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Showing 1 - 50 of 58 items for author: s. & wang

PDB-5y0a:
Cryo-EM structure of zika virus complexed with Fab of ZKA190 at pH 8.0 and 37 celsius degree
Method: single particle / : Wang JQ, Lok SM

PDB-5xs4:
Structure of Coxsackievirus A6 (CVA6) virus A-particle
Method: single particle / : Zheng QB, He MZ, Xu LF, Yu H, Li SW, Cheng T

PDB-5xs5:
Structure of Coxsackievirus A6 (CVA6) virus procapsid particle
Method: single particle / : Zheng QB, He MZ, Xu LF, Yu H, Cheng T, Li SW

PDB-5xs7:
Structure of Coxsackievirus A6 (CVA6) virus A-particle in complex with the neutralizing antibody fragment 1D5
Method: single particle / : Zheng QB, He MZ, Xu LF, Yu H, Li SW, Cheng T

PDB-5xmi:
Cryo-EM Structure of the ATP-bound VPS4 mutant-E233Q hexamer (masked)
Method: single particle / : Sun S, Li L, Yang F, Wang X, Fan F, Li X, Wang H, Sui S

PDB-5xmk:
Cryo-EM structure of the ATP-bound Vps4 mutant-E233Q complex with Vta1 (masked)
Method: single particle / : Sun S, Li L, Yang F, Wang X, Fan F, Li X, Wang H, Sui S

PDB-5vot:
Structure of a Protein Complex
Method: single particle / : Chen S, Zhao Y, Wang YS, Shekhar M, Tajkhorshid E, Gouaux E

PDB-5vou:
Structure of a Protein Complex
Method: single particle / : Chen S, Zhao Y, Wang YS, Shekhar M, Tajkhorshid E, Gouaux E

PDB-5vov:
Structure of a Protein Complex
Method: single particle / : Zhao Y, Chen S, Wang YS, Shekhar M, Tajkhorshid E, Gouaux E

PDB-5nco:
Quaternary complex between SRP, SR, and SecYEG bound to the translating ribosome
Method: single particle / : Jomaa A, Hwang Fu Y, Boerhinger D, Leibundgut M, Shan So, Ban N

PDB-5wsn:
Structure of Japanese encephalitis virus
Method: single particle / : Wang X, Zhu L, Li S, Yuan S, Qin C, Fry EE, Stuart ID, Rao Z

PDB-5h3o:
Structure of a eukaryotic cyclic nucleotide-gated channel
Method: single particle / : Li M, Zhou X, Wang S, Michailidis I, Gong Y, Su D, Li H, Li X, Yang J

PDB-5wte:
Cryo-EM structure for Hepatitis A virus full particle
Method: single particle / : Wang X, Zhu L, Dang M, Hu Z, Gao Q, Yuan S, Sun Y, Zhang B, Ren J, Walter TS, Wang J, Fry EE, Stuart DI, Rao Z

PDB-5wtf:
Cryo-EM structure for Hepatitis A virus empty particle
Method: single particle / : Wang X, Zhu L, Dang M, Hu Z, Gao Q, Yuan S, Sun Y, Zhang B, Ren J, Walter TS, Wang J, Fry EE, Stuart DI, Rao Z

PDB-5wth:
Cryo-EM structure for Hepatitis A virus complexed with FAB
Method: single particle / : Wang X, Zhu L, Dang M, Hu Z, Gao Q, Yuan S, Sun Y, Zhang B, Ren J, Walter TS, Wang J, Fry EE, Stuart DI, Rao Z

PDB-5gzr:
Zika virus E protein complexed with a neutralizing antibody Z23-Fab
Method: single particle / : Gao GG, Shi Y, Peng R, Liu S

PDB-5fwp:
Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex
Method: single particle / : Verba KA, Wang RYR, Arakawa A, Liu Y, Yokoyama S, Agard DA

PDB-5gka:
cryo-EM structure of human Aichi virus
Method: single particle / : Zhu L, Wang XX, Ren JS, Tuthill TJ, Fry EE, Rao ZH, Stuart DI

PDB-5fwk:
Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex
Method: single particle / : Verba KA, Wang RYR, Arakawa A, Liu Y, Yokoyama S, Agard DA

PDB-5fwl:
Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex
Method: single particle / : Verba KA, Wang RYR, Arakawa A, Liu Y, Yokoyama S, Agard DA

PDB-5fwm:
Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex
Method: single particle / : Verba KA, Wang RYR, Arakawa A, Liu Y, Yokoyama S, Agard DA

PDB-5g06:
Cryo-EM structure of yeast cytoplasmic exosome
Method: single particle / : Liu JJ, Niu CY, Wu Y, Tan D, Wang Y, Ye MD, Liu Y, Zhao WW, Zhou K, Liu QS, Dai JB, Yang XR, Dong MQ, Huang N, Wang HW

