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TitleAI-generated RNA-guided nuclease TAM-bound state
Journal, issue, pagesTo Be Published
Publish dateOct 29, 2025 (structure data deposition date)
AuthorsSkopintsev P / Esain-Garcia I / Doudna J
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.8 Å
Structure data

73644

9yyg

EMDB-73644, PDB-9yyg:
AI-generated RNA-guided nuclease TAM-bound state
Method: EM (single particle) / Resolution: 2.8 Å

Source
  • synthetic construct (others)
  • deinococcus radiodurans (radioresistant)
KeywordsRNA BINDING PROTEIN / CRISPR / nuclease / AI / Evolution Scale Modeling / Inverse Folding / ESM-IF1 / TnpB / TAM / PAM / spacer / exonuclease / DNA binding protein-DNA complex / enzyme / ribonucleoprotein / RNA / RNA-guided nuclease / Cas12 / ISDra2 / ESM

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