holm M, Natchiar KS, Rundlet EJ, Myasnikov AG, Altman RB, Blanchard SC

PDB-8g6j:
mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)
Method: single particle / : Holm M, Natchiar KS, Rundlet EJ, Myasnikov AG, Altman RB, Blanchard SC

PDB-8glp:
mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)
Method: single particle / : Holm M, Natchiar KS, Rundlet EJ, Myasnikov AG, Watson ZL, Altman RB, Blanchard SC

EMDB-14776:
Signal peptide mimicry primes Sec61 for client-selective inhibition
Method: single particle / : Rehan S, Paavilainen O V

PDB-7zl3:
Signal peptide mimicry primes Sec61 for client-selective inhibition
Method: single particle / : Rehan S, Paavilainen O V

EMDB-27732:
eEF1A(GDP)aa-tRNA stalled on the rabbit 80S ribosome by ternatin-4
Method: single particle / : Brown A, Shao S, Rundlet EJ, Juette MF, Carelli JD, Taunton J, Blanchard SC

EMDB-27691:
eEF1A(GDP)aa-tRNA stalled on the human 80S ribosome by didemnin B
Method: single particle / : Rundlet EJ, Juette MF, Blanchard SC, Ferguson A, Taunton J, Carelli JD

EMDB-27694:
eEF1A(GDP)aa-tRNA stalled on the human 80S ribosome by ternatin-4
Method: single particle / : Rundlet EJ, Ferguson A, Juette MF, Carelli JD, Taunton J, Blanchard SC

EMDB-4129:
Structure of the mammalian ribosome with P- and E-site tRNAs and an unoccupied A site
Method: single particle / : Shao S, Murray J, Brown A, Taunton J, Ramakrishnan V, Hegde RS

EMDB-4130:
Structure of the mammalian ribosomal elongation complex with aminoacyl-tRNA, eEF1A, and didemnin B
Method: single particle / : Shao S, Murray J

EMDB-4131:
Structure of the mammalian ribosomal termination complex with eRF1 and eRF3.
Method: single particle / : Shao S, Murray J

EMDB-4132:
Structure of the mammalian ribosomal termination complex with accommodated eRF1
Method: single particle / : Shao S, Murray J

EMDB-4133:
Structure of the mammalian ribosomal termination complex with accommodated eRF1(AAQ) and ABCE1.
Method: single particle / : Shao S, Murray J

EMDB-4134:
Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a truncated mRNA.
Method: single particle / : Shao S, Murray J

EMDB-4135:
Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a UGA stop codon.
Method: single particle / : Shao S, Murray J

EMDB-4136:
Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a polyadenylated mRNA.
Method: single particle / : Shao S, Murray J

EMDB-4137:
Structure of the mammalian rescue complex with Pelota and Hbs1l (combined)
Method: single particle / : Shao S, Murray J

PDB-5lzs:
Structure of the mammalian ribosomal elongation complex with aminoacyl-tRNA, eEF1A, and didemnin B
Method: single particle / : Shao S, Murray J, Brown A, Taunton J, Ramakrishnan V, Hegde RS

PDB-5lzt:
Structure of the mammalian ribosomal termination complex with eRF1 and eRF3.
Method: single particle / : Shao S, Murray J, Brown A, Taunton J, Ramakrishnan V, Hegde RS

PDB-5lzu:
Structure of the mammalian ribosomal termination complex with accommodated eRF1
Method: single particle / : Shao S, Murray J, Brown A, Taunton J, Ramakrishnan V, Hegde RS

PDB-5lzv:
Structure of the mammalian ribosomal termination complex with accommodated eRF1(AAQ) and ABCE1.
Method: single particle / : Shao S, Murray J, Brown A, Taunton J, Ramakrishnan V, Hegde RS

PDB-5lzw:
Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a truncated mRNA.
Method: single particle / : Shao S, Murray J, Brown A, Taunton J, Ramakrishnan V, Hegde RS

PDB-5lzx:
Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a UGA stop codon.
Method: single particle / : Shao S, Murray J, Brown A, Taunton J, Ramakrishnan V, Hegde RS

PDB-5lzy:
Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a polyadenylated mRNA.
Method: single particle / : Shao S, Murray J, Brown A, Taunton J, Ramakrishnan V, Hegde RS

PDB-5lzz:
Structure of the mammalian rescue complex with Pelota and Hbs1l (combined)
Method: single particle / : Shao S, Murray J, Brown A, Taunton J, Ramakrishnan V, Hegde RS

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New format data for meta-information of EMDB entries

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Oct 5, 2021. Nobel Prize for mechanically activated and temperature-gated ion channels

Nobel Prize for mechanically activated and temperature-gated ion channels

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External links:The Nobel Prize in Physiology or Medicine 2021 - NobelPrize.org / Structure data by Ardem Patapoutian / Structure data by David Julius

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