PDB-5jb1:
Pseudo-atomic structure of Human Papillomavirus Type 59 L1 Virus-like Particle
Method: single particle / : Li ZH, Yan XD, Yu H, Zheng QB, Gu Y, Li SW

PDB-5g2x:
Structure a of Group II Intron Complexed with its Reverse Transcriptase
Method: single particle / : Qu G, Kaushal PS, Wang J, Shigematsu H, Piazza CL, Agrawal RK, Belfort M, Wang HW

PDB-5g2y:
Structure a of Group II Intron Complexed with its Reverse Transcriptase
Method: single particle / : Qu G, Kaushal PS, Wang J, Shigematsu H, Piazza CL, Agrawal RK, Belfort M, Wang HW

PDB-5i08:
Prefusion structure of a human coronavirus spike protein
Method: single particle / : Kirchdoerfer RN, Cottrell CA, Wang N, Pallesen J, Yassine HM, Turner HL, Corbett KS, Graham BS, McLellan JS, Ward AB

PDB-3jb4:
Structure of Ljungan virus: insight into picornavirus packaging
Method: single particle / : Zhu L, Wang XX, Ren JS, Porta C, Wenham H, Ekstrom JO, Panjwani A, Knowles NJ, Kotecha A, Siebert A, Lindberg M, Fry EE, Rao ZH, Tuthill TJ, Stuart DI

PDB-3jbl:
Cryo-EM Structure of the Activated NAIP2/NLRC4 Inflammasome Reveals Nucleated Polymerization
Method: single particle / : Zhang L, Chen S, Ruan J, Wu J, Tong AB, Yin Q, Li Y, David L, Lu A, Wang WL, Marks C, Ouyang Q, Zhang X, Mao Y, Wu H

PDB-3jav:
Structure of full-length IP3R1 channel in the apo-state determined by single particle cryo-EM
Method: single particle / : Fan G, Baker ML, Wang Z, Baker MR, Sinyagovskiy PA, Chiu W, Ludtke SJ, Serysheva II

PDB-3j9j:
Structure of the capsaicin receptor, TRPV1, determined by single particle electron cryo-microscopy
Method: single particle / : Wang RY-R, Barad BA, Fraser JS, DiMaio F

PDB-5a7x:
negative stain EM of BG505 SOSIP.664 in complex with sCD4, 17b, and 8ANC195
Method: single particle / : Scharf L, Wang H, Gao H, Chen S, McDowall A, Bjorkman P

PDB-5a8h:
cryo-ET subtomogram averaging of BG505 SOSIP.664 in complex with sCD4, 17b, and 8ANC195
Method: electron tomography / : Scharf L, Wang H, Gao H, Chen S, McDowall A, Bjorkman P

PDB-4uif:
Cryo-EM structure of Dengue virus serotype 2 in complex with antigen- binding fragments of human antibody 2D22
Method: single particle / : Fibriansah G, Ibarra KD, Ng TS, Smith SA, Tan JL, Lim XN, Ooi JSG, Kostyuchenko VA, Wang J, de Silva AM, Harris E, Crowe Junior JE, Lok SM

PDB-4uih:
Cryo-EM structure of Dengue virus serotype 2 strain New Guinea-C complexed with human antibody 2D22 Fab at 37 degree C. The Fab molecules were added to the virus before 37 degree C incubation.
Method: single particle / : Fibriansah G, Ibarra KD, Ng TS, Smith SA, Tan JL, Lim XN, Ooi JSG, Kostyuchenko VA, Wang J, deSilva AM, Harris E, Crowe JE, Lok SM

PDB-5a1z:
Cryo-EM structure of Dengue virus serotype 2 strain PVP94-07 complexed with human antibody 2D22 Fab at 37 degrees C
Method: single particle / : Fibriansah G, Ibarra KD, Ng TS, Smith SA, Tan JL, Lim XN, Ooi JSG, Kostyuchenko VA, Wang J, de Silva AM, Harris E, Crowe Jr JE, Lok SM

PDB-3j9g:
Atomic model of the VipA/VipB, the type six secretion system contractile sheath of Vibrio cholerae from cryo-EM
Method: helical / : Kudryashev M, Wang RY-R, Brackmann M, Scherer S, Maier T, Baker D, DiMaio F, Stahlberg H, Egelman EH, Basler M

PDB-3j9k:
Structure of Dark apoptosome in complex with Dronc CARD domain
Method: single particle / : Pang Y, Bai X, Yan C, Hao Q, Chen Z, Wang J, Scheres SHW, Shi Y

PDB-3j9l:
Structure of Dark apoptosome from Drosophila melanogaster
Method: single particle / : Pang Y, Bai X, Yan C, Hao Q, Chen Z, Wang J, Scheres SHW, Shi Y

PDB-3j9b:
Electron cryo-microscopy of an RNA polymerase
Method: single particle / : Chang SH, Sun DP, Liang HH, Wang J, Li J, Guo L, Wang XL, Guan CC, Boruah BM, Yuan LM, Feng F, Yang MR, Wojdyla J, Wang JW, Wang MT, Wang HW, Liu YF

