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Showing 1 - 50 of 232 items for (author: case & da)

EMDB-70721: 
TMPRSS2 (S441A) bound to the HCoV-NL63 S2'region genetically fused to the HCoV-HKU1 RBD
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-70722: 
TMPRSS2 S441A in complex with the H1H7 Fab and anti-kappa light chain nanobody
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-73656: 
SARS-CoV-2 spike trimer in the early fusion intermediate conformation bound to the VN01H1 Fab (Fab local refinement)
Method: single particle / : Park YJ, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-73657: 
SARS-CoV-2 spike trimer in the early fusion intermediate conformation bound to the VN01H1 Fab (S2 local refinement)
Method: single particle / : Park YJ, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-73786: 
HCoV-NL63 S2' peptide bound to TMPRSS2 S441A (complexed with the H1H7 Fab and an anti-kappa-nanobody)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-73787: 
SARS-CoV-2 S2 trimer stabilized in the early fusion intermediate conformation by circular permutation and clamping by gp41 (E-FICs-v1)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-75233: 
SARS-CoV-2 spike trimer in the early fusion intermediate conformation bound to the VN01H1 Fab (global refinement)
Method: single particle / : Park YJ, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-75694: 
SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to the VN01H1 Fab (Fab local refinement)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-75695: 
SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to the VN01H1 Fab (S2 local refinement)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-75705: 
SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to C77G12 (Fab local refinement)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-75721: 
SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to the VN01H1 Fab
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-75722: 
SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to C77G12 (global refinement)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

PDB-11hk: 
SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to the VN01H1 Fab (Fab local refinement)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

PDB-11hl: 
SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to the VN01H1 Fab (S2 local refinement)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

PDB-11hw: 
SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to C77G12 (Fab local refinement)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

PDB-9opq: 
TMPRSS2 (S441A) bound to the HCoV-NL63 S2'region genetically fused to the HCoV-HKU1 RBD
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

PDB-9opr: 
TMPRSS2 S441A in complex with the H1H7 Fab and anti-kappa light chain nanobody
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

PDB-9yyu: 
SARS-CoV-2 spike trimer in the early fusion intermediate conformation bound to the VN01H1 Fab (Fab local refinement)
Method: single particle / : Park YJ, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

PDB-9yyv: 
SARS-CoV-2 spike trimer in the early fusion intermediate conformation bound to the VN01H1 Fab (S2 local refinement)
Method: single particle / : Park YJ, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

PDB-9z3j: 
HCoV-NL63 S2' peptide bound to TMPRSS2 S441A (complexed with the H1H7 Fab and an anti-kappa-nanobody)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

PDB-9z3k: 
SARS-CoV-2 S2 trimer stabilized in the early fusion intermediate conformation by circular permutation and clamping by gp41 (E-FICs-v1)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-76230: 
Structure of TMEM106B doublet from patient brain derived lysosomes
Method: subtomogram averaging / : Fernandez MF, Mosalaganti S

EMDB-76248: 
Structure of TMEM106B singlet from patient brain derived lysosomes
Method: subtomogram averaging / : Fernandez MF, Mosalaganti S

EMDB-75697: 
SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to C77G12 (S2 local refinement)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

PDB-11hn: 
SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to C77G12 (S2 local refinement)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-53950: 
SsCl at pH 6.5 - closed
Method: single particle / : Kleiz-Ferreira J, Brams M, Harrison PJ, Gallagher C, Nys M, Donze Y, Quigley A, Bertrand D, Ulens C

EMDB-53951: 
SsCl at pH 6.5 + IVM - Partially opened
Method: single particle / : Kleiz-Ferreira J, Brams M, Harrison PJ, Gallagher C, Nys M, Donze Y, Quigley A, Bertrand D, Ulens C

EMDB-53952: 
SsCl at pH 9 - Desensitized
Method: single particle / : Kleiz-Ferreira J, Brams M, Harrison PJ, Gallagher C, Nys M, Donze Y, Quigley A, Bertrand D, Ulens C

EMDB-53953: 
SsCl at pH 9 + IVM - Opened
Method: single particle / : Kleiz-Ferreira J, Brams M, Harrison PJ, Gallagher C, Nys M, Donze Y, Quigley A, Bertrand D, Ulens C

