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Showing 1 - 50 of 299 items for (author: johnson & hr)

EMDB-49972: 
CryoEM structure of M. mazei topoisomerase VI(A-E342Q)-minicircle DNA complex in cleavage state
Method: single particle / : Richman DE, Wendorff TJ, Rashid F, Beck C, Yan Q, Johnson HR, Eckerty RA, Fogg JM, Baker ML, Zechiedrich L, Berger JM

EMDB-70206: 
CryoEM structure of M. mazei topoisomerase VI(A-E342Q)-minicircle DNA complex in asymmetric state
Method: single particle / : Richman DE, Berger JM

EMDB-70232: 
CryoEM structure of M. mazei topoisomerase VI-minicircle DNA complex
Method: single particle / : Richman DE, Wendorff TJ, Rashid F, Beck C, Yan Q, Johnson HR, Eckerty RA, Fogg JM, Baker ML, Zechiedrich L, Berger JM

EMDB-70239: 
CryoEM structure of M. mazei topoisomerase VI-minicircle DNA complex in partially unfolded transducer state
Method: single particle / : Richman DE, Wendorff TJ, Rashid F, Beck C, Yan Q, Johnson HR, Eckerty RA, Fogg JM, Baker ML, Zechiedrich L, Berger JM

EMDB-70259: 
CryoEM structure of M. mazei topoisomerase VI-minicircle DNA complex in asymmetric state
Method: single particle / : Richman DE, Berger JM

EMDB-72725: 
Cryo-EM structure of ternary complex BCL6-CRBN-DDB1 with BMS-986458 (local refined), a potent and selective BCL6 ligand directed degrader (LDD)
Method: single particle / : Zhu J, Fang W, Pagarigan B

PDB-9ya9: 
Cryo-EM structure of ternary complex BCL6-CRBN-DDB1 with BMS-986458 (local refined), a potent and selective BCL6 ligand directed degrader (LDD)
Method: single particle / : Zhu J, Fang W, Pagarigan B

EMDB-53353: 
Structure of Oceanobacillus iheyensis group II intron domains D1-D6
Method: single particle / : Jadhav SS, Nigro M, Marcia M

PDB-9qtj: 
Structure of Oceanobacillus iheyensis group II intron domains D1-D6
Method: single particle / : Jadhav SS, Nigro M, Marcia M

EMDB-72086: 
Cryo-EM structure of ternary complex BCL6-CRBN-DDB1 with BCL6-760 (LDD, local refined)
Method: single particle / : Zhu J, Fang W, Pagarigan B

PDB-9q03: 
Cryo-EM structure of ternary complex BCL6-CRBN-DDB1 with BCL6-760 (LDD, local refined)
Method: single particle / : Zhu J, Fang W, Pagarigan B

EMDB-71531: 
Angiopoietin-2 in complex with engineered conformationally rigid Fab 5A12.6DS, used for comparison with Fab 5A12.WT
Method: single particle / : Kung J, Johnson MC, Tegunov D, Jao CC, Wu P, Oh A, Lin M, Daria JM, Koth CM, Arthur CP, Rohou A, Sudhamsu J

EMDB-71532: 
Angiopoietin-2 in complex with Fab 5A12.WT, used for comparison with Fab 5A12.6DS
Method: single particle / : Kung J, Johnson MC, Tegunov D, Jao CC, Wu P, Oh A, Lin M, Daria JM, Koth CM, Arthur CP, Rohou A, Sudhamsu J

EMDB-72160: 
Cryo-EM structure of ternary complex Ikaros-ZF2:CC-885:CRBN:DDB1 (molecular glue degrader)
Method: single particle / : Zhu J, Pagarigan BE, Tran ET

PDB-9q2d: 
Cryo-EM structure of ternary complex Ikaros-ZF2:CC-885:CRBN:DDB1 (molecular glue degrader)
Method: single particle / : Zhu J, Pagarigan BE, Tran ET