PDB-3j7l:
Full virus map of brome mosaic virus
Method: single particle / : Wang Z, Hryc C, Bammes B, Afonine PV, Jakana J, Chen DH, Liu X, Baker ML, Kao C, Ludtke SJ, Schmid MF, Adams PD, Chiu W

PDB-3j7m:
Virus model of brome mosaic virus (first half data set)
Method: single particle / : Wang Z, Hryc C, Bammes B, Afonine PV, Jakana J, Chen DH, Liu X, Baker ML, Kao C, Ludtke SJ, Schmid MF, Adams PD, Chiu W

PDB-3j7n:
Virus model of brome mosaic virus (second half data set)
Method: single particle / : Wang Z, Hryc C, Bammes B, Afonine PV, Jakana J, Chen DH, Liu X, Baker ML, Kao C, Ludtke SJ, Schmid MF, Adams PD, Chiu W

PDB-4csu:
Cryo-EM structures of the 50S ribosome subunit bound with ObgE
Method: single particle / : Feng B, Mandava CS, Guo Q, Wang J, Cao W, Li N, Zhang Y, Zhang Y, Wang Z, Wu J, Sanyal S, Lei J, Gao N

PDB-4c2i:
Cryo-EM structure of Dengue virus serotype 1 complexed with Fab fragments of human antibody 1F4
Method: single particle / : Fibriansah G, Tan JL, de Alwis R, Smith SA, Ng TS, Kostyuchenko VA, Ibarra KD, Harris E, de Silva A, Crowe Junior JE, Lok SM

PDB-2m5k:
Atomic-resolution structure of a doublet cross-beta amyloid fibril
Method: single particle / : Fitzpatrick AWP, Debelouchina GT, Bayro MJ, Clare DK, Caporini MA, Bajaj VS, Jaroniec CP, Wang L, Ladizhansky V, Muller S, MacPhee CE, Waudby CA, Mott HR, de Simone A, Knowles TPJ, Saibil HR, Vendruscolo M, Orlova EV, Griffin RG, Dobson CM

PDB-2m5m:
Atomic-resolution structure of a triplet cross-beta amyloid fibril
Method: single particle / : Fitzpatrick AWP, Debelouchina GT, Bayro MJ, Clare DK, Caporini MA, Bajaj VS, Jaroniec CP, Wang L, Ladizhansky V, Muller S, MacPhee CE, Waudby CA, Mott HR, de Simone A, Knowles TPJ, Saibil HR, Vendruscolo M, Orlova EV, Griffin RG, Dobson CM

PDB-3zpk:
Atomic-resolution structure of a quadruplet cross-beta amyloid fibril
Method: single particle / : Fitzpatrick AwP, Debelouchina GT, Bayro MJ, Clare DK, Caporini MA, Bajaj VS, Jaroniec CP, Wang L, Ladizhansky V, Muller SA, MacPhee CE, Waudby CA, Mott HR, de Simone A, Knowles TPJ, Saibil HR, Vendruscolo M, Orlova EV, Griffin RG, Dobson CM

PDB-4bs1:
MuB is an AAAplus ATPase that forms helical filaments to control target selection for DNA transposition
Method: helical / : Mizuno N, Dramicanin M, Mizuuchi M, Adam J, Wang Y, Han YW, Yang W, Steven AC, Mizuuchi K, Ramon-Maiques S

PDB-4bt0:
MuB is an AAAplus ATPase that forms helical filaments to control target selection for DNA transposition
Method: single particle / : Mizuno N, Dramicanin M, Mizuuchi M, Adam J, Wang Y, Han YW, Yang W, Steven AC, Mizuuchi K, Ramon-Maiques S

PDB-4bt1:
MuB is an AAAplus ATPase that forms helical filaments to control target selection for DNA transposition
Method: single particle / : Mizuno N, Dramicanin M, Mizuuchi M, Adam J, Wang Y, Han YW, Yang W, Steven AC, Mizuuchi K, Ramon-Maiques S

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Oct 4, 2017. Three pioneers of this field were awarded Nobel Prize in Chemistry 2017

Three pioneers of this field were awarded Nobel Prize in Chemistry 2017

  • Jacques Dubochet (University of Lausanne, Switzerland) is a pioneer of ice-embedding method of EM specimen (as known as cryo-EM), Most of 3DEM structures in EMDB and PDB are obtained using his method.
  • Joachim Frank (Columbia University, New York, USA) is a pioneer of single particle reconstruction, which is the most used reconstruction method for 3DEM structures in EMDB and EM entries in PDB. And also, he is a develper of Spider, which is one of the most famous software in this field, and is used for some EM Navigor data (e.g. map projection/slice images).
  • Richard Henderson (MRC Laboratory of Molecular Biology, Cambridge, UK) was determined the first biomolecule structure by EM. The first EM entry in PDB, PDB-1brd is determinedby him.

External links: The 2017 Nobel Prize in Chemistry - Press Release

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