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2M37
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STRUCTURE OF LASSO PEPTIDE ASTEXIN-1
Descriptor:ASTEXIN-1
Authors:Zimmermann, M., Hegemann, J.D., Xie, X., Marahiel, M.A.
Deposit date:2013-01-14
Release date:2013-05-01
Method:SOLUTION NMR
Cite:The astexin-1 lasso peptides: biosynthesis, stability, and structural studies.
Chem.Biol., 20, 2013
2MLJ
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STRUCTURE OF LASSO PEPTIDE CAULONODIN V
Descriptor:Caulonodin V
Authors:Zimmermann, M., Hegemann, J.D., Xie, X., Marahiel, M.A.
Deposit date:2014-02-28
Release date:2015-01-14
Method:SOLUTION NMR
Cite:Characterization of caulonodin lasso peptides revealed unprecedented N-terminal residues and a precursor motif essential for peptide maturation
CHEM SCI, 5, 2014
3DXS
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CRYSTAL STRUCTURE OF A COPPER BINDING DOMAIN FROM HMA7, A P-TYPE ATPASE
Descriptor:Copper-transporting ATPase RAN1, ZINC ION, LITHIUM ION
Authors:Zimmermann, M., Xiao, Z., Clarke, O.B., Gulbis, J.M., Wedd, A.G.
Deposit date:2008-07-25
Release date:2009-08-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Metal binding affinities of Arabidopsis zinc and copper transporters: selectivities match the relative, but not the absolute, affinities of their amino-terminal domains.
Biochemistry, 48, 2009
5OGI
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COMPLEX OF A BINDING PROTEIN AND HUMAN ADENOVIRUS C 5 HEXON
Descriptor:Hexon protein, scFv of 9C12 antibody, SULFATE ION, ...
Authors:Schmid, M., Ernst, P., Honegger, A., Suomalainen, M., Zimmermann, M., Braun, L., Stauffer, S., Thom, C., Dreier, B., Eibauer, M., Kipar, A., Vogel, V., Greber, U.F., Medalia, O., Plueckthun, A.
Deposit date:2017-07-13
Release date:2018-02-07
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Adenoviral vector with shield and adapter increases tumor specificity and escapes liver and immune control.
Nat Commun, 9, 2018
6EQC
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CRYO-EM RECONSTRUCTION OF A COMPLEX OF A BINDING PROTEIN AND HUMAN ADENOVIRUS C5 HEXON
Descriptor:Hexon protein, scFv of 9C12 antibody
Authors:Schmid, M., Ernst, P., Honegger, A., Suomalainen, M., Zimmermann, M., Braun, L., Stauffer, S., Thom, C., Dreier, B., Eibauer, M., Kipar, A., Vogel, V., Greber, U.F., Medalia, O., Plueckthun, A.
Deposit date:2017-10-12
Release date:2018-02-07
Last modified:2018-02-14
Method:ELECTRON MICROSCOPY (7.4 Å)
Cite:Adenoviral vector with shield and adapter increases tumor specificity and escapes liver and immune control.
Nat Commun, 9, 2018
2MMT
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LASSO PEPTIDE-BASED INTEGRIN INHIBITOR: MICROCIN J25 VARIANT WITH RGDF SUBSTITUTION OF GLY12-ILE13-GLY14-THR15
Descriptor:Microcin J25 RGDF mutant
Authors:Hegemann, J.D., Zimmermann, M., Knappe, T.A., Xie, X., Marahiel, M.A.
Deposit date:2014-03-18
Release date:2014-07-02
Last modified:2014-07-23
Method:SOLUTION NMR
Cite:Rational improvement of the affinity and selectivity of integrin binding of grafted lasso peptides.
J.Med.Chem., 57, 2014
2L41
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NAB3 RRM - UCUU COMPLEX
Descriptor:RRM domain from Nuclear polyadenylated RNA-binding protein 3, RNA (5'-R(P*UP*CP*UP*U)-3')
Authors:Stefl, R., Pergoli, R., Hobor, F., Kubicek, K., Zimmermann, M., Pasulka, J., Hofr, C.
Deposit date:2010-09-28
Release date:2010-11-17
Last modified:2012-05-30
Method:SOLUTION NMR
Cite:Recognition of transcription termination signal by the nuclear polyadenylated RNA-binding (NAB) 3 protein
J.Biol.Chem., 286, 2011
2LX6
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STRUCTURE OF LASSO PEPTIDE CAULOSEGNIN I
Descriptor:Putative uncharacterized protein
Authors:Hegemann, J.D., Zimmermann, M., Xie, X., Marahiel, M.A.
Deposit date:2012-08-15
Release date:2012-12-26
Last modified:2013-01-23
Method:SOLUTION NMR
Cite:Caulosegnins I-III: A Highly Diverse Group of Lasso Peptides Derived from a Single Biosynthetic Gene Cluster.
J.Am.Chem.Soc., 135, 2013
2MFV
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STRUCTURE OF LASSO PEPTIDE XANTHOMONIN II
Descriptor:Xanthomonin II
Authors:Hegemann, J.D., Zimmermann, M., Harms, K., Xie, X., Marahiel, M.A.
Deposit date:2013-10-23
Release date:2014-10-29
Method:SOLUTION NMR
Cite:Xanthomonin I-III are Lasso Peptides Featuring Macrolactam Rings Consisting of Only Seven Amino Acids
To be Published
4NAG
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XANTHOMONINS I III ARE A NEW CLASS OF LASSO PEPTIDES FEATURINGA SEVEN-MEMBERED MACROLACTAM RING
Descriptor:Xanthomonin I, HEXANE-1,6-DIOL
Authors:Hegemann, J.D., Zimmermann, M., Zhu, S., Steuber, H., Harms, K., Xie, X., Marahiel, M.A.
Deposit date:2013-10-22
Release date:2014-04-30
Last modified:2014-05-21
Method:X-RAY DIFFRACTION (0.81 Å)
Cite:Xanthomonins I-III: A New Class of Lasso Peptides with a Seven-Residue Macrolactam Ring.
Angew.Chem.Int.Ed.Engl., 53, 2014
2KKH
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STRUCTURE OF THE ZINC BINDING DOMAIN OF THE ATPASE HMA4
Descriptor:Putative heavy metal transporter, ZINC ION
Authors:Zimmerman, M., Clarke, O., Gulbis, J.M., Keizer, D.W., Jarvis, R.S., Cobbett, C.S., Hinds, M.G., Xiao, Z., Wedd, A.G.
Deposit date:2009-06-20
Release date:2010-01-26
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Metal binding affinities of Arabidopsis zinc and copper transporters: selectivities match the relative, but not the absolute, affinities of their amino-terminal domains
Biochemistry, 48, 2009
2L2J
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SOLUTION NMR STRUCTURE OF THE LOWER PART OF THE R/G STEM LOOP RNA
Descriptor:RNA (42-MER)
Authors:Oberstrass, F.F., Allain, F.H.-T., Stefl, R.
Deposit date:2010-08-20
Release date:2010-10-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The Solution Structure of the ADAR2 dsRBM-RNA Complex Reveals a Sequence-Specific Readout of the Minor Groove.
Cell(Cambridge,Mass.), 143, 2010
2L2K
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SOLUTION NMR STRUCTURE OF THE R/G STEM LOOP RNA-ADAR2 DSRBM2 COMPLEX
Descriptor:Adenosine deaminase, RNA (42-MER)
Authors:Allain, F.H.-T., Oberstrass, F.C., Stefl, R.
Deposit date:2010-08-20
Release date:2010-10-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The Solution Structure of the ADAR2 dsRBM-RNA Complex Reveals a Sequence-Specific Readout of the Minor Groove.
Cell(Cambridge,Mass.), 143, 2010
2L3C
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SOLUTION STRUCTURE OF ADAR2 DSRBM1 BOUND TO LSL RNA
Descriptor:Double-stranded RNA-specific editase 1, RNA (34-MER)
Authors:Allain, F., Stefl, R., Oberstrass, F.
Deposit date:2010-09-12
Release date:2010-10-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The Solution Structure of the ADAR2 dsRBM-RNA Complex Reveals a Sequence-Specific Readout of the Minor Groove.
Cell(Cambridge,Mass.), 143, 2010
2L3J
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THE SOLUTION STRUCTURE OF THE ADAR2 DSRBM-RNA COMPLEX REVEALS A SEQUENCE-SPECIFIC READ OUT OF THE MINOR GROOVE
Descriptor:Double-stranded RNA-specific editase 1, RNA (71-MER)
Authors:Stefl, R., Oberstrass, F.C., Allain, F.H.-T.
Deposit date:2010-09-14
Release date:2010-10-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The Solution Structure of the ADAR2 dsRBM-RNA Complex Reveals a Sequence-Specific Readout of the Minor Groove.
Cell(Cambridge,Mass.), 143, 2010
4OBU
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RUMINOCOCCUS GNAVUS TRYPTOPHAN DECARBOXYLASE RUMGNA_01526 (APO)
Descriptor:Pyridoxal-dependent decarboxylase domain protein, PYRIDOXAL-5'-PHOSPHATE
Authors:Van Benschoten, A.H., Fraser, J.S.
Deposit date:2014-01-07
Release date:2014-10-29
Method:X-RAY DIFFRACTION (2.804 Å)
Cite:Discovery and Characterization of Gut Microbiota Decarboxylases that Can Produce the Neurotransmitter Tryptamine.
Cell Host Microbe, 16, 2014
4OBV
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RUMINOCOCCUS GNAVUS TRYPTOPHAN DECARBOXYLASE RUMGNA_01526 (ALPHA-FMT)
Descriptor:Pyridoxal-dependent decarboxylase domain protein, alpha-(fluoromethyl)-D-tryptophan, {5-hydroxy-4-[(1E)-4-(1H-indol-3-yl)-3-oxobut-1-en-1-yl]-6-methylpyridin-3-yl}methyl dihydrogen phosphate
Authors:Fraser, J.S., Van Benschoten, A.H.
Deposit date:2014-01-07
Release date:2014-10-29
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Discovery and Characterization of Gut Microbiota Decarboxylases that Can Produce the Neurotransmitter Tryptamine.
Cell Host Microbe, 16, 2014
3UVQ
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HUMAN P38 MAP KINASE IN COMPLEX WITH A DIBENZOSUBERONE DERIVATIVE
Descriptor:Mitogen-activated protein kinase 14, N-{5-[(7-{[(2R)-2,3-dihydroxypropyl]oxy}-5-oxo-10,11-dihydro-5H-dibenzo[a,d][7]annulen-2-yl)amino]-2-fluorophenyl}benzamide, B-OCTYLGLUCOSIDE
Authors:Mayer-Wrangowski, S.C., Richters, A., Gruetter, C., Rauh, D.
Deposit date:2011-11-30
Release date:2012-12-05
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Dibenzosuberones as p38 mitogen-activated protein kinase inhibitors with low ATP competitiveness and outstanding whole blood activity.
J.Med.Chem., 56, 2013