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TitleStructural dynamics insights into principles underlying the increased fitness of newly engineered and broadly potent AAV capsids
Journal, issue, pagesTo Be Published
Publish dateNov 24, 2025 (structure data deposition date)
AuthorsJohnson ME / Ozturk BE / Tugwell TH / Lambros M / Janowitz H / Sedorovitz M / Flohr K / Campello L / Hartung JE / Hogle B ...Johnson ME / Ozturk BE / Tugwell TH / Lambros M / Janowitz H / Sedorovitz M / Flohr K / Campello L / Hartung JE / Hogle B / Gillespie M / Schriever H / Aweidah H / Koester J / Clausen I / Seeber S / Revelant F / Schreurs R / Koechl F / Sieving PA / Sahel JA / Stauffer WR / Peixoto RT / Fauser S / Lin R / Conway J / Da Silva S / Krol J / Betegon M / Byrne LC
External linksSearch PubMed
MethodsEM (single particle)
Resolution1.9 Å
Structure data

74043

9zcw

EMDB-74043, PDB-9zcw:
Cryo-EM structure of the engineered vector AAV2.ATX002
Method: EM (single particle) / Resolution: 1.9 Å

Source
  • adeno-associated virus 2
KeywordsVIRUS / Adeno-Associated Virus / AAV / Engineered AAV / AAV2

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