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Showing 1 - 50 of 287 items for (author: hunt & j)

EMDB-72497: 
V-shaped (channel-formed), ATP-bound, VX809-bound conformation of wild-type human CFTR (composite map from PHENIX based on consensus and local refinement maps from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Baranwal J, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

PDB-9y4t: 
V-shaped (channel-formed), ATP-bound, VX809-bound conformation of wild-type human CFTR (composite map from PHENIX based on consensus and local refinement maps from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Baranwal J, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-72356: 
V-shaped (channel-formed), ATP-bound, VX809-bound conformation of wild-type human CFTR (sharpened AHD1 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Baranwal J, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-72403: 
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (Composite map from PHENIX)
Method: single particle / : Hunt JF, Paige AS, Govaerts C, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Overtus M, Rich Z

EMDB-72491: 
V-shaped (channel-formed), ATP-bound, VX809-bound conformation of wild-type human CFTR (sharpened WalkerB2 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Baranwal J, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-72492: 
V-shaped (channel-formed), ATP-bound, VX809-bound conformation of wild-type human CFTR (sharpened AHD2 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Baranwal J, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-72493: 
V-shaped (channel-formed), ATP-bound, VX809-bound conformation of wild-type human CFTR (sharpened CORE2 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Baranwal J, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-72494: 
V-shaped (channel-formed), ATP-bound, VX809-bound conformation of wild-type human CFTR (sharpened WalkerB1 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z, Baranwal J

EMDB-72495: 
V-shaped (channel-formed), ATP-bound, VX809-bound conformation of wild-type human CFTR (sharpened CORE1 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Baranwal J, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-72496: 
V-shaped (channel-formed), ATP-bound, VX809-bound conformation of wild-type human CFTR ( Consensus map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Baranwal J, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

PDB-9y1q: 
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (Composite map from PHENIX)
Method: single particle / : Hunt JF, Paige AS, Govaerts C

EMDB-54696: 
Chlorophyll synthase in complex with the LHC-like protein HliD, apo state
Method: single particle / : Shvarev D, Hitchcock A, Sobotka R

EMDB-54697: 
Chlorophyll synthase in complex with the LHC-like protein HliD, GGPP-bound state
Method: single particle / : Shvarev D, Hitchcock A, Sobotka R

EMDB-54698: 
Chlorophyll synthase in complex with the LHC-like protein HliD, apo state, consensus map
Method: single particle / : Shvarev D, Hitchcock A, Sobotka R

EMDB-54699: 
Chlorophyll synthase in complex with the LHC-like protein HliD, GGPP-bound state, consensus map
Method: single particle / : Shvarev D, Hitchcock A, Sobotka R

EMDB-54700: 
Chlorophyll synthase in complex with the LHC-like protein HliD, ChlGx1-HliDx2 complex, apo sample
Method: single particle / : Shvarev D, Hitchcock A, Sobotka R

EMDB-54701: 
Chlorophyll synthase in complex with the LHC-like protein HliD, ChlGx1-HliDx2 complex, GGPP sample
Method: single particle / : Shvarev D, Hitchcock A, Sobotka R

EMDB-56052: 
Structure of human prothrombinase with prothrombin
Method: single particle / : Faille A, Ustok FI, Warren A, Huntingon JA

EMDB-56054: 
Structure of human prothrombinase with meizothrombin
Method: single particle / : Faille A, Ustok FI, Warren A, Huntingon JA

PDB-9tle: 
Structure of human prothrombinase with prothrombin
Method: single particle / : Faille A, Ustok FI, Warren A, Huntingon JA

PDB-9tlg: 
Structure of human prothrombinase with meizothrombin
Method: single particle / : Faille A, Ustok FI, Warren A, Huntingon JA