PDB-9rgm: 
SsCl at pH 6.5 - closed
Method: single particle / : Kleiz-Ferreira J, Brams M, Harrison PJ, Gallagher C, Nys M, Donze Y, Quigley A, Bertrand D, Ulens C

PDB-9rgn: 
SsCl at pH 6.5 + IVM - Partially opened
Method: single particle / : Kleiz-Ferreira J, Brams M, Harrison PJ, Gallagher C, Nys M, Donze Y, Quigley A, Bertrand D, Ulens C

PDB-9rgo: 
SsCl at pH 9 - Desensitized
Method: single particle / : Kleiz-Ferreira J, Brams M, Harrison PJ, Gallagher C, Nys M, Donze Y, Quigley A, Bertrand D, Ulens C

PDB-9rgp: 
SsCl at pH 9 + IVM - Opened
Method: single particle / : Kleiz-Ferreira J, Brams M, Harrison PJ, Gallagher C, Nys M, Donze Y, Quigley A, Bertrand D, Ulens C

EMDB-74981: 
The ER membrane protein complex acts as a chaperone to promote voltage-gated calcium channel assembly
Method: single particle / : Singal B, Biswal M, Pleiner T

PDB-9zz6: 
The ER membrane protein complex acts as a chaperone to promote voltage-gated calcium channel assembly
Method: single particle / : Singal B, Biswal M, Pleiner T

EMDB-45969: 
Local refinement of the SARS-CoV-2 BA.2.86 RBD in complex with TRI2-2 minibinder
Method: single particle / : Lee J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-45971: 
Local refinement of the SARS-CoV-2 BA.2.86 NTD
Method: single particle / : Lee J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-45972: 
SARS-CoV-2 BA.2.86 Spike trimer in complex with TRI2-2 minibinder
Method: single particle / : Lee J, Veesler D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)

PDB-9cwp: 
Local refinement of the SARS-CoV-2 BA.2.86 RBD in complex with TRI2-2 minibinder
Method: single particle / : Lee J, Veesler D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)

PDB-9cwq: 
Local refinement of the SARS-CoV-2 BA.2.86 NTD
Method: single particle / : Lee J, Veesler D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)

PDB-9cwr: 
SARS-CoV-2 BA.2.86 Spike trimer in complex with TRI2-2 minibinder
Method: single particle / : Lee J, Veesler D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)

EMDB-70458: 
Cryo-EM structure of human full-length XPO1 (unliganded)
Method: single particle / : Wing CE, Fung HYJ, Chook YM

EMDB-70459: 
Cryo-EM structure of human full-length XPO1 conjugated with selinexor
Method: single particle / : Wing CE, Fung HYJ, Chook YM

EMDB-70460: 
Cryo-EM structure of human exportin-1 conjugated with selinexor and bound to yeast RAN-GTP and human ASB8-ELOB/C
Method: single particle / : Wing CE, Fung HYJ, Chook YM

EMDB-70461: 
Cryo-EM structure of human exportin-1 conjugated with KPT-185 and bound to human ASB8-ELOB/C
Method: single particle / : Wing CE, Fung HYJ, Chook YM

EMDB-70462: 
Cryo-EM structure of human exportin-1 conjugated with selinexor and bound to human ASB8(R197A)-ELOB/C
Method: single particle / : Wing CE, Fung HYJ, Chook YM

EMDB-70463: 
Cryo-EM structure of human exportin-1 conjugated with KPT-127 and bound to human ASB8-ELOB/C
Method: single particle / : Wing CE, Fung HYJ, Chook YM

EMDB-70464: 
Cryo-EM structure of human exportin-1 conjugated with KPT-UTSW1 and bound to human ASB8-ELOB/C
Method: single particle / : Wing CE, Fung HYJ, Chook YM

PDB-9og9: 
Cryo-EM structure of human full-length XPO1 (unliganded)
Method: single particle / : Wing CE, Fung HYJ, Chook YM

PDB-9oga: 
Cryo-EM structure of human full-length XPO1 conjugated with selinexor
Method: single particle / : Wing CE, Fung HYJ, Chook YM
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