6EQC
Cryo-EM reconstruction of a complex of a binding protein and human adenovirus C5 hexon
Summary for 6EQC
Entry DOI | 10.2210/pdb6eqc/pdb |
Related | 5OGI |
EMDB information | 3821 |
Descriptor | Hexon protein, scFv of 9C12 antibody (2 entities in total) |
Functional Keywords | antibody, human adenovirus c5, gene therapy viral protein, viral protein |
Biological source | Mus musculus (House Mouse) More |
Cellular location | Virion : P04133 |
Total number of polymer chains | 6 |
Total formula weight | 405896.08 |
Authors | Schmid, M.,Ernst, P.,Honegger, A.,Suomalainen, M.,Zimmermann, M.,Braun, L.,Stauffer, S.,Thom, C.,Dreier, B.,Eibauer, M.,Kipar, A.,Vogel, V.,Greber, U.F.,Medalia, O.,Plueckthun, A. (deposition date: 2017-10-12, release date: 2018-02-07, Last modification date: 2018-02-14) |
Primary citation | Schmid, M.,Ernst, P.,Honegger, A.,Suomalainen, M.,Zimmermann, M.,Braun, L.,Stauffer, S.,Thom, C.,Dreier, B.,Eibauer, M.,Kipar, A.,Vogel, V.,Greber, U.F.,Medalia, O.,Pluckthun, A. Adenoviral vector with shield and adapter increases tumor specificity and escapes liver and immune control. Nat Commun, 9:450-450, 2018 Cited by PubMed: 29386504DOI: 10.1038/s41467-017-02707-6 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (7.4 Å) |
Structure validation
Download full validation report