4BTM
TTBK1 in complex with inhibitor
Summary for 4BTM
Entry DOI | 10.2210/pdb4btm/pdb |
Related | 4BTJ 4BTK |
Descriptor | TAU-TUBULIN KINASE 1, SULFATE ION, methyl 2-bromo-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)benzoate, ... (6 entities in total) |
Functional Keywords | transferase, ligand complex, structure-kinetics relationship |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cytoplasm : Q5TCY1 |
Total number of polymer chains | 2 |
Total formula weight | 78741.90 |
Authors | Xue, Y.,Wan, P.,Hillertz, P.,Schweikart, F.,Zhao, Y.,Wissler, L.,Dekker, N. (deposition date: 2013-06-18, release date: 2013-09-25, Last modification date: 2023-12-20) |
Primary citation | Xue, Y.,Wan, P.T.,Hillertz, P.,Schweikart, F.,Zhao, Y.,Wissler, L.,Dekker, N. X-Ray Structural Analysis of Tau-Tubulin Kinase 1 and its Interactions with Small Molecular Inhibitors. Chemmedchem, 8:1846-, 2013 Cited by PubMed: 24039150DOI: 10.1002/CMDC.201300274 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.54 Å) |
Structure validation
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