EMDB-46597: 
Human Sec61 complex inhibited by KZR-261
Method: single particle / : Park E, Wang L

EMDB-52520: 
Pre-clinical characterization of novel multi-client inhibitors of Sec61 with broad anti-tumor activity
Method: single particle / : Shahid R, Paavilainen VO

PDB-9hz5: 
Pre-clinical characterization of novel multi-client inhibitors of Sec61 with broad anti-tumor activity
Method: single particle / : Shahid R, Paavilainen VO

EMDB-46598: 
Human-yeast chimeric Sec complex bound to KZR-261 inhibitor
Method: single particle / : Park E, Wang L

EMDB-52210: 
TRPML1 in complex with compound 2
Method: single particle / : Reeks J, Mahajan P, Clark M, Cowan SR, Di Daniel E, Earl CP, Fisher S, Holvey RS, Jackson SM, Lloyd-Evans E, Morgillo CM, Mortenson PN, O'Reilly M, Richardson CJ, Schopf P, Tams DM, Waller-Evans H, Ward SE, Whibley S, Williams PA, Johnson CN

EMDB-52211: 
TRPML1 in complex with compound 5
Method: single particle / : Reeks J, Mahajan P, Clark M, Cowan SR, Di Daniel E, Earl CP, Fisher S, Holvey RS, Jackson SM, Lloyd-Evans E, Morgillo CM, Mortenson PN, O'Reilly M, Richardson CJ, Schopf P, Tams DM, Waller-Evans H, Ward SE, Whibley S, Williams PA, Johnson CN

EMDB-52242: 
TRPML1 in complex with compound 1a
Method: single particle / : Reeks J, Mahajan P, Clark M, Cowan SR, Di Daniel E, Earl CP, Fisher S, Holvey RS, Jackson SM, Lloyd-Evans E, Morgillo CM, Mortenson PN, O'Reilly M, Richardson CJ, Schopf P, Tams DM, Waller-Evans H, Ward SE, Whibley S, Williams PA, Johnson CN

EMDB-52243: 
TRPML1 in complex with compound 3
Method: single particle / : Reeks J, Mahajan P, Clark M, Cowan SR, Di Daniel E, Earl CP, Fisher S, Holvey RS, Jackson SM, Lloyd-Evans E, Morgillo CM, Mortenson PN, O'Reilly M, Richardson CJ, Schopf P, Tams DM, Waller-Evans H, Ward SE, Whibley S, Williams PA, Johnson CN

EMDB-52245: 
TRPML1 in complex with compound 4a
Method: single particle / : Reeks J, Mahajan P, Clark M, Cowan SR, Di Daniel E, Earl CP, Fisher S, Holvey RS, Jackson SM, Lloyd-Evans E, Morgillo CM, Mortenson PN, O'Reilly M, Richardson CJ, Schopf P, Tams DM, Waller-Evans H, Ward SE, Whibley S, Williams PA, Johnson CN

EMDB-52246: 
TRPML1 in complex with compound 8
Method: single particle / : Reeks J, Mahajan P, Clark M, Cowan SR, Di Daniel E, Earl CP, Fisher S, Holvey RS, Jackson SM, Lloyd-Evans E, Morgillo CM, Mortenson PN, O'Reilly M, Richardson CJ, Schopf P, Tams DM, Waller-Evans H, Ward SE, Whibley S, Williams PA, Johnson CN

EMDB-52248: 
TRPML1 in complex with compound 9a
Method: single particle / : Reeks J, Mahajan P, Clark M, Cowan SR, Di Daniel E, Earl CP, Fisher S, Holvey RS, Jackson SM, Lloyd-Evans E, Morgillo CM, Mortenson PN, O'Reilly M, Richardson CJ, Schopf P, Tams DM, Waller-Evans H, Ward SE, Whibley S, Williams PA, Johnson CN

EMDB-52249: 
TRPML1 in complex with compound 10
Method: single particle / : Reeks J, Mahajan P, Clark M, Cowan SR, Di Daniel E, Earl CP, Fisher S, Holvey RS, Jackson SM, Lloyd-Evans E, Morgillo CM, Mortenson PN, O'Reilly M, Richardson CJ, Schopf P, Tams DM, Waller-Evans H, Ward SE, Whibley S, Williams PA, Johnson CN

EMDB-52250: 
TRPML1 in complex with compound 11
Method: single particle / : Reeks J, Mahajan P, Clark M, Cowan SR, Di Daniel E, Earl CP, Fisher S, Holvey RS, Jackson SM, Lloyd-Evans E, Morgillo CM, Mortenson PN, O'Reilly M, Richardson CJ, Schopf P, Tams DM, Waller-Evans H, Ward SE, Whibley S, Williams PA, Johnson CN

EMDB-52251: 
TRPML1 in complex with compound 13
Method: single particle / : Reeks J, Mahajan P, Clark M, Cowan SR, Di Daniel E, Earl CP, Fisher S, Holvey RS, Jackson SM, Lloyd-Evans E, Morgillo CM, Mortenson PN, O'Reilly M, Richardson CJ, Schopf P, Tams DM, Waller-Evans H, Ward SE, Whibley S, Williams PA, Johnson CN

PDB-9hj6: 
TRPML1 in complex with compound 2
Method: single particle / : Reeks J, Mahajan P, Clark M, Cowan SR, Di Daniel E, Earl CP, Fisher S, Holvey RS, Jackson SM, Lloyd-Evans E, Morgillo CM, Mortenson PN, O'Reilly M, Richardson CJ, Schopf P, Tams DM, Waller-Evans H, Ward SE, Whibley S, Williams PA, Johnson CN

PDB-9hj8: 
TRPML1 in complex with compound 5
Method: single particle / : Reeks J, Mahajan P, Clark M, Cowan SR, Di Daniel E, Earl CP, Fisher S, Holvey RS, Jackson SM, Lloyd-Evans E, Morgillo CM, Mortenson PN, O'Reilly M, Richardson CJ, Schopf P, Tams DM, Waller-Evans H, Ward SE, Whibley S, Williams PA, Johnson CN

PDB-9hl3: 
TRPML1 in complex with compound 1a
Method: single particle / : Reeks J, Mahajan P, Clark M, Cowan SR, Di Daniel E, Earl CP, Fisher S, Holvey RS, Jackson SM, Lloyd-Evans E, Morgillo CM, Mortenson PN, O'Reilly M, Richardson CJ, Schopf P, Tams DM, Waller-Evans H, Ward SE, Whibley S, Williams PA, Johnson CN

PDB-9hl4: 
TRPML1 in complex with compound 3
Method: single particle / : Reeks J, Mahajan P, Clark M, Cowan SR, Di Daniel E, Earl CP, Fisher S, Holvey RS, Jackson SM, Lloyd-Evans E, Morgillo CM, Mortenson PN, O'Reilly M, Richardson CJ, Schopf P, Tams DM, Waller-Evans H, Ward SE, Whibley S, Williams PA, Johnson CN

PDB-9hl6: 
TRPML1 in complex with compound 4a
Method: single particle / : Reeks J, Mahajan P, Clark M, Cowan SR, Di Daniel E, Earl CP, Fisher S, Holvey RS, Jackson SM, Lloyd-Evans E, Morgillo CM, Mortenson PN, O'Reilly M, Richardson CJ, Schopf P, Tams DM, Waller-Evans H, Ward SE, Whibley S, Williams PA, Johnson CN

PDB-9hl8: 
TRPML1 in complex with compound 8
Method: single particle / : Reeks J, Mahajan P, Clark M, Cowan SR, Di Daniel E, Earl CP, Fisher S, Holvey RS, Jackson SM, Lloyd-Evans E, Morgillo CM, Mortenson PN, O'Reilly M, Richardson CJ, Schopf P, Tams DM, Waller-Evans H, Ward SE, Whibley S, Williams PA, Johnson CN

PDB-9hla: 
TRPML1 in complex with compound 9a
Method: single particle / : Reeks J, Mahajan P, Clark M, Cowan SR, Di Daniel E, Earl CP, Fisher S, Holvey RS, Jackson SM, Lloyd-Evans E, Morgillo CM, Mortenson PN, O'Reilly M, Richardson CJ, Schopf P, Tams DM, Waller-Evans H, Ward SE, Whibley S, Williams PA, Johnson CN

PDB-9hlb: 
TRPML1 in complex with compound 10
Method: single particle / : Reeks J, Mahajan P, Clark M, Cowan SR, Di Daniel E, Earl CP, Fisher S, Holvey RS, Jackson SM, Lloyd-Evans E, Morgillo CM, Mortenson PN, O'Reilly M, Richardson CJ, Schopf P, Tams DM, Waller-Evans H, Ward SE, Whibley S, Williams PA, Johnson CN

PDB-9hlc: 
TRPML1 in complex with compound 11
Method: single particle / : Reeks J, Mahajan P, Clark M, Cowan SR, Di Daniel E, Earl CP, Fisher S, Holvey RS, Jackson SM, Lloyd-Evans E, Morgillo CM, Mortenson PN, O'Reilly M, Richardson CJ, Schopf P, Tams DM, Waller-Evans H, Ward SE, Whibley S, Williams PA, Johnson CN

PDB-9hld: 
TRPML1 in complex with compound 13
Method: single particle / : Reeks J, Mahajan P, Clark M, Cowan SR, Di Daniel E, Earl CP, Fisher S, Holvey RS, Jackson SM, Lloyd-Evans E, Morgillo CM, Mortenson PN, O'Reilly M, Richardson CJ, Schopf P, Tams DM, Waller-Evans H, Ward SE, Whibley S, Williams PA, Johnson CN

EMDB-44760: 
Human Amylin1 Receptor in complex with Gs and cagrilintide
Method: single particle / : Cao J, Belousoff MJ, Johnson RM, Sexton PM, Wootten DL

EMDB-44796: 
Human Amylin2 Receptor in Complex with Gs and Cagrilintide
Method: single particle / : Cao J, Belousoff MJ, Wootten DL, Sexton PM, Johnson RM

EMDB-44904: 
Human calcitonin Receptor in complex with Gs and cagrilintide in the bypass conformation
Method: single particle / : Cao J, Belousoff MJ, Johnson RM, Sexton PM, Wootten DL

EMDB-44905: 
Human calcitonin Receptor in complex with Gs and cagrilintide in the bypass conformation (repeat)
Method: single particle / : Cao J, Belousoff MJ, Johnson RM, Sexton PM, Wootten DL

EMDB-44906: 
Human calcitonin Receptor in complex with Gs and cagrilintide in the CT-like conformation
Method: single particle / : Cao J, Belousoff MJ, Johnson RM, Sexton PM, Wootten DL

PDB-9bp3: 
Human Amylin1 Receptor in complex with Gs and cagrilintide
Method: single particle / : Cao J, Belousoff MJ, Johnson RM, Sexton PM, Wootten DL

PDB-9bq3: 
Human Amylin2 Receptor in Complex with Gs and Cagrilintide
Method: single particle / : Cao J, Belousoff MJ, Wootten DL, Sexton PM, Johnson RM

PDB-9bub: 
Human calcitonin Receptor in complex with Gs and cagrilintide in the bypass conformation
Method: single particle / : Cao J, Belousoff MJ, Johnson RM, Sexton PM, Wootten DL

PDB-9buc: 
Human calcitonin Receptor in complex with Gs and cagrilintide in the bypass conformation (repeat)
Method: single particle / : Cao J, Belousoff MJ, Johnson RM, Sexton PM, Wootten DL

PDB-9bud: 
Human calcitonin Receptor in complex with Gs and cagrilintide in the CT-like conformation
Method: single particle / : Cao J, Belousoff MJ, Johnson RM, Sexton PM, Wootten DL
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