4BTM

TTBK1 in complex with inhibitor

Summary for 4BTM

• Entry DOI: 10.2210/pdb4btm/pdb
• Related: 4BTJ 4BTK
• Descriptor: TAU-TUBULIN KINASE 1, SULFATE ION, methyl 2-bromo-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)benzoate, ... (6 entities in total)
• Functional Keywords: transferase, ligand complex, structure-kinetics relationship
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Cytoplasm : Q5TCY1
• Total number of polymer chains: 2
• Total formula weight: 78741.90

Authors

Xue, Y.,Wan, P.,Hillertz, P.,Schweikart, F.,Zhao, Y.,Wissler, L.,Dekker, N. (deposition date: 2013-06-18, release date: 2013-09-25, Last modification date: 2023-12-20)

• Primary citation: Xue, Y.,Wan, P.T.,Hillertz, P.,Schweikart, F.,Zhao, Y.,Wissler, L.,Dekker, N.; X-Ray Structural Analysis of Tau-Tubulin Kinase 1 and its Interactions with Small Molecular Inhibitors.; Chemmedchem, 8:1846-, 2013; PubMed: 24039150; DOI: 10.1002/CMDC.201300274

Experimental method

X-RAY DIFFRACTION (2.54 Å)