4BTM
TTBK1 in complex with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | TAU-TUBULIN KINASE 1 | polymer | 337 | 38746.5 | 2 | UniProt (Q5TCY1) Pfam (PF00069) | HOMO SAPIENS (HUMAN) | BRAIN-DERIVED TAU KINASE |
| 2 | C, D, E, G (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | F, J (A, B) | methyl 2-bromo-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)benzoate | non-polymer | 347.2 | 2 | Chemie (F8E) | |||
| 4 | H (B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 5 | I (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | K, L (A, B) | water | water | 18.0 | 359 | Chemie (HOH) |
Sequence modifications
A, B: 25 - 337 (UniProt: Q5TCY1)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | expression tag |
| His 2 | - | expression tag |
| His 3 | - | expression tag |
| His 4 | - | expression tag |
| His 5 | - | expression tag |
| His 6 | - | expression tag |
| His 7 | - | expression tag |
| Ser 8 | - | expression tag |
| Ser 9 | - | expression tag |
| Gly 10 | - | expression tag |
| Val 11 | - | expression tag |
| Asp 12 | - | expression tag |
| Leu 13 | - | expression tag |
| Gly 14 | - | expression tag |
| Thr 15 | - | expression tag |
| Glu 16 | - | expression tag |
| Asn 17 | - | expression tag |
| Leu 18 | - | expression tag |
| Tyr 19 | - | expression tag |
| Phe 20 | - | expression tag |
| Gln 21 | - | expression tag |
| Ser 22 | - | expression tag |
| Asn 23 | - | expression tag |
| Ala 24 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 77493.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1248.8 | |
| All* | Total formula weight | 78741.9 |
