Author results

1FRP
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CRYSTAL STRUCTURE OF FRUCTOSE-1,6-BISPHOSPHATASE COMPLEXED WITH FRUCTOSE-2,6-BISPHOSPHATE, AMP AND ZN2+ AT 2.0 ANGSTROMS RESOLUTION. ASPECTS OF SYNERGISM BETWEEN INHIBITORS
Descriptor:FRUCTOSE 1,6-BISPHOSPHATASE, FRUCTOSE-2,6-DIPHOSPHATE, ZINC ION, ...
Authors:Xue, Y., Huang, S., Liang, J.-Y., Zhang, Y., Lipscomb, W.N.
Deposit date:1994-08-26
Release date:1994-11-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of fructose-1,6-bisphosphatase complexed with fructose 2,6-bisphosphate, AMP, and Zn2+ at 2.0-A resolution: aspects of synergism between inhibitors.
Proc.Natl.Acad.Sci.USA, 91, 1994
3Q7G
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CRYSTAL STRUCTURE OF E2 DOMAIN OF HUMAN AMYLOID PRECURSOR-LIKE PROTEIN 1 IN COMPLEX WITH SOS (SUCROSE OCTASULFATE)
Descriptor:Amyloid-like protein 1, SUCROSE OCTASULFATE
Authors:Xue, Y., Ha, Y.
Deposit date:2011-01-04
Release date:2011-06-22
Last modified:2011-09-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of the E2 Domain of Amyloid Precursor Protein-like Protein 1 in Complex with Sucrose Octasulfate.
J.Biol.Chem., 286, 2011
3Q7L
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CRYSTAL STRUCTURE OF THE E2 DOMAIN OF AMYLOID PRECURSOR-LIKE PROTEIN 1
Descriptor:Amyloid-like protein 1, SULFATE ION
Authors:Xue, Y., Ha, Y.
Deposit date:2011-01-05
Release date:2011-06-29
Last modified:2011-09-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of the E2 Domain of Amyloid Precursor Protein-like Protein 1 in Complex with Sucrose Octasulfate.
J.Biol.Chem., 286, 2011
3UBB
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THE CRYSTAL STRUCTURE OF GLPG IN COMPLEX WITH A PHOSPHONOFLUORIDATE INHIBITOR
Descriptor:Rhomboid protease glpG, propan-2-yl hydrogen (S)-[(1R)-1-{[(benzyloxy)carbonyl]amino}ethyl]phosphonate
Authors:Xue, Y., Ha, Y.
Deposit date:2011-10-24
Release date:2012-06-13
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Conformational Change in Rhomboid Protease GlpG Induced by Inhibitor Binding to Its S' Subsites.
Biochemistry, 51, 2012
3QMK
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CRYSTAL STRUCTURE OF THE E2 DOMAIN OF APLP1 IN COMPLEX WITH HEPARIN HEXASACCHARIDE
Descriptor:Amyloid-like protein 1, 2-O-sulfo-alpha-L-idopyranuronic acid, N,O6-DISULFO-GLUCOSAMINE, ...
Authors:Xue, Y., Ha, Y.
Deposit date:2011-02-04
Release date:2011-10-12
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal structure of amyloid precursor-like protein 1 and heparin complex suggests a dual role of heparin in E2 dimerization.
Proc.Natl.Acad.Sci.USA, 108, 2011
3TXT
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CRYSTAL STRUCTURE OF GLPG IN COMPLEX WITH INHIBITOR DFP
Descriptor:Rhomboid protease glpG, DIISOPROPYL PHOSPHONATE
Authors:Xue, Y., Ha, Y.
Deposit date:2011-09-23
Release date:2011-12-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of rhomboid protease GlpG in complex with a mechanism-based inhibitor
To be Published
4BTJ
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TTBK1 IN COMPLEX WITH ATP
Descriptor:TAU-TUBULIN KINASE 1, ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, ...
Authors:Xue, Y., Wan, P., Hillertz, P., Schweikart, F., Zhao, Y., Wissler, L., Dekker, N.
Deposit date:2013-06-18
Release date:2013-09-25
Last modified:2017-03-29
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:X-Ray Structural Analysis of Tau-Tubulin Kinase 1 and its Interactions with Small Molecular Inhibitors.
Chemmedchem, 8, 2013
4BTK
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TTBK1 IN COMPLEX WITH INHIBITOR
Descriptor:TAU-TUBULIN KINASE 1, DIMETHYL SULFOXIDE, 4-[3-HYDROXYANILINO]-6,7-DIMETHOXYQUINAZOLINE
Authors:Xue, Y., Wan, P., Hillertz, P., Schweikart, F., Zhao, Y., Wissler, L., Dekker, N.
Deposit date:2013-06-18
Release date:2013-09-25
Last modified:2017-03-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-Ray Structural Analysis of Tau-Tubulin Kinase 1 and its Interactions with Small Molecular Inhibitors.
Chemmedchem, 8, 2013
4BTM
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TTBK1 IN COMPLEX WITH INHIBITOR
Descriptor:TAU-TUBULIN KINASE 1, SULFATE ION, methyl 2-bromo-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)benzoate, ...
Authors:Xue, Y., Wan, P., Hillertz, P., Schweikart, F., Zhao, Y., Wissler, L., Dekker, N.
Deposit date:2013-06-18
Release date:2013-09-25
Last modified:2017-03-29
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:X-Ray Structural Analysis of Tau-Tubulin Kinase 1 and its Interactions with Small Molecular Inhibitors.
Chemmedchem, 8, 2013
4H1D
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COCRYSTAL STRUCTURE OF GLPG AND DFP
Descriptor:Rhomboid protease GlpG, DIISOPROPYL PHOSPHONATE
Authors:Xue, Y., Ha, Y.
Deposit date:2012-09-10
Release date:2013-05-01
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2.8975 Å)
Cite:Large lateral movement of transmembrane helix s5 is not required for substrate access to the active site of rhomboid intramembrane protease.
J.Biol.Chem., 288, 2013
1A7C
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HUMAN PLASMINOGEN ACTIVATOR INHIBITOR TYPE-1 IN COMPLEX WITH A PENTAPEPTIDE
Descriptor:PLASMINOGEN ACTIVATOR INHIBITOR TYPE 1, PENTAPEPTIDE, RIBOSE(PYRANOSE FORM), ...
Authors:Xue, Y., Inghardt, T., Sjolin, L., Deinum, J.
Deposit date:1998-03-12
Release date:1999-03-23
Last modified:2012-02-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Interfering with the inhibitory mechanism of serpins: crystal structure of a complex formed between cleaved plasminogen activator inhibitor type 1 and a reactive-centre loop peptide
Structure, 6, 1998
1AG6
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PLASTOCYANIN FROM SPINACH
Descriptor:PLASTOCYANIN, COPPER (II) ION
Authors:Xue, Y., Okvist, M., Young, S.
Deposit date:1997-04-02
Release date:1998-10-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of spinach plastocyanin at 1.7 A resolution.
Protein Sci., 7, 1998
1BIC
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CRYSTALLOGRAPHIC ANALYSIS OF THR-200-> HIS HUMAN CARBONIC ANHYDRASE II AND ITS COMPLEX WITH THE SUBSTRATE, HCO3-
Descriptor:CARBONIC ANHYDRASE II, ZINC ION, BICARBONATE ION, ...
Authors:Xue, Y., Vidgren, J., Svensson, L.A., Liljas, A., Jonsson, B.-H., Lindskog, S.
Deposit date:1992-09-01
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystallographic analysis of Thr-200-->His human carbonic anhydrase II and its complex with the substrate, HCO3-.
Proteins, 15, 1993
1CAI
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STRUCTURAL ANALYSIS OF THE ZINC HYDROXIDE-THR 199-GLU 106 HYDROGEN BONDING NETWORK IN HUMAN CARBONIC ANHYDRASE II
Descriptor:CARBONIC ANHYDRASE II, ZINC ION, SULFATE ION
Authors:Xue, Y., Liljas, A., Jonsson, B.-H., Lindskog, S.
Deposit date:1992-09-17
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural analysis of the zinc hydroxide-Thr-199-Glu-106 hydrogen-bond network in human carbonic anhydrase II.
Proteins, 17, 1993
1CAJ
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STRUCTURAL ANALYSIS OF THE ZINC HYDROXIDE-THR 199-GLU 106 HYDROGEN BONDING NETWORK IN HUMAN CARBONIC ANHYDRASE II
Descriptor:CARBONIC ANHYDRASE II, ZINC ION, SULFATE ION
Authors:Xue, Y., Liljas, A., Jonsson, B.-H., Lindskog, S.
Deposit date:1992-09-17
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of the zinc hydroxide-Thr-199-Glu-106 hydrogen-bond network in human carbonic anhydrase II.
Proteins, 17, 1993
1CAK
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STRUCTURAL ANALYSIS OF THE ZINC HYDROXIDE-THR 199-GLU 106 HYDROGEN BONDING NETWORK IN HUMAN CARBONIC ANHYDRASE II
Descriptor:CARBONIC ANHYDRASE II, ZINC ION, SULFATE ION
Authors:Xue, Y., Liljas, A., Jonsson, B.-H., Lindskog, S.
Deposit date:1992-09-17
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of the zinc hydroxide-Thr-199-Glu-106 hydrogen-bond network in human carbonic anhydrase II.
Proteins, 17, 1993
1CAL
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STRUCTURAL ANALYSIS OF THE ZINC HYDROXIDE-THR 199-GLU 106 HYDROGEN BONDING NETWORK IN HUMAN CARBONIC ANHYDRASE II
Descriptor:CARBONIC ANHYDRASE II, ZINC ION
Authors:Xue, Y., Liljas, A., Jonsson, B.-H., Lindskog, S.
Deposit date:1992-09-17
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural analysis of the zinc hydroxide-Thr-199-Glu-106 hydrogen-bond network in human carbonic anhydrase II.
Proteins, 17, 1993
1CAM
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STRUCTURAL ANALYSIS OF THE ZINC HYDROXIDE-THR 199-GLU 106 HYDROGEN BONDING NETWORK IN HUMAN CARBONIC ANHYDRASE II
Descriptor:CARBONIC ANHYDRASE II, ZINC ION, BICARBONATE ION
Authors:Xue, Y., Liljas, A., Jonsson, B.-H., Lindskog, S.
Deposit date:1992-09-17
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural analysis of the zinc hydroxide-Thr-199-Glu-106 hydrogen-bond network in human carbonic anhydrase II.
Proteins, 17, 1993
1CSM
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THE CRYSTAL STRUCTURE OF ALLOSTERIC CHORISMATE MUTASE AT 2.2 ANGSTROMS RESOLUTION
Descriptor:CHORISMATE MUTASE, TRYPTOPHAN
Authors:Xue, Y., Lipscomb, W.N.
Deposit date:1994-08-22
Release date:1995-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structure of allosteric chorismate mutase at 2.2-A resolution.
Proc.Natl.Acad.Sci.USA, 91, 1994
2AFR
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THE CRYSTAL STRUCTURE OF PUTATIVE PRECORRIN ISOMERASE CBIC IN COBALAMIN BIOSYNTHESIS
Descriptor:cobalamin biosynthesis precorrin isomerase
Authors:Xue, Y., Wei, Z., Li, X.
Deposit date:2005-07-26
Release date:2006-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of putative precorrin isomerase CbiC in cobalamin biosynthesis
J.Struct.Biol., 153, 2006
2AFV
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THE CRYSTAL STRUCTURE OF PUTATIVE PRECORRIN ISOMERASE CBIC IN COBALAMIN BIOSYNTHESIS
Descriptor:cobalamin biosynthesis precorrin isomerase, CHLORIDE ION, HEXAETHYLENE GLYCOL, ...
Authors:Xue, Y., Wei, Z.
Deposit date:2005-07-26
Release date:2006-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The crystal structure of putative precorrin isomerase CbiC in cobalamin biosynthesis
J.Struct.Biol., 153, 2006
2O9I
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CRYSTAL STRUCTURE OF THE HUMAN PREGNANE X RECEPTOR LBD IN COMPLEX WITH AN SRC-1 COACTIVATOR PEPTIDE AND T0901317
Descriptor:Orphan nuclear receptor PXR, Nuclear Receptor Coactivator 1 isoform 3, N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE
Authors:Xue, Y., Redinbo, M.R.
Deposit date:2006-12-13
Release date:2007-01-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the PXR-T1317 complex provides a scaffold to examine the potential for receptor antagonism.
Bioorg.Med.Chem., 15, 2007
2VB2
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CRYSTAL STRUCTURE OF CU(I)CUSF
Descriptor:CATION EFFLUX SYSTEM PROTEIN CUSF, SULFATE ION, COPPER (II) ION
Authors:Xue, Y., Davis, A.V., Balakrishnan, G., Stasser, J.P., Staehlin, B.M., Focia, P., Spiro, T.G., Penner-Hahn, J.E., O'Halloran, T.V.
Deposit date:2007-09-06
Release date:2007-12-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Cu(I) Recognition Via Cation-Pi and Methionine Interactions in Cusf.
Nat.Chem.Biol., 4, 2008
2VB3
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CRYSTAL STRUCTURE OF AG(I)CUSF
Descriptor:CATION EFFLUX SYSTEM PROTEIN CUSF, SILVER ION
Authors:Xue, Y., Davis, A.V., Balakrishnan, G., Stasser, J.P., Staehlin, B.M., Focia, P., Spiro, T.G., Penner-Hahn, J.E., O'Halloran, T.V.
Deposit date:2007-09-06
Release date:2007-12-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Cu(I) Recognition Via Cation-Pi and Methionine Interactions in Cusf.
Nat.Chem.Biol., 4, 2008
4A5T
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STRUCTURAL BASIS FOR THE CONFORMATIONAL MODULATION
Descriptor:PLASMINOGEN, O-SIALIC ACID, BETA-D-GALACTOSE, ...
Authors:Xue, Y., Bodin, C., Olsson, K.
Deposit date:2011-10-28
Release date:2012-05-23
Last modified:2012-07-18
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Crystal Structure of the Native Plasminogen Reveals an Activation-Resistant Compact Conformation.
J. Thromb. Haemost., 10, 2012