EMDB-71756: 
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened consensus map from cryoSPARC non-uniform refinement)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71757: 
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened AHD1 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71758: 
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened AHD2 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71759: 
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened CORE1 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71760: 
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened CORE2 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71761: 
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened WalkerB1 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71762: 
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened WalkerB2 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71763: 
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened NBD1 plus T2a local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71764: 
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened NBD2 plus T2a local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71765: 
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened T2a plus T2a local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71698: 
V-shaped (channel-formed), ATP-bound, VX809-bound, T2a-nanobody-bound conformation of wild-type human CFTR (sharpened AHD1 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71709: 
V-shaped (channel-formed), ATP-bound, VX809-bound, T2a-nanobody-bound conformation of wild-type human CFTR (sharpened AHD2 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71710: 
V-shaped (channel-formed), ATP-bound, VX809-bound, T2a-nanobody-bound conformation of wild-type human CFTR (sharpened CORE1 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71711: 
V-shaped (channel-formed), ATP-bound, VX809-bound, T2a-nanobody-bound conformation of wild-type human CFTR (sharpened CORE2 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71713: 
V-shaped (channel-formed), ATP-bound, VX809-bound, T2a-nanobody-bound conformation of wild-type human CFTR (sharpened WalkerB2 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71714: 
V-shaped (channel-formed), ATP-bound, VX809-bound, T2a-nanobody-bound conformation of wild-type human CFTR (sharpened T2a local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-73644: 
AI-generated RNA-guided nuclease TAM-bound state
Method: single particle / : Skopintsev P, Esain-Garcia I, Doudna J

EMDB-73645: 
AI-generated RNA-guided nuclease R-loop formed state
Method: single particle / : Skopintsev P, Esain-Garcia I, Doudna J

PDB-9yyg: 
AI-generated RNA-guided nuclease TAM-bound state
Method: single particle / : Skopintsev P, Esain-Garcia I, Doudna J

PDB-9yyh: 
AI-generated RNA-guided nuclease R-loop formed state
Method: single particle / : Skopintsev P, Esain-Garcia I, Doudna J

EMDB-53342: 
Low resolution cryo-EM map of activin A bound to B52 Fabs
Method: single particle / : Pyeatt GL, Hyvonen M, Maia de Oliveira T, Jin Y, Miller D, Hunt J, Hill CS

EMDB-74880: 
Dimer structure of Thlaspi arvense plastid biotin carboxylase
Method: single particle / : Madison HJ, Van Doren SR, Yokom AL

EMDB-74881: 
Tetramer structure of Thlaspi arvense plastid biotin carboxylase
Method: single particle / : Madison HJ, Van Doren SR, Yokom AL

PDB-9zvm: 
Dimer structure of Thlaspi arvense plastid biotin carboxylase
Method: single particle / : Madison HJ, Van Doren SR, Yokom AL

EMDB-74113: 
Competition for different elements of the nucleosome acidic patch yields distinct functional outcomes. VHH 1B2
Method: single particle / : Chakraborty U, Saccone EC, Becerra GC, Khan LF, Arslanovic N, Aguilar R, Gloor SL, Hunt SR, Folkwein HJ, Husby NL, Maier KE, Marunde MR, Schomburg NK, Vaidya A, Cowles MW, Venters BJ, Kassavetis G, Sun ZW, Kadonaga JT, Armache JP, Keogh MC, Tyler JK

EMDB-74114: 
Competition for different elements of the nucleosome acidic patch yields distinct functional outcomes. VHH 1G1
Method: single particle / : Chakraborty U, Saccone EC, Becerra GC, Khan LF, Arslanovic N, Aguilar R, Gloor SL, Hunt SR, Folkwein HJ, Husby NL, Maier KE, Marunde MR, Schomburg NK, Vaidya A, Cowles MW, Venters BJ, Kassavetis G, Sun ZW, Kadonaga JT, Armache JP, Keogh MC, Tyler JK

PDB-9zen: 
Competition for different elements of the nucleosome acidic patch yields distinct functional outcomes. VHH 1B2
Method: single particle / : Chakraborty U, Saccone EC, Becerra GC, Khan LF, Arslanovic N, Aguilar R, Gloor SL, Hunt SR, Folkwein HJ, Husby NL, Maier KE, Marunde MR, Schomburg NK, Vaidya A, Cowles MW, Venters BJ, Kassavetis G, Sun ZW, Kadonaga JT, Armache JP, Keogh MC, Tyler JK

PDB-9zeo: 
Competition for different elements of the nucleosome acidic patch yields distinct functional outcomes. VHH 1G1
Method: single particle / : Chakraborty U, Saccone EC, Becerra GC, Khan LF, Arslanovic N, Aguilar R, Gloor SL, Hunt SR, Folkwein HJ, Husby NL, Maier KE, Marunde MR, Schomburg NK, Vaidya A, Cowles MW, Venters BJ, Kassavetis G, Sun ZW, Kadonaga JT, Armache JP, Keogh MC, Tyler JK

EMDB-72725: 
Cryo-EM structure of ternary complex BCL6-CRBN-DDB1 with BMS-986458 (local refined), a potent and selective BCL6 ligand directed degrader (LDD)
Method: single particle / : Zhu J, Fang W, Pagarigan